Results 121 to 130 of about 119,573 (312)

Photosensitization of the sunscreen octyl-p-dimethylaminobenzoate by UVA in human melanocytes but not in keratinocytes

, 2001
Sunscreens penetrate human epidermis and modify the biology of proliferating cells. This study addressed the question whether the UV response of cultured human cells is affected by direct treatment with nontoxic levels of sunscreens.
Green, Adele, Xu, Chunxia, Parsons, Peter G., Parisi, Alfio   +3 more
core   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

Advanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong, Zijian Huang, Xuanwu Wang, Zhenghui Feng, Wei Liu, Bingding Huang   +5 more
wiley   +1 more source

In Situ Thai Apis mellifera Propolis Film as Potential Protective Phytopharmaceuticals Against UVB-Induced HaCaT Keratinocyte Damage

Pharmaceuticals
Background/Objectives: Propolis is well recognized for its antioxidant, anti-inflammatory, and wound-healing properties, supporting its cutaneous application in phytopharmaceuticals for the management of ultraviolet B (UVB)-induced skin damage.
Takron Chantadee, Anyamanee Chatsirisupachai, Ampai Phrutivorapongkul, Sunee Chansakaow, Sasithorn Sirilun, Onusa Thamsermsang   +5 more
doaj   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source

Cytoneme-mediated intercellular signaling in keratinocytes is essential for epidermal remodeling in zebrafish

eLife
The skin, the largest organ, functions as a primary defense mechanism. Epidermal stem cells supply undifferentiated keratinocytes that differentiate as they migrate toward the outermost skin layer.
Yi Wang, Thomas Nguyen, Qingan He, Oliver Has, Kiarash Forouzesh, Dae Seok Eom   +5 more
doaj   +1 more source

i‐Tac: Inverse Design of 3D‐Printed Tactile Elastomers with Tuneable Optical and Mechanical Properties

Advanced Intelligent Systems, EarlyView.
Inspired by the multi‐tissue architecture of the human fingertip dermis (A), this work introduces a mixture design using three PolyJet materials (AC/TM/GM) to expand the achievable elastomer property space (B). An inverse design pipeline (i‐Tac) is developed to map target optical/mechanical requirements to optimal material compositions (C), enabling ...
Wen Fan, Dandan Zhang
wiley   +1 more source

Pseudomonas aeruginosa flagellum is critical for invasion, cutaneous persistence and induction of inflammatory response of skin epidermis

Virulence, 2018
Pseudomonas aeruginosa, an opportunistic pathogen involved in skin and lung diseases, possesses numerous virulence factors, including type 2 and 3 secretion systems (T2SS and T3SS) and its flagellum, whose functions remain poorly known during cutaneous ...
Magali Garcia, Eric Morello, Julien Garnier, Christine Barrault, Martine Garnier, Christophe Burucoa, Jean-Claude Lecron, Mustapha Si-Tahar, François-Xavier Bernard, Charles Bodet   +9 more
doaj   +1 more source

Targeted Anti‐IL‐1 Immunomodulatory Therapy in Pediatric Onset PPP1R13L‐Related Arrhythmogenic Cardiomyopathy

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive loss‐of‐function variants in PPP1R13L cause an ultra‐rare cardiocutaneous syndrome characterized by rapidly progressive arrhythmogenic cardiomyopathy (ACM). PPP1R13L encodes iASPP, which has two potentially overlapping mechanisms driving ACM as both a regulator of NFκB‐mediated inflammation and a binding partner within the ...
Aaron Renberg, Savannah Coppersmith, Owen Merritt, Amer Heider, Adam Helms, Thomas Michniacki, Jack Luxford, Sarah Josephi‐Taylor, Philip Roberts, Joshua Meisner   +9 more
wiley   +1 more source

Biofilm Exoproteins From Staphylococcus Species Impede Re‐Epithelialization of Nasal Epithelial Cells During Wound Healing and Cease Ciliary Beat Frequency

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Chronic rhinosinusitis (CRS) is an inflammatory disease with many different contributing factors, including bacterial infection. CRS patients are typically managed with medical therapies; however, these treatments frequently fail, leaving surgery as the only viable option.
Sintayehu Ambachew, Mahnaz Ramezanpour, Clare M. Cooksley, Emma F. Barry, Lindsay Durr, Kevin Aaron Fenix, P. J. Wormald, Alkis J. Psaltis, Sarah Vreugde   +8 more
wiley   +1 more source

Revitalising Brewers' Spent Grains and Enriching With Biogenic Compounds Through the Fermentation of Fructophilic Lactic Acid Bacteria and Yeasts

Microbial Biotechnology
The large output of spent grains from the brewing industry presents environmental concerns but also offers promising nutritional and functional potential for valorization by researchers and industrial stakeholders.
Alessandro Stringari, Ali Zein Alabiden Tlais, Stefano Tonini, Daniela Pinto, Giorgia Mondadori, Pasquale Filannino, Raffaella Di Cagno, Marco Gobbetti   +7 more
doaj   +1 more source