Results 111 to 120 of about 5,646 (167)

Graphene quantum dots rescue protein dysregulation of pancreatic β-cells exposed to human islet amyloid polypeptide. [PDF]

Nano Res, 2019
Faridi A, Sun Y, Mortimer M, Aranha RR, Nandakumar A, Li Y, Javed I, Kakinen A, Fan Q, Purcell AW, Davis TP, Ding F, Faridi P, Ke PC.   +13 more
europepmc   +1 more source

Profiling the Serum Protein Corona of Fibrillar Human Islet Amyloid Polypeptide. [PDF]

ACS Nano, 2018
Pilkington EH, Gustafsson OJR, Xing Y, Hernandez-Fernaud J, Zampronio C, Kakinen A, Faridi A, Ding F, Wilson P, Ke PC, Davis TP.   +10 more
europepmc   +1 more source

Loss of perlecan heparan sulfate glycosaminoglycans lowers body weight and decreases islet amyloid deposition in human islet amyloid polypeptide transgenic mice. [PDF]

Protein Eng Des Sel, 2019
Templin AT, Mellati M, Soininen R, Hogan MF, Esser N, Castillo JJ, Zraika S, Kahn SE, Hull RL.   +8 more
europepmc   +1 more source

Cholesterol-sensing role of phenylalanine in the interaction of human islet amyloid polypeptide with lipid bilayers. [PDF]

RSC Adv, 2018
Hao R, Li Y, Guan L, Lu T, Meng F, Wang C, Li F.   +6 more
europepmc   +1 more source

Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc. [PDF]

Exp Mol Med, 2019
Wu X, Liao Z, Wang K, Hua W, Liu X, Song Y, Zhang Y, Yang S, Yang C.   +8 more
europepmc   +1 more source

Dual effect of PEG-PE micelle over the oligomerization and fibrillation of human islet amyloid polypeptide. [PDF]

Sci Rep, 2018
Fang X, Yousaf M, Huang Q, Yang Y, Wang C.   +4 more
europepmc   +1 more source

Influence of Aluminium and EGCG on Fibrillation and Aggregation of Human Islet Amyloid Polypeptide. [PDF]

J Diabetes Res, 2016
Xu ZX, Zhang Q, Ma GL, Chen CH, He YM, Xu LH, Zhang Y, Zhou GR, Li ZH, Yang HJ, Zhou P.   +10 more
europepmc   +1 more source

Islet amyloid polypeptide immunoreactivity in the human fetal pancreas [PDF]

Diabetologia, 1992
Islet amyloid polypeptide is known to localize to the adult human Beta cell. We analysed the immunoreactivity for islet amyloid polypeptide in a series of 29 human fetal pancreata (9-24 weeks of gestation) with respect to age dependency and cellular localization using an antibody raised against synthetic rat islet amyloid polypeptide 12-37.
Ole Madsen, Madsen O D, Klöppel G
exaly   +4 more sources

Fibril Structure of Human Islet Amyloid Polypeptide [PDF]

Journal of Biological Chemistry, 2012
Misfolding and amyloid fibril formation by human islet amyloid polypeptide (hIAPP) are thought to be important in the pathogenesis of type 2 diabetes, but the structures of the misfolded forms remain poorly understood. Here we developed an approach that combines site-directed spin labeling with continuous wave and pulsed EPR to investigate local ...
Ian Haworth, Balachandra G Hegde, Ralf Langen   +2 more
exaly   +3 more sources