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Modifiable and Non-Modifiable Factors That Affect Human Milk Oligosaccharides Composition. [PDF]
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Oligosaccharides of Human Milk
Nature, 1957THE presence of fucose as a constituent sugar in oligosaccharides obtained from human milk was reported by Kuhn1 in 1952. Since that time Kuhn and his associates have characterized four oligosaccharides from this source, in all of which fucose is found: a trisaccharide, fucosido-lactose; two pentasaccharides referred to as lacto-N-fucopentaoses I and ...
F H, MALPRESS, F E, HYTTEN
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Biotechnological production of human milk oligosaccharides
Biotechnology Advances, 2012Human milk contains a large variety of oligosaccharides (HMOs) that have the potential to modulate the gut flora, affect different gastrointestinal functions, and influence inflammatory processes. This review introduces the recent advances in the microbial and coupled enzymatic methods to produce HMOs with grouping them into trisaccharides ...
Jaehan Kim, Jin-Ho Seo, Nam Soo Han
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Journal of Pediatric Gastroenterology and Nutrition, 2016
Human milk oligosaccharides are very complex molecules and hence are difficult to synthesize. These specialty carbohydrates are consequently very expensive and not available in sufficient quantities. Enzymatic synthesis is efficient for relatively simple carbohydrates but cannot be used for more complex carbohydrates.
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Human milk oligosaccharides are very complex molecules and hence are difficult to synthesize. These specialty carbohydrates are consequently very expensive and not available in sufficient quantities. Enzymatic synthesis is efficient for relatively simple carbohydrates but cannot be used for more complex carbohydrates.
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2001
Human milk is a unique reservoir of oligosaccharides. The presence of many of these oligosaccharides is determined genetically and is related to the Lewis blood group and secretor antigen status of each donor. A method to quantitate neutral human milk oligosaccharides was developed.
R. Erney +4 more
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Human milk is a unique reservoir of oligosaccharides. The presence of many of these oligosaccharides is determined genetically and is related to the Lewis blood group and secretor antigen status of each donor. A method to quantitate neutral human milk oligosaccharides was developed.
R. Erney +4 more
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Human milk oligosaccharides: Only the breast
Journal of Paediatrics and Child Health, 1997Abstract: Over 100 years ago it was first deduced that a major component of human milk must be an unidentified carbohydrate that was not found in cows milk. At first this was thought to be a form of lactose and was called gynolactose. We now know that this was not a single carbohydrate but a complex mixture of approximately 130 different ...
P, McVeagh, J B, Miller
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Human milk oligosaccharides: prebiotics and beyond
Nutrition Reviews, 2009Human milk oligosaccharides (HMO) are complex glycans that are present at very high concentrations in human milk but not in infant formula. The significant energy expended by mothers to make these complex glycans suggests they must be important. How do maternal HMOs benefit the breast-fed infant? How are HMOs synthesized in the human mammary gland? How
Lars Bode, Bode Lars
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Bifidobacterial utilization of human milk oligosaccharides
International Journal of Food Microbiology, 2011A promising strategy to improve health is the rational manipulation of one's beneficial microbiota via dietary interventions. This is observed in nature where specific bifidobacteria utilize human milk oligosaccharides (HMOs) that are encountered within the breast-fed infant colon. Bifidobacterium longum subsp.
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Human milk and related oligosaccharides as prebiotics
Current Opinion in Biotechnology, 2013Human milk oligosaccharides (HMO) are believed to have a range of biological activities beyond providing nutrition to the infant. Principal among these is that they may act as prebiotics. Prebiotics are dietary ingredients, usually oligosaccharides that provide a health benefit to the host mediated by the modulation of the human gut microbiota.
Daniela, Barile, Robert A, Rastall
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The functional biology of human milk oligosaccharides
Early Human Development, 2015Human milk oligosaccharides (HMOs) are a group of complex sugars that are highly abundant in human milk, but currently not present in infant formula. More than a hundred different HMOs have been identified so far. The amount and composition of HMOs are highly variable between women, and each structurally defined HMO might have a distinct functionality.
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