Background Merkel Cell Carcinoma (MCC) is an aggressive skin cancer that is three times deadlier than melanoma. In 2008, it was found that 80% of MCC cases are caused by the genomic integration of a novel polyomavirus, Merkel Cell Polyomavirus (MCPyV ...
Kaira R. Thevenin +4 more
doaj +1 more source
Merkel cell polyomavirus detected in head and neck carcinomas from Chile
Background The role of human polyomaviruses (HPyVs) in epithelial tumors such as head and neck carcinomas (HNSCCs) including oral and oropharyngeal carcinomas has not been established. In this study, we evaluated for the first time the presence of Merkel
Juan P. Muñoz +11 more
doaj +1 more source
Propagation of the Human Polyomavirus, JCV, in Human Neuroblastoma Cell Lines
Susceptibility to infection by the human polyomavirus, JCV, is determined by intracellular mechanisms which control transcription and replication. Originally thought to propagate well only in human cells of oligodendroglial lineage, JCV has recently been shown to infect astrocytes, astrogliomas, and a neuroblastoma cell line.
Shinohara, Toshiya +2 more
openaire +2 more sources
The Polyomaviridae constitute a family of small DNA viruses infecting a variety of hosts. In humans, polyomaviruses can cause infections of the central nervous system, urinary tract, skin, and possibly the respiratory tract.
Els van der Meijden +5 more
doaj +1 more source
Human polyomavirus BKPyV and JCPyV serostatus has no impact on women´s human papillomavirus infection outcome. [PDF]
Laine HK +5 more
europepmc +1 more source
Natural History of Incident and Persistent Cutaneous Human Papillomavirus and Human Polyomavirus Infections. [PDF]
Amorrortu RP +12 more
europepmc +1 more source
Translating genomic exploration of the family Polyomaviridae into confident human polyomavirus detection. [PDF]
Kamminga S +7 more
europepmc +1 more source
Kimura disease forming a human polyomavirus 6-negative parotid gland nodule with prominent squamous metaplasia in a young female: A case report. [PDF]
Yorita K +9 more
europepmc +1 more source
Natural History of Cutaneous Human Polyomavirus Infection in Healthy Individuals. [PDF]
Bopp L +5 more
europepmc +1 more source
Polyomavirus large T antigens: Unraveling a complex interactome
All members of the polyomavirus family encode a large T antigen (LT) protein that plays essential roles in viral DNA replication, regulation of viral gene expression, and the manipulation of numerous cellular pathways.
Matthew R. Googins +3 more
doaj +1 more source

