Results 101 to 110 of about 2,309,824 (325)
Hyaluronic Acid (HA) Receptors and the Motility of Schwann Cell(-Like) Phenotypes
Cells, 2020 The cluster of differentiation 44 (CD44) and the hyaluronan-mediated motility receptor (RHAMM), also known as CD168, are perhaps the most studied receptors for hyaluronic acid (HA); among their various functions, both are known to play a role in the ...
Sihem Ouasti +5 more
doaj +1 more source
Advanced Therapeutics, EarlyView.Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi +5 more
wiley +1 more source
SARS-CoV Regulates Immune Function-Related Gene Expressions in Human Monocytic Cells [PDF]
, 2011 Background: Severe Acute Respiratory Syndrome (SARS) is characterized by acute respiratory distress (ARDS) and pulmonary fibrosis, and the monocyte/macrophage is the key player in the pathogenesis of SARS. Methods: In this study, we ...
Betty A. Wu-Hsieh +4 more
core +1 more source
Advanced Science, EarlyView.This study defines the structure, mechanics, and mechanobiology of the fibrocartilage pericellular matrix (PCM) using the murine meniscus, showing how collagen V deficiency alters PCM properties and disrupts cell mechanosensitive signaling. Findings emphasize the critical role of PCM in fibrocartilage mechanobiology and suggest targeting it can enhance
Chao Wang +13 more
wiley +1 more source
Utilization of Glycosaminoglycans/Proteoglycans as Carriers for Targeted Therapy Delivery
International Journal of Cell Biology, 2015 The outcome of patients with cancer has improved significantly in the past decade with the incorporation of drugs targeting cell surface adhesive receptors, receptor tyrosine kinases, and modulation of several molecules of extracellular matrices (ECMs ...
Suniti Misra +5 more
doaj +1 more source
Frontiers in Neurology, 2014 Traumatic brain injury triggers many secondary changes in tissue biology which ultimately determine the extent of injury and clinical outcome. Hyaluronan (hyaluronic acid, HA) is a protective cementing gel present in the intercellular spaces whose ...
Guoqiang eXing, Ming eRen, Ajay eVerma
doaj +1 more source
Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives
Advanced Science, EarlyView.Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu +13 more
wiley +1 more source
Advanced Science, EarlyView.A hollow nanomotor (PM‐HMSN/Arg) propelled by ultrasound‐triggered nitric oxide (NO) was developed. The nanomotor employs a “tethering‐relaxing‐drilling” mechanism to overcome biological barriers, enabling multimodal theranostics of cancer with deep penetration and extended lifetime.
Xue Xu +7 more
wiley +1 more source
Studies on the sperm reservoir of the pig oviduct [PDF]
, 2003 During sperm transport in the female pig a proportion of spermatozoa are arrested, often for 24 h or more, in a particular segment of the utero-tubal junction (UTJ) and the adjacent tubal isthmus, where a sperm reservoir (SR) is built up.
Tienthai, Paisan
core
ECRG4 regulates neutrophil recruitment and CD44 expression during the inflammatory response to injury. [PDF]
, 2020 The complex molecular microenvironment of the wound bed regulates the duration and degree of inflammation in the wound repair process, while its dysregulation leads to impaired healing. Understanding factors controlling this response provides therapeutic
Baird, Andrew +5 more
core