Results 81 to 90 of about 10,179 (169)

Investigation of Hyaluronan Synthase 2 and CD44 immune reactivity as a biomarker to predict Progesterone-Resistant Endometrial Hyperplasia without atypia: A retrospective case-control study

Indian Journal of Pathology and Microbiology
Background/Aims: In our study, the effect of hyaluronan synthase 2 (HAS2) and CD44 immunoreactivity as a predictive biomarker in the prediction of progesterone-resistant endometrial hyperplasia (EH) cases without atypia was investigated.
Emine Boybay, Remzi Atilgan, Şehmus Pala, Tuncay Kuloğlu, Gökhan Artaş   +4 more
doaj   +1 more source

Cartilage-Specific Has2 Deletion Uncovers an Important Role for Hyaluronan in Cartilage and Joint Integrity

Biomedicines
Background: Hyaluronan (HA) is a critical extracellular matrix component that we have demonstrated to be important for embryonic endochondral bone formation and postnatal synovial joint formation, supporting normal articular cartilage (AC) architecture ...
Yingcui Li, Raymond Xue, Sean Congdon, Maria Abbazia, Tianhui Zhou, Tiffiny Wong, Kyle Vaccaro, Kemar Edwards, Alexander Tress, Riley Stevens, Yu Yamaguchi, Kevin W.-H. Lo   +11 more
doaj   +1 more source

Dual inhibition of FAS and HAS2/3 by 4-MU in Realgar-Coptis chinensis unveils a metabolic checkpoint for liver cancer therapy

Natural Products and Bioprospecting
Modern pharmacology has found that both Realgar and Coptis chinensis can induce apoptosis in tumor cells, and traditional Chinese medicine theory suggests the possibility of combining the two, however, the specific mechanisms involved have not been ...
Songtao Wu, Yingying Wang, Denghui Deng, Guohua Zheng, Hanxiang Mei, Cong Wang, Xiang Zheng, Chun Gui, Fei Liao, Meixian Xiang   +9 more
doaj   +1 more source

Clinicopathological Role of Serum-Derived Hyaluronan-Associated Protein (SHAP)-Hyaluronan Complex in Endometrial Cancer

Obstetrics and Gynecology International, 2011
The role of hyaluronan (HA), serum-derived HA-associated protein (SHAP)-HA complex and hyaluronan synthase (HAS) in endometrial carcinomas was investigated.
Hiromitsu Yabushita, Keita Iwasaki, Kouhei Kanyama, Yukihiko Obayashi, Lisheng Zhuo, Naoki Itano, Koji Kimata, Akihiko Wakatsuki   +7 more
doaj   +1 more source

Decreased expression of hyaluronan synthase and loss of hyaluronan-rich cells in the anterior tibial fascia of the rat model of chemotherapy-induced peripheral neuropathy. [PDF]

Pain Rep, 2023
Wang R, Matsuoka Y, Sue N, Nakatsuka K, Tsuboi C, Morimatsu H.   +5 more
europepmc   +1 more source

CPAP-induced airway hyper-reactivity in mice is modulated by hyaluronan synthase-3. [PDF]

Pediatr Res, 2022
Mayer CA, Ganguly A, Mayer A, Pabelick CM, Prakash YS, Hascall VC, Midura RJ, Cali V, Flask CA, Erokwu BO, Martin RJ, MacFarlane PM.   +11 more
europepmc   +1 more source

Hyaluronan Synthase 1: A Novel Candidate Gene Associated With Late-Onset Non-syndromic Hereditary Hearing Loss. [PDF]

Clin Exp Otorhinolaryngol, 2022
Umugire A, Lee S, Lee CJ, Choi Y, Kim T, Cho HH.   +5 more
europepmc   +1 more source

Epigenetic Regulation of Hyaluronan-Associated Genes in the Brain: Identifying Key Regulatory Sites

Epigenomes
Hyaluronan (HA) is a ubiquitous extracellular matrix (ECM) component that is gaining significant attention for its diverse roles in cell signalling and disease.
Rosalyn E. Acevedo, Esther Walton, Karen R. Mifsud   +2 more
doaj   +1 more source

An Engineered Hyaluronan Synthase [PDF]

Journal of Biological Chemistry, 2004
Hiroko Hoshi, Hiroaki Nakagawa, Susumu Nishiguchi, Kazumichi Iwata, Kenichi Niikura, Kenji Monde, Shin-Ichiro Nishimura   +6 more
openaire   +1 more source

Elevation of Hyaluronan Synthase by Magnesium Supplementation Mediated through the Activation of GSK3 and CREB in Human Keratinocyte-Derived HaCaT Cells. [PDF]

Int J Mol Sci, 2021
Marunaka K, Shu S, Kobayashi M, Goto M, Katsuta Y, Yoshino Y, Ikari A.   +6 more
europepmc   +1 more source