Importance of hyaluronan biosynthesis and degradation in cell differentiation and tumor formation
Hyaluronan is an important connective tissue glycosaminoglycan. Elevated hyaluronan biosynthesis is a common feature during tissue remodeling under both physiological and pathological conditions.
P. Heldin
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Expression of human hyaluronan synthases in response to external stimuli [PDF]
A. Jacobson+4 more
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This data article provides gene expression profiles, determined by using real-time PCR, of fibroblasts and keratinocytes treated with 0.01% and 0.001% extracts of holy basil plant (Ocimum tenuiflorum), sri lankan local name “maduruthala”, 0.1% and 0.01 ...
Takao Someya+5 more
doaj
Topological Organization of the Hyaluronan Synthase fromStreptococcus pyogenes [PDF]
Coy D. Heldermon+2 more
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Differential effects of hyaluronan synthase 3 deficiency after acute vs chronic liver injury in mice
BackgroundHyaluronan (HA) is a ubiquitous extracellular matrix (ECM) glycosaminoglycan synthesized by three different enzymes, hyaluronan synthase (HAS)1, 2, and 3. HA synthesis mediated by HAS3 promotes inflammation and is pathogenic in animal models of
Jennifer M. McCracken+4 more
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Hyaluronan Synthase Elevation in Metastatic Prostate Carcinoma Cells Correlates with Hyaluronan Surface Retention, a Prerequisite for Rapid Adhesion to Bone Marrow Endothelial Cells [PDF]
Melanie A. Simpson+6 more
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Pro-Hyp-CONH-GlcN (POGlcN) is a glycopeptide synthesized from a typical bioavailable collagen peptide Pro-Hyp by conjugation with glucosamine. This study investigated the effects of POGlcN on dermal fibroblast growth, hyaluronan production, and the ...
Mengmeng Feng, Mirko Betti
doaj
The role of hyaluronan (HA), serum-derived HA-associated protein (SHAP)-HA complex and hyaluronan synthase (HAS) in endometrial carcinomas was investigated.
Hiromitsu Yabushita+7 more
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Epidermal Growth Factor Activates Hyaluronan Synthase 2 in Epidermal Keratinocytes and Increases Pericellular and Intracellular Hyaluronan [PDF]
Juha-Pekka Pienimäki+9 more
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Decreased expression of hyaluronan synthase and loss of hyaluronan-rich cells in the anterior tibial fascia of the rat model of chemotherapy-induced peripheral neuropathy. [PDF]
Wang R+5 more
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