Results 101 to 110 of about 5,646 (167)

Heterologous Expression of Immature Forms of Human Islet Amyloid Polypeptide in Yeast Triggers Intracellular Aggregation and Cytotoxicity. [PDF]

Front Microbiol, 2020
Raimundo AF, Ferreira S, Farrim MI, Santos CN, Menezes R.   +4 more
europepmc   +1 more source

Human islet amyloid polypeptide-induced β-cell cytotoxicity is linked to formation of α-sheet structure. [PDF]

Protein Sci
Hsu CC, Templin AT, Prosswimmer T, Shea D, Li J, Brooks-Worrell B, Kahn SE, Daggett V.   +7 more
europepmc   +1 more source

Pristine and Hydroxylated Fullerenes Prevent the Aggregation of Human Islet Amyloid Polypeptide and Display Different Inhibitory Mechanisms. [PDF]

Front Chem, 2020
Bai C, Lao Z, Chen Y, Tang Y, Wei G.
europepmc   +1 more source

Human islet amyloid polypeptide oligomers stabilized and probed by MAS NMR

Magnetic Resonance Letters
Ziwei Chang, Zhengfeng Zhang
doaj   +1 more source

The islet tissue plasminogen activator/plasmin system is upregulated with human islet amyloid polypeptide aggregation and protects beta cells from aggregation-induced toxicity. [PDF]

Diabetologia
Esser N, Hogan MF, Templin AT, Akter R, Fountaine BS, Castillo JJ, El-Osta A, El-Osta A, Manathunga L, Zhyvoloup A, Raleigh DP, Zraika S, Hull RL, Kahn SE.   +13 more
europepmc   +1 more source

Non-fibril form but not fibril form of human islet amyloid polypeptide 8-20 changes brain functions in mice. [PDF]

PLoS One
Suginoma H, Owada R, Katano-Toki A, Mori A, Fujioka J, Nakamura K.   +5 more
europepmc   +1 more source

Lipid Modulation in the Formation of β-Sheet Structures. Implications for De Novo Design of Human Islet Amyloid Polypeptide and the Impact on β-Cell Homeostasis. [PDF]

Biomolecules, 2020
Martínez-Navarro I, Díaz-Molina R, Pulido-Capiz A, Mas-Oliva J, Luna-Reyes I, Rodríguez-Velázquez E, Rivero IA, Ramos-Ibarra MA, Alatorre-Meda M, García-González V.   +9 more
europepmc   +1 more source

The Inhibition Effect of Epigallocatechin-3-Gallate on the Co-Aggregation of Amyloid-β and Human Islet Amyloid Polypeptide Revealed by Replica Exchange Molecular Dynamics Simulations. [PDF]

Int J Mol Sci
Li X, Zhang Y, Yang Z, Zhang S, Zhang L.
europepmc   +1 more source

His18 promotes reactive oxidative stress production in copper-ion mediated human islet amyloid polypeptide aggregation. [PDF]

RSC Adv, 2020
Huo G, Chen W, Wang J, Chu X, Xu W, Li B, Zhang Y, Xu B, Zhou X.   +8 more
europepmc   +1 more source

Nucleation of β-rich oligomers and β-barrels in the early aggregation of human islet amyloid polypeptide. [PDF]

Biochim Biophys Acta Mol Basis Dis, 2019
Sun Y, Kakinen A, Xing Y, Pilkington EH, Davis TP, Ke PC, Ding F.   +6 more
europepmc   +1 more source