Results 111 to 120 of about 4,065 (149)
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Hutchinson-Gilford progeria syndrome
Drugs of the Future, 2006The rare genetic autosomal dominant condition Hutchinson-Gilford progeria syndrome (HGPS) is characterized by a dramatic, rapid appearance of aging beginning in childhood. HGPS progression generates vascular disease, which generally leads to death during the teenage years.
null Davies, S.L., null Bozzo, J.
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Cardiovascular manifestations of Hutchinson–Gilford progeria syndrome
Cardiology in the Young, 2022AbstractCardiovascular complications are the most frequent cause of death in patients with the Hutchinson–Gilford progeria syndrome. However, due to its rarity, studying the course of cardiac abnormalities has been a challenge. The cardiovascular phenotype helps to provide greater insight into the natural history of these abnormalities.
Andreia Palma +2 more
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Hutchinson–Gilford Progeria Syndrome
JAMA DermatologyThis case report describes a boy younger than 2 years with Hutchinson–Gilford progeria syndrome.
Yu-Ting, Tsai, Yi-Chien, Yang
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Hutchinson-Gilford Progeria Syndrome
2019The Hutchinson-Gilford syndrome or progeria is a laminopathy generated by mutations that affect LMNA gene. This produces an abnormal protein named progerine which alters the formation of the cellular membrane inducing premature aging of all cells. In the present review aspects related to the pathophysiology and clinical characteristics of this syndrome
Camacho-Cruz, Jhon +12 more
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Patient with unusual Hutchinson-Gilford syndrome (progeria)
Pediatric Neurology, 1994A patient with unusual Hutchinson-Gilford syndrome (progeria) is reported. This 7-year-old boy had all the characteristics of progeria, except for coxa valga and the "horse-riding" stance. A previous cerebral infarction was detected in the right putamen on cranial magnetic resonance imaging.
S, Matsuo +4 more
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HUTCHINSON-GILFORD PROGERIA SYNDROME: A PATHOLOGIC STUDY
Pediatric Pathology & Molecular Medicine, 2002Hutchinson-Gilford progeria syndrome is an extremely rare condition with features of premature and accelerated aging. The pattern of inheritance if unclear, although both autosomal recessive and autosomal dominant modes have been proposed. The children usually present in late infancy and early childhood with a characteristic phenotype of alopecia ...
Jeanne, Ackerman, Enid, Gilbert-Barness
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Hutchinson-Gilford progeria syndrome.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1999Hutchinson-Gilford progeria syndrome is an extremely rare condition of premature aging. It is characterized by growth retardation and accelerated degenerative changes of cutaneous, musculoskeletal and cardiovascular systems. The pathogenesis of the disease is unknown. The patients usually appear normal at birth. Typical manifestations develop gradually
W, Wisuthsarewong, S, Viravan
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Hutchinson-Gilford Progeria Syndrome
Southern Medical Journal, 1978P, Runge +3 more
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Hip Disease in Hutchinson-Gilford Progeria Syndrome
Journal of Pediatric Orthopaedics, 1984Two cases of Hutchinson-Gilford progeria syndrome are presented with a focus on hip disease. A severe coxa valga is the first abnormality. The femoral head becomes increasingly uncovered as the acetabulum becomes more dysplastic. The center edge angle decreases, the acetabular index increases, and the medial wall of the acetabulum widens.
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