Results 131 to 140 of about 19,301 (228)

Allele-Specific Knockdown of Mutant Huntingtin Protein via Editing at Coding Region Single Nucleotide Polymorphism Heterozygosities. [PDF]

Hum Gene Ther, 2022
Oikemus SR, Pfister EL, Sapp E, Chase KO, Kennington LA, Hudgens E, Miller R, Zhu LJ, Chaudhary A, Mick EO, Sena-Esteves M, Wolfe SA, DiFiglia M, Aronin N, Brodsky MH.   +14 more
europepmc   +1 more source

Huntingtin-associated protein 1 regulates postnatal neurogenesis and neurotrophin receptor sorting [PDF]

, 2013
Jianxing Xiang, Hao Yang, Ting Zhao, Miao Sun, Xingshun Xu, Xin‐Fu Zhou, Shihua Li, Xiao‐Jiang Li   +7 more
openalex   +1 more source

Polyglutamine-Rich Suppressors of Huntingtin Toxicity Act Upstream of Hsp70 and Sti1 in Spatial Quality Control of Amyloid-Like Proteins

, 2014
Katie J. Wolfe, Hong Yu Ren, Philipp Trepte, Douglas Cyr   +3 more
openalex   +2 more sources

Ultrasensitive measurement of huntingtin protein in cerebrospinal fluid demonstrates increase with Huntington disease stage and decrease following brain huntingtin suppression [PDF]

, 2015
Amber L. Southwell, Stephen Smith, Tessa R. Davis, Nicholas S. Caron, Erika B. Villanueva, Yuanyun Xie, Jennifer A. Collins, Min Li Ye, Aaron Sturrock, Blair R. Leavitt, Adam G. Schrum, Michael R. Hayden   +11 more
openalex   +1 more source

BDNF and Huntingtin protein modifications by manganese: implications for striatal medium spiny neuron pathology in manganese neurotoxicity [PDF]

, 2014
Kirstie H. Stansfield, Terry Jo Bichell, Aaron B. Bowman, Tomás R. Guilarte   +3 more
openalex   +1 more source

Analysis of oxidative events induced by expanded polyglutamine huntingtin exon 1 that are differentially restored by expression of heat shock proteins or treatment with an antioxidant [PDF]

, 2006
Wance Firdaus, Andreas Wyttenbach, Chantal Diaz‐Latoud, R. William Currie, André‐Patrick Arrigo   +4 more
openalex   +1 more source

Caspase-6 Activity in a BACHD Mouse Modulates Steady-State Levels of Mutant Huntingtin Protein But Is Not Necessary for Production of a 586 Amino Acid Proteolytic Fragment [PDF]

, 2012
Juliette Gafni, Theodora Papanikolaou, Francesco DeGiacomo, Jennifer Holcomb, Sylvia Chen, Liliana Menalled, Andrea E. Kudwa, J. Fitzpatrick, Sam Miller, Sylvie Ramboz, Pasi Tuunanen, Kimmo Lehtimäki, X. William Yang, Larry Park, Seung Kwak, David Howland, Hyunsun Park, Lisa Ellerby   +17 more
openalex   +1 more source

Modulation of huntingtin degradation by cAMP-dependent protein kinase A (PKA) phosphorylation of C-HEAT domain Ser2550 [PDF]

, 2022
Yejin Lee, Hyeongju Kim, Douglas Barker, Ravi Vijayvargia, Ranjit Singh Atwal, Harrison Specht, Hasmik Keshishian, Steven A. Carr, Ramee Lee, Seung Kwak, Kyung-gi Hyun, Jacob M. Loupe, Marcy E. MacDonald, Ji‐Joon Song, Ihn Sik Seong   +14 more
openalex   +1 more source

Early whole-body mutant huntingtin lowering averts changes in proteins and lipids important for synapse function and white matter maintenance in the LacQ140 mouse model [PDF]

, 2023
Kai Shing, Ellen Sapp, Adel Boudi, Sophia Liu, Connor Seeley, Deanna M. Marchionini, Marian DiFiglia, Kimberly B. Kegel-Gleason   +7 more
openalex   +1 more source

Expression and Localization of Huntingtin-Associated Protein 1 (HAP1) in the Human Digestive System

, 2018
Li Tian, Shihua Li, Xiaozhong Gao, Qiang Cai, Xiaojiang Li   +4 more
openalex   +2 more sources