Results 81 to 90 of about 7,369,915 (195)
Seroprevalence of human polyomavirus 9 and cross-reactivity to African green monkey-derived lymphotropic polyomavirus [PDF]
Human polyomavirus 9 (HPyV9) was discovered recently in immunocompromised patients and shown to be genetically closely related to B-lymphotropic polyomavirus (LPyV). No serological data are available for HPyV9, but human antibodies against LPyV have been
Klein, Marcus +5 more
core +1 more source
ABSTRACT Background In Cameroon, national influenza surveillance identifies influenza‐positive cases, but the causes of non‐influenza ARIs remain poorly characterized. We applied metagenomic next‐generation sequencing (mNGS) to investigate respiratory pathogens in influenza‐negative nasopharyngeal swabs collected through national influenza surveillance.
Modiyinji Abdou Fatawou +9 more
wiley +1 more source
Polyomavirus – an emergent pathogen in transplant recipients [PDF]
Medical centers that work with transplants often face opportunisticinfections that demand specific tools to make diagnosis. Theprevalence of latent polyomavirus infections is high, and the mostcommon site of latency of the most prevalent polyomavirus in ...
Bárbara Tengaten Fontanelle +8 more
core
The Significance of cGAS‐STING Signaling in Response to Oncogenic Viruses
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Limei Guo +4 more
wiley +1 more source
Polyomaviruses (PyVs) are known to infect a wide range of vertebrates and invertebrates and are associated with a broad spectrum of diseases, including cancers, particularly in immune-suppressed hosts. A novel polyomavirus, designated rat polyomavirus 2 (
Lora H. Rigatti +4 more
doaj +1 more source
While several oncogenic pathogens cause site‐specific cancers, uncertainties remain about many other chronic infections and combined pathogen effects, especially in non‐Western populations. Using a large case–cohort study nested within the China Kadoorie Biobank, the authors found that co‐infection was common, with a mean of 10 pathogens per individual.
Ling Yang +212 more
wiley +1 more source
Polyomavirus Large T Can Support DNA Replication in Human Cells [PDF]
Human cells are generally thought to be nonpermissive for polyomavirus (Py) DNA replication. Using transient transfection, we show that Py large T-antigen (LT) was able to support replication of a Py origin-containing plasmid in two human cell lines ...
Androphy, Elliot J. +2 more
core +1 more source
Next‐Generation Sequencing Methods for Sensitive Hepatitis B Viral Genome Analysis: A European Study
ABSTRACT This multicentre study investigated the utility of next‐generation sequencing (NGS) to detect and generate hepatitis B virus (HBV) genomes in samples of low viral load (from 0.2 to 6207 IU/mL). 23 HBV DNA‐positive plasma samples of genotypes A‐E and one HBV‐negative control sample were assayed blindly via 9 established NGS methods from 6 ...
Michael X. Fu +28 more
wiley +1 more source
Brincidofovir inhibits polyomavirus infection in vivo
Polyomaviruses are species-specific DNA viruses that can cause disease in immunocompromised individuals. Despite their role as the causative agents for several diseases, there are no currently approved antivirals for treating polyomavirus infection ...
Arrienne B. Butic +6 more
doaj +1 more source
A novel polyomavirus from the nasal cavity of a giant panda (Ailuropoda melanoleuca)
Background Polyomaviruses infect a wide variety of mammalian and avian hosts with a broad spectrum of outcomes including asymptomatic infection, acute systemic disease, and tumor induction.
Dunwu Qi +12 more
doaj +1 more source

