Results 21 to 30 of about 74,702 (247)

Tumor-Specific CircRNA-Derived Antigen Peptide Identification for Hepatobiliary Tumors

Engineering, 2023
The application of tumor antigen-based immunotherapy is hindered by the rarity of validated immunogenic peptides. In this study, we aimed to investigate the potential of circular RNAs (circRNAs) as a novel source of tumor antigen peptides in ...
Wenwen Wang, Lili Ma, Zheng Xing, Tinggan Yuan, Jinxia Bao, Yanjing Zhu, Xiaofang Zhao, Yan Zhao, Yali Zong, Yani Zhang, Siyun Shen, Xinyao Qiu, Shuai Yang, Hongyang Wang, Dong Gao, Peng Wang, Lei Chen   +16 more
doaj   +1 more source

HLA‐B27 association of autoimmune encephalitis induced by PD‐L1 inhibitor

Annals of Clinical and Translational Neurology, 2020
Objective While immune checkpoint inhibitors are increasingly used for various cancers, unpredictable immune‐related adverse events (irAEs) such as autoimmune encephalitis is life‐threatening.
Hyeyeon Chang, Yong‐Won Shin, Bhumsuk Keam, Miso Kim, Seock‐Ah Im, Soon‐Tae Lee   +5 more
doaj   +1 more source

A Novel Finding of an HLA Allele’s and a Haplotype’s Relationship with SARS-CoV-2 Vaccine-Associated Subacute Thyroiditis

Vaccines, 2022
Subacute thyroiditis (SAT) is a thyroid disease associated with viral infections. Its relationship with major histocompatibility complex (MHC) antigens was shown before.
Melisa Sahin Tekin, Goknur Yorulmaz, Emel Yantir, Eren Gunduz, Ertugrul Colak   +4 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

FREQUENCY OF HUMAN LEUKOCYTE ANTIGEN B27(HLA-B27) IN CLINICALLY DIAGNOSED ANKYLOSING SPONDYLITIS; A STUDY OF 100 CASES

Pakistan Armed Forces Medical Journal, 2019
Objective: To determine the frequency of Human leukocyte antigen B-27 patients with clinically diagnosed ankylosing spondylitis and frequency of peripheral joints‟ involvement and serum inflammatory markers (raised serum C-reactive protein & erythrocyte
Sardar Muhammad, Amer Fakhr, Muhammad Adnan Manzar, Farzana Hakim, Taimoor Ashraf Khan, Bilal Ahmad   +5 more
doaj   +4 more sources

Human leukocyte antigen-B alleles in spondyloarthritides: A single-center, prospective, cross-sectional study

Indian Journal of Rheumatology, 2022
Objective: The objective of this study is to study distribution of human leukocyte antigen (HLA)-B alleles in Spondyloarthritis (SpA) and to find its clinical relevance in the patient management.
Jeet Hemantkumar Patel, Ved Chaturvedi, Lalit Duggal, Neeraj Jain, Gurbir Bhandari, Monika Jain   +5 more
doaj   +1 more source

HLA Preferences for Conserved Epitopes: A Potential Mechanism for Hepatitis C Clearance

Frontiers in Immunology, 2015
Hepatitis C virus (HCV) infections affect more than 170 million people worldwide. Most of these individuals are chronically infected, but some clear the infection rapidly.
Xiangyu eRao, Ilka eHoof, Debbie eVan Baarle, Debbie eVan Baarle, Can eKeşmir, Johannes eTextor   +5 more
doaj   +1 more source

Comparative Molecular Analysis and Antigenicity Prediction of an Outer Membrane Protein (ompC) of Non-typhoidal Serovars Isolated from Different Food Animals in Lagos, Nigeria

Bioinformatics and Biology Insights, 2023
Non-typhoidal Salmonella (NTS) infections occur globally with high morbidity and mortality. The public health challenge caused is exacerbated by increasing rate of antibiotic resistance and absence of NTS vaccine.
Morufat Yusuf, Abraham Ajayi, Utibeima Udo Essiet, Oyin Oduyebo, Adeyemi Isaac Adeleye, Stella Ifeanyi Smith   +5 more
doaj   +1 more source

The Immunological Epigenetic Landscape of the Human Life Trajectory

Biomedicines, 2022
Adaptive immunity changes over an individual’s lifetime, maturing by adulthood and diminishing with old age. Epigenetic mechanisms involving DNA and histone methylation form the molecular basis of immunological memory during lymphocyte development ...
Iva Juříčková, Michael Hudec, Felix Votava, Jan Vosáhlo, Saak Victor Ovsepian, Marie Černá, Valerie Bríd O’Leary   +6 more
doaj   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source