Results 71 to 80 of about 7,369,915 (195)
Polyomavirus infections and its clinical relevance in cancer patients: A Prospective Study
Summary: BK and JC polyomaviruses (PyV) have been demonstrated to be associated with the pathogenesis of various human cancers. We aimed to investigate the impact of BK and JC polyomavirus infections on several clinical parameters in different human ...
Samah A. Loutfy +6 more
doaj +1 more source
Isolation and characterization of WUPyV in polarized human airway epithelial cells
Background Washington University polyomavirus (WUPyV) is a novel human polyomavirus detected in childwith acute respiratory infection in 2007. However, the relationship between WUPyV and respiratory diseases has yet to be established for lacking of a ...
Chao Wang +7 more
doaj +1 more source
Cross‐Neutralizing and Broadly Neutralizing Human Antibodies Against Nonenveloped Viruses
In this review article, Marchand et al. compare cross ‐ and broadly ‐neutralizing human antibodies against non ‐ enveloped viruses from several major families, discussing their structural characteristics, neutralization mechanisms and relevance for the development of antiviral vaccines and therapeutics.
Sarah Marchand +2 more
wiley +1 more source
The Potential Role of BK and JC Polyomaviruses in Urothelial Cancer
Background: BK and JC polyomaviruses are perceived as the two most common human polyomaviruses (HPyVs). These two viruses inhabit the epithelial surfaces of the bladder and kidney as the primary site of replication and latency.
Kawther A. AlMalaki +2 more
doaj +3 more sources
The human neurotropic virus JC Polyomavirus, a member of the Polyomaviridae family, is the opportunistic infectious agent causing progressive multifocal leukoencephalopathy, typically in immunocompromised individuals.
Vijay Harypursat +3 more
doaj +1 more source
ABSTRACT Human respiratory syncytial virus (HRSV) is the leading cause of acute lower respiratory tract infections in infants and represents a major burden to public health systems worldwide. Despite its epidemiological relevance, genomic surveillance of HRSV in Brazil remains limited.
Alessandra Pavan Lamarca +10 more
wiley +1 more source
Merkel Cell Polyomavirus and Two Previously Unknown Polyomaviruses Are Chronically Shed from Human Skin [PDF]
SummaryMounting evidence indicates that Merkel cell polyomavirus (MCV), a circular double-stranded DNA virus, is a causal factor underlying a highly lethal form of skin cancer known as Merkel cell carcinoma.
Rachel M. Schowalter +9 more
core +1 more source
IntroductionHuman polyomaviruses (HPyVs) cause persistent/latent infections in a large fraction of the population. HPyV infections may cause severe diseases in immunocompromised patients.
Jérôme T. J. Nicol +16 more
doaj +1 more source
ABSTRACT Background Calcineurin inhibitor (CNI) nephrotoxicity drives long‐term kidney‐function decline after simultaneous pancreas‐kidney (SPK) and liver‐kidney (LK) transplantation, but belatacept conversion, as an alternative strategy, is poorly studied in these recipients, whose non‐kidney allograft rejection risk differs.
Dusan Harmacek +7 more
wiley +1 more source
Entering the Age of Specificity in T Cell Immunity
ABSTRACT The discovery of MHC restriction, the resolution of peptide–MHC structure, and the identification of the T cell receptor gene quickly centered epitope‐level specificity as a core concern of T cell biology. Epitope mapping culminated in functional peptide‐based stimulation assays and tetramer staining, which together provide exquisite ...
Paul G. Thomas
wiley +1 more source

