Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent (ATPS) systems: Its scale-up and prospects for the future production of high-value biologics [PDF]
, 2007 The future challenges in bioprocessing include developing new downstream processes for the purification and manufacture of the protein based medicines of the future to relieve the predicted bottleneck being produced by increasingly high titres from ...
Sutherland, I A
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Natural AChE inhibitors from plants and their contribution to Alzheimer´s disease therapy [PDF]
, 2013 As acetylcholinesterase (AChE) inhibitors are an important therapeutic strategy in Alzheimer's disease, efforts are being made in search of new molecules with anti-AChE activity.
Alza, Natalia Paola +4 more
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Infraspecific Variation of Huperzine A and B in Icelandic Huperzia selago Complex [PDF]
, 2018 Publisher's version (útgefin grein)The alkaloids huperzine A and huperzine B were originally isolated from the Chinese club moss Huperzia serrata.
Deng, Tao +7 more
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A review study on medicinal plants affecting amnesia through cholinergic system [PDF]
, 2012 Neurotransmitter modification is an important method for the treatment of memory loss or amnesia. Cholinomimetic drugs, particularly, acetylcholine esterase inhibitors are the mainstream in pharmacotherapy of amnesia. Donepezil, tacrine, galantamine, and
Baradaran, Azar. +3 more
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Nomenklatorisch-taxonomische Änderungen in der 16. Auflage der von W. Rothmaler begründeten Exkursionsflora von Deutschland [PDF]
, 2012 1996 ist die 16. Auflage des zweiten Bandes der Exkursionsflora erschienen (ROTHMALER 1996). Verschiedene Kapitel dieses Bandes wurden umfassend überarbeitet oder neu erstellt. Zahlreiche für Deutschland neue Arten wurden aufgenommen und in die Schlüssel
Braun, Uwe
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Isolation and characterization of endophytic huperzine A-producing fungi from Huperzia serrata
Journal of Industrial Microbiology & Biotechnology, 2010 Huperzia serrata is a producer of huperzine A (HupA), a cholinesterase inhibitor (ChEI). Over 120 endophytic fungi were recovered from this plant and screened for Hup-A and nine were found. These nine represented seven different fungal genera with the most significant producer being Shiraia sp. A total of 127 endophytic fungi isolates obtained from the
Ya, Wang +5 more
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International Journal of Systematic and Evolutionary Microbiology, 2016 A novel endophytic actinobacterium, designated strain CPCC 204076T, was isolated from surface-sterilized tissue of the medicinal plant Huperzia serrata (Thunb.) collected from Sichuan Province, south-west China. The taxonomic position of the isolate was investigated by a polyphasic approach.
Zhi-Lian, Gong +5 more
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Anti-neuroinflammatory effects of alkaloid-enriched extract from Huperzia serrata on lipopolysaccharide-stimulated BV-2 microglial cells. [PDF]
Pharm Biol, 2023 Dang TK +8 more
europepmc +1 more source
The temporal and spatial endophytic fungal community of Huperzia serrata: diversity and relevance to huperzine A production by the host. [PDF]
BMC Microbiol, 2022 Shen Z +8 more
europepmc +1 more source
Diversity of endophytic fungal community in Huperzia serrata from different ecological areas and their correlation with Hup A content. [PDF]
BMC Microbiol, 2022 Pang B +10 more
europepmc +1 more source