Layilin, a Novel Integral Membrane Protein, Is a Hyaluronan Receptor [PDF]
The actin cytoskeleton plays a significant role in changes of cell shape and motility, and interactions between the actin filaments and the cell membrane are crucial for a variety of cellular processes. Several adaptor proteins, including talin, maintain the cytoskeleton-membrane linkage by binding to integral membrane proteins and to the cytoskeleton.
Jonathan M.G. Higgins+3 more
openaire +3 more sources
This review systematically examines the nanomechanical mechanisms of mussel‐inspired molecular interactions, primarily investigated by direct force measurement techniques such as surface forces apparatus and atomic force microscopy. The macroscopic adhesive and self‐healing performances of mussel‐inspired functional materials, including coacervates ...
Pan Huang, Hongjian Zhang, Hongbo Zeng
wiley +1 more source
Supra and subgingival application of antiseptics or antibiotics during periodontal therapy
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero+5 more
wiley +1 more source
Hyaluronic acid alters vessel behavior in CXCL12-treated HUVECs [PDF]
Hyaluronic acid (HA) is a key component of the extracellular matrix known for absorbing water, swelling, and altering solid stress of tumors. HA’s anionic behavior may provide important biochemical effects toward tumor progression as well.
Seibel, Alex J.
core
Inducers of epithelial mesenchymal transition and cancer stem cells in malignant pleural effusions [PDF]
The Epithelial to Mesenchymal Transition (EMT) plays a role not only in tumor metastasis but also in tumor recurrence. This process is believed to be tightly linked to the presence of Cancer Stem Cells (CSCs) however, it is still not clear which ...
Cherubini, Emanuela+5 more
core +1 more source
Dissecting the role of hyaluronan synthases in the tumor microenvironment
The tumor microenvironment is becoming a crucial factor in determining the aggressiveness of neoplastic cells. The glycosaminoglycan hyaluronan is one of the principal constituents of both the tumor stroma and the cancer cell surfaces, and its ...
A. Passi+3 more
semanticscholar +1 more source
Biomimetic Cell Membrane‐Coated Scaffolds for Enhanced Tissue Regeneration
This review examines the development and use of cell membrane‐coated scaffolds in tissue engineering. Bioinspired phospholipid and glycocalyx coatings enhance anti‐fouling, anti‐thrombogenic, and selective molecular recognition properties. Native cell membrane coatings further support cell‐specific interactions, immune modulation, and reduced bacterial
Carmen Alvarez‐Lorenzo+5 more
wiley +1 more source
Hyaluronan, a Crucial Regulator of Inflammation
Hyaluronan (HA), a major component of the extracellular matrix (ECM), plays a key role in regulating inflammation. Inflammation is associated with accumulation and turnover of hyaluronan polymers by multiple cell types. Increasingly through the years, HA
Aaron C Petrey, Carol A. de la Motte
doaj +1 more source
Responsive Polyelectrolyte Brushes in Applications: Functions, Stimuli, and Design Considerations
With advances in the synthesis of polyelectrolyte brushes, these coatings of surface‐grafted chains find uses in an increasing number of applications. This review summarizes three core aspects of these brushes: how they introduce functionality to surfaces; how external stimuli influence their properties; and what practical considerations should be ...
Leon A. Smook+3 more
wiley +1 more source
From secretome analysis to immunology: chitosan induces major alterations in the activation of dendritic cells via a TLR4-dependent mechanism [PDF]
Dendritic cells are known to be activated by a wide range of microbial products, leading to cytokine production and increased levels of membrane markers such as major histocompatibility complex class II molecules.
Arora+42 more
core +5 more sources