Results 101 to 110 of about 27,059 (274)

Systematic Analysis of the Clinical Significance of Hyaluronan-Mediated Motility Receptor in Colorectal Cancer [PDF]

open access: gold, 2021
Yanping Tang   +6 more
openalex   +1 more source

Hyaluronan receptor-directed assembly of chondrocyte pericellular matrix. [PDF]

open access: yesThe Journal of cell biology, 1993
Initial assembly of extracellular matrix occurs within a zone immediately adjacent to the chondrocyte cell surface termed the cell-associated or pericellular matrix. Assembly within the pericellular matrix compartment requires specific cell-matrix interactions to occur, that are mediated via membrane receptors.
openaire   +2 more sources

Rapid Generation of Fusable Cell Beads for Multi‐Scale Human Living Materials Assembly

open access: yesSmall Methods, EarlyView.
Living beads are produced through the combination of metabolic glycoengineering, click chemistry, and superhydrophobic surfaces, to develop a spheroid alternative for bottom‐up tissue engineering and disease modeling. The living beads present a size independent of cell density and a rapid fabrication methodology, providing a platform that can fuse into
Beatriz S. Moura   +5 more
wiley   +1 more source

Eplerenone improves kidney function and cardiac performance in obese male mice. [PDF]

open access: yesDiabet Med
Abstract Aims Renin‐angiotensin‐aldosterone system (RAAS) activation mediates obesity‐associated cardiorenal dysfunction. Due to an incomplete understanding of the molecular mechanisms, the clinical use of RAAS antagonism in obesity‐associated cardiometabolic complications remains uncertain.
Banah AK   +8 more
europepmc   +2 more sources

Pathogenesis of Vitiligo: Integrating Immune and Non‐Immune Cell Crosstalk

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Vitiligo is an acquired autoimmune disease characterized by depigmented macules resulting from melanocyte loss. It is a complex multifactorial disorder in which genetic predisposition is combined with environmental factors; however, its detailed etiology remains unclear.
Shintaro Inoue
wiley   +1 more source

Hyaluronic acid metabolism and chemotherapy resistance: recent advances and therapeutic potential

open access: yesMolecular Oncology
Hyaluronic acid (HA) is a major component of the extracellular matrix, providing essential mechanical scaffolding for cells and, at the same time, mediating essential biochemical signals required for tissue homeostasis.
Zhanhong Liu   +6 more
doaj   +1 more source

Vasoreactivity as a Measure of Kidney Viability During Ex Vivo Normothermic Machine Perfusion

open access: yesArtificial Organs, EarlyView.
This study aimed to investigate the influence of warm ischemic injury on renal vascular responsiveness to vasoactive drugs during normothermic machine perfusion (NMP). We found that the vascular responses to dopamine and norepinephrine could be used as objective indicators to assess kidney viability during NMP.
Isa M. van Tricht   +4 more
wiley   +1 more source

Equine experimental lameness induction models

open access: yesEquine Veterinary Education, EarlyView.
Summary Equine lameness due to musculoskeletal injury remains a common and significant cause of decreased performance. While our understanding and management of lameness have improved with advanced imaging, as well as diagnostic and therapeutic progression, a need for experimental equine models of lameness remains.
A. Dockery, B. Beasley, V. J. Moorman
wiley   +1 more source

Impacts of Hyaluronan on Extracellular Vesicle Production and Signaling

open access: yesCells
Hyaluronan (HA) is a critical component of cell and tissue matrices and an important signaling molecule. The enzymes that synthesize and process HA, as well as the HA receptors through which the signaling properties of HA are transmitted, have been ...
Melanie A. Simpson
doaj   +1 more source

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