Results 51 to 60 of about 7,619,474 (155)

Human herpesvirus 6A and 6B and NK cells [PDF]

, 2018
Human herpesvirus 6 (HHV-6) comprises two viral species, HHV-6A and HHV-6B, closely related but differing for pathogenic and biological characteristics.
Roberta Rizzo, Di Luca, Dario, Dario Di Luca, Rizzo, Roberta   +3 more
core   +1 more source

Human Herpesviruses-encoded dUTPases: A Family of Proteins that Modulate Dendritic Cell Function and Innate Immunity

Frontiers in Microbiology, 2014
We have previously shown that Epstein-Barr virus (EBV)-encoded dUTPase can modulate innate immune responses through the activation of TLR2 and NF-kappaB signaling. However, whether this novel immune function of the dUTPase is specific for EBV or a common
Maria Eugenia eAriza, Ronald eGlaser, Marshall Vance Williams   +2 more
doaj   +1 more source

Clinical and etiological aspects of human Betaherpesvirus infection 6: a review

Журнал инфектологии, 2022
The literature review is devoted to the modern concept of human betaherpesvirus 6 (human herpesvirus 6; HHV-6). The analysis of the literature mainly for the last five years was carried out.
N. S. Tian, O. V. Goleva, I. V. Babachenko   +2 more
doaj   +1 more source

Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow

VIEW, EarlyView.
Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow. Abstract Metagenomic next‐generation sequencing (mNGS) enables unbiased identification of pathogens directly from clinical specimens. Despite its growing application in
Wen Shu, Qiaomei Guo, Han Yang, Huiqin Jiang, Chunyan He, Xueqing Wang, Yuting Fang, Yue Yin, Liwen Zhong, Zhijing Zhao, Jiatao Lou, Lin Wang   +11 more
wiley   +1 more source

Animal models of human herpesvirus 6 infection

Frontiers in Microbiology, 2013
Human herpesvirus (HHV)-6A and HHV-6B are two enveloped DNA viruses of β-herpesvirus family, infecting over 90% of the population and associated with several diseases, including exanthema subitum (for HHV-6B), multiple sclerosis and encephalitis ...
Joséphine eReynaud, Branka eHorvat
doaj   +1 more source

Shotgun Metagenomic Analysis Reveals Taxonomic and Functional Transitions in the Salivary Microbiome During Periodontal Disease Progression

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To characterise multi‐kingdom salivary microbiome profiles across clinically defined periodontal states and identify stage‐specific taxonomic and functional alterations using shotgun metagenomic sequencing. Materials and Methods In this cross‐sectional study, 204 adults (mean age 40.3 ± 7.6 years) from the SECRETO study (NCT01934725 ...
Muhammed Manzoor, Jaakko Leskelä, Eija Könönen, Leo Lahti, Jukka Putaala, Pirkko J. Pussinen, Susanna Paju   +6 more
wiley   +1 more source

Epidemiology and fitness effects of wood mouse herpesvirus in a natural host population [PDF]

, 2012
Rodent gammaherpesviruses have become important models for understanding human herpesvirus diseases. In particular, interactions between murid herpesvirus 4 and Mus musculus (a non-natural host species) have been extensively studied under controlled ...
Pedersen, Amy B., Knowles, Sarah L.K., Fenton, Andy   +2 more
core   +1 more source

SARS-CoV-2 Infection Associated with HHV-6A Reactivation and an Inhibitory KIR2DL2/HLA-C1 Immunogenetic Profile

Microorganisms
Natural killer (NK) cells are central to antiviral immunity through a balance of activating and inhibitory receptors, including killer immunoglobulin-like receptors (KIRs).
Sabrina Rizzo, Matteo Ferraresi, Giovanni Strazzabosco, Marcello Baroni, Juana Maria Sanz, Angelina Passaro, Daria Bortolotti, Roberta Rizzo, Giovanna Schiuma   +8 more
doaj   +1 more source

Modulatory effects on dendritic cells by human herpesvirus 6

Frontiers in Microbiology, 2015
Human herpesvirus 6A and 6B are β-herpesviruses approaching 100% seroprevalance worldwide. These viruses are involved in several clinical syndromes and have important immunomodulatory effects.
Rasmus eGustafsson, Mattias eSvensson, Anna eFogdell-Hahn   +2 more
doaj   +1 more source

Radiotherapy Enhances the Oncolytic Efficacy of the Novel Oncolytic Herpesvirus VG161 and Amplifies Its Antitumor Immunity in Breast Cancer

Advanced Science, Volume 13, Issue 52, 18 September 2026.
RT promotes VG161 replication in BC and its immunostimulatory transgenes expression, which is mediated by the upregulation of GADD34 and HVEM caused by RT. The combination therapy with VG161 and RT increases the abundances of tumor‐infiltrating lymphocytes and elicits potent systemic antitumor immunity, thereby effectively inhibiting local tumors and ...
Lijuan Lyu, Ming Yi, Ji Chen, Zeda Zhao, Ruocen Liao, Yingnan Wang, Shengtao Hu, Jun Ding, Ronghua Zhao, William Jia, Yinan Shen, Yongchang Wei, Kongming Wu, Zhijun Dai   +13 more
wiley   +1 more source