Results 111 to 120 of about 119,573 (312)

Characterisation of keratinocyte-derived epidermal signals in the initiation of contact hypersensitivity to chemicals

, 2015
Contact hypersensitivity reactions result from an adaptive immune response following topical exposure to chemical allergen. The initiation of this response requires the production of an inflammatory micro-environment, however the contribution of ...
Summerfield, VL
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Wound stimulation by growth-arrested human keratinocytes and fibroblasts: HP802-247, a new-generation allogeneic tissue engineering product [PDF]

, 2010
HP802-247 is a new-generation, allogeneic tissue engineering product consisting of growth-arrested, human keratinocytes (K) and fibroblasts (F) delivered in a fibrin matrix by a spray ...
Hunziker, Thomas, Daroczy, Judit, Goedkoop, René, You, Percy Hou Kang, Rolland, Eric, de Roos, Kees-Peter, Juliet, Rodney, Lijnen, Raf   +7 more
core   +1 more source

Multi‐Axis Stretchable Zippers for Personalized Wound Healing

Advanced Science, EarlyView.
Multi‐axis stretchable zippers can adapt to complex wound morphologies and enable personalized wound treatment through programmable contraction. This morphological matching strategy helps accelerate wound closure, improve blood perfusion, promote epithelial regeneration, and enhance collagen remodeling, pioneering new directions for personalized and ...
Siyuan Cai, Guang Yao, Zijian Chen, Shiqi Zhou, Peisi Li, Liheng Lin, Huake Yang, Ziyi Zhou, Linbo Jin, Xingyi Gan, Chenzheng Zhou, Zhen Cai, Taisong Pan, Min Gao, Dongli Fan, Yuan Lin, Yiming Zhang   +16 more
wiley   +1 more source

Wavelength‐Dependent Photobiomodulation Regulates Macrophage Polarization via Mitochondrial Dynamics and Metabolic Reprogramming

Advanced Science, EarlyView.
Light wavelength encodes distinct macrophage fates through mitochondrial and metabolic remodeling. Red 625 nm irradiation induces glycolysis, mitochondrial fission, and M1 polarization, whereas near‐infrared 850 nm irradiation promotes fatty acid oxidation, mitochondrial fusion, and M2 polarization.
Qiusheng Shi, Hao Jia, Jianfei Dong, Linhao Li, Jingqi Cao, Xun Chen, Zhenzhen Jia, Jing Na, Zhijie Yang, Xinyuan Chen, Yubo Fan, Shuhua Yue, Lisha Zheng   +12 more
wiley   +1 more source

The time-dependent expression of keratins 5 and 13 during the reepithelialization of human skin wounds [PDF]

, 1993
The time-dependent reepithelialization of 55 human surgical skin wounds with a wound age between 8h and more than 2 months was investigated by the immunohistochemical localization of cytokeratins 5 and 13.
Penning, R., Eisenmenger, Wolfgang, Nerlich, A., Tübel, J., Betz, P.   +4 more
core   +1 more source

Hair Follicle Seedling Cryomicroneedles from Hierarchical Microfluidic Organoid on a Chip

Advanced Science, EarlyView.
In this paper, a hierarchical microfluidic chip is developed to produce uniform hair follicle organoids (HFOs) in cryomicroneedles. Cryopreservation agents encapsulate HFOs, preserving viability and hair growth potential. The cryomicroneedles enable simple intradermal transplantation with good skin penetration.
Xinyue Cao, Dongyu Xu, Minhui Lu, Yuanjin Zhao   +3 more
wiley   +1 more source

Orf virus (ORFV) infection in a three-dimensional human skin model: Characteristic cellular alterations and interference with keratinocyte differentiation.

PLoS ONE, 2019
ORF virus (ORFV) is the causative agent of contagious ecthyma, a pustular dermatitis of small ruminants and humans. Even though the development of lesions caused by ORFV was extensively studied in animals, only limited knowledge exists about the lesion ...
Mahmod Muhsen, Martina Protschka, Laura E Schneider, Uwe Müller, Gabriele Köhler, Thomas M Magin, Mathias Büttner, Gottfried Alber, Sabine Siegemund   +8 more
doaj   +1 more source

Effect of leptin on human epidermal keratinocytes.

, 2015
(A) Ob-R mRNA expression in human epidermal keratinocytes. (B) Ob-R protein expression in human epidermal keratinocytes. (C) Effect of leptin on the proliferation of human epidermal keratinocytes.
Susumu Tadokoro (599626), Reiko Tokuyama (599623), Hirochika Umeki (599622), Kazuhito Satomura (599629), Shinji Ide (599624), Shiki Kataoka (709691), Seiko Tatehara (599628)   +6 more
core   +1 more source

Epidermal METTL1‐Mediated m7G Modification Drives Psoriatic Inflammation by Stabilizing Bdkrb1 and Orchestrating Neutrophil Recruitment

Advanced Science, EarlyView.
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang, Jiayi Lu, Sihao Yan, Yirui Wang, Zhuo Li, Weiwei Chen, Yang Han, Ziyan Zhang, Yafen Yu, Qi Zhen, Liangdan Sun   +10 more
wiley   +1 more source

An in vitro investigation into the pigmentary phenotype of melanocytes and keratinocyte co-cultures to improve wound healing

, 2013
Includes abstract.Includes bibliographical references.On healing, partial-thickness burn wounds usually result in depigmentation of the skin. This is due to the loss of melanocytes.
Chang, Ju-Wei
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