Results 91 to 100 of about 27,059 (274)

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Critical importance of appropriate fixation conditions for faithful imaging of receptor microclusters

Biology Open, 2016
Receptor clustering is known to trigger signalling events that contribute to critical changes in cellular functions. Faithful imaging of such clusters by means of fluorescence microscopy relies on the application of adequate cell fixation methods prior ...
Tess A. Stanly, Marco Fritzsche, Suneale Banerji, Esther García, Jorge Bernardino de la Serna, David G. Jackson, Christian Eggeling   +6 more
doaj   +1 more source

Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury

Med Research, EarlyView.
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang, Yuying Mo, Zhishan Ling, Yuting Zeng, Qi Zhang, Shuqi Zheng, Shuyang Wen, Yupeng Xiao, Siying Long, Tingting Yang, Qianru Li, Wenjie Shi, Guozhi Huang, Qing Zeng   +13 more
wiley   +1 more source

Preparation, Characterization, and Inhibition of Hyaluronic Acid Oligosaccharides in Triple-Negative Breast Cancer

Biomolecules, 2019
Hyaluronic acid (hyaluronan, HA) is a critical component of the extracellular matrix and plays an important biological function of interacting with different molecules and receptors.
Wenwei Han, Lili Song, Yingdi Wang, Youjing Lv, Xiangyan Chen, Xia Zhao   +5 more
doaj   +1 more source

Nuclear factor-κB activation by type II collagen peptide in articular chondrocytes: its inhibition by hyaluronan via the receptors [PDF]

, 2013
Tadashi Yasuda
openalex   +1 more source

Supplementary Figure 5 from TGFβ and Hippo Pathways Cooperate to Enhance Sarcomagenesis and Metastasis through the Hyaluronan-Mediated Motility Receptor (HMMR)

, 2023
Shuai Ye, Ying Liu, Ashley M. Fuller, Rohan Katti, Gabrielle E. Ciotti, Susan Chor, Md. Zahidul Alam, Samir Devalaraja, Kristin Lorent, Kristy Weber, Malay Haldar, Michael Pack, T.S. Karin Eisinger‐Mathason   +12 more
openalex   +1 more source

Signaling Properties of Hyaluronan Receptors [PDF]

Journal of Biological Chemistry, 2002
Eva A, Turley, Paul W, Noble, Lilly Y W, Bourguignon   +2 more
openaire   +2 more sources

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

Sperm Separation and Selection Techniques to Mitigate Sperm DNA Damage

Life
Semen preparation and sperm selection techniques exploit the morphological and physiological characteristics of sperm function, including motility, morphology, density, and maturity, as reflected by their cell-surface charge and the expression of ...
Steven Fleming, David Morroll, Martine Nijs   +2 more
doaj   +1 more source

Crohn’s Disease Fibroblasts Overproduce the Novel Protein KIAA1199 to Create Proinflammatory Hyaluronan FragmentsSummary

Cellular and Molecular Gastroenterology and Hepatology, 2016
Background & Aims: Crohn’s Disease (CD) is a chronic inflammatory disease of the gastrointestinal tract. Fibrosis, a serious complication of CD, occurs when activated intestinal fibroblasts deposit excessive amounts of extracellular matrix (ECM) in ...
Artin Soroosh, Sami Albeiroti, Gail A. West, Belinda Willard, Claudio Fiocchi, Carol A. de la Motte   +5 more
doaj   +1 more source