Results 121 to 130 of about 19,301 (228)

N-alpha-acetylation of Huntingtin protein increases its propensity to aggregate. [PDF]

J Biol Chem, 2021
Gottlieb L, Guo L, Shorter J, Marmorstein R.   +3 more
europepmc   +1 more source

Mutant Huntingtin Protein Interaction Map Implicates Dysregulation of Multiple Cellular Pathways in Neurodegeneration of Huntington's Disease. [PDF]

J Huntingtons Dis, 2022
Podvin S, Rosenthal SB, Poon W, Wei E, Fisch KM, Hook V.   +5 more
europepmc   +1 more source

Huntingtin-Interacting Protein 1 Influences Worm and Mouse Presynaptic Function and ProtectsCaenorhabditis elegansNeurons against Mutant Polyglutamine Toxicity [PDF]

, 2007
J. Alex Parker, Martina Metzler, John Georgiou, Marilyne Mage, John Roder, Ann M. Rose, Michael R. Hayden, Christian Néri   +7 more
openalex   +1 more source

Huntingtin Protein Measurement [PDF]

, 2020
openaire   +1 more source

Lowering mutant huntingtin protein [PDF]

Nature Reviews Drug Discovery, 2019
openaire   +1 more source

Fighting the Huntington's Disease with a G-Quadruplex-Forming Aptamer Specifically Binding to Mutant Huntingtin Protein: Biophysical Characterization, In Vitro and In Vivo Studies. [PDF]

Int J Mol Sci, 2022
Riccardi C, D'Aria F, Digilio FA, Carillo MR, Amato J, Fasano D, De Rosa L, Paladino S, Melone MAB, Montesarchio D, Giancola C.   +10 more
europepmc   +1 more source

Huntingtin-Interacting Protein 1 [PDF]

, 2020
openaire   +1 more source

Differential effects of overexpression of mutant huntingtin and TDP-43 in agouti-related protein neurons in the arcuate nucleus of the hypothalamus in mice

Oraha, Jennifer, Wagner, Ronja, Bergh, Sofia, Lee, Nicola J, Kirik, Deniz, Petersén, Åsa   +5 more
openalex   +2 more sources

A C-terminal ataxin-2 disordered region promotes Huntingtin protein aggregation and neurodegeneration in Drosophila models of Huntington's disease. [PDF]

G3 (Bethesda), 2021
Huelsmeier J, Walker E, Bakthavachalu B, Ramaswami M.   +3 more
europepmc   +1 more source

Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila [PDF]

, 2003
Shermali Gunawardena, Lu‐Shiun Her, Richard G. Brusch, Robert A. Laymon, Ingrid R. Niesman, Beth Gordesky-Gold, Louis Sintasath, Nancy M. Bonini, Lawrence S.B. Goldstein   +8 more
openalex   +1 more source