Background: Pulmonary hypertension (PH) is a devastating and progressive disease characterized by excessive proliferation of pulmonary artery smooth muscle cells (PASMCs) and remodeling of the lung vasculature.
Tinne C. J. Mertens +20 more
doaj +1 more source
Hyaluronan synthase 2, a target of miR-200c, promotes carbon tetrachloride-induced acute and chronic liver inflammation via regulation of CCL3 and CCL4. [PDF]
Kim SM +7 more
europepmc +1 more source
Jatrorrhizine is one of the major bioactive compounds found in Phellodendron amurense. Previous studies have reported various health benefits of jatrorrhizine, but little is known about its effect on skin health.
Junhyo Cho
doaj +1 more source
Photoaging Protective Effects of Quercitrin Isolated from ‘Green Ball’ Apple Peel
Premature skin aging, also known as photoaging, refers to the changes in the structure and function of the skin caused by chronic sun exposure. The ultraviolet radiation in sunlight is one of the key factors that cause photoaging.
Eun-Ho Lee, Junhyo Cho, In-Kyu Kang
doaj +1 more source
Prognostic value of midkine, syndecan-1, hyaluronan synthase-2, sestrin-1, laminin subunit alpha-4 and fibulin-3 for malignant pleural mesothelioma. [PDF]
Akgun H +6 more
europepmc +1 more source
Maple water (Acer saccharum sap) is a traditional seasonal beverage consumed in North America; however, its functional relevance as a bioactive dietary resource remains poorly understood.
Ye-Lim You +4 more
doaj +1 more source
Fibroblasts as key effectors of acupuncture in treatment of rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation, cartilage degradation, and bone erosion. The diseases also involves pathological changes in the surrounding fascial tissues that lead to persistent pain ...
Shi-Wei Tu +35 more
doaj +1 more source
Transcriptional regulation of the human hyaluronan synthase genes: focus on hyaluronan synthase 2 [PDF]
This thesis examines the transcriptional regulation of the human hyaluronan synthase (HAS) genes, with particular focus on hyaluronan synthase 2. The data details the reconstruction of the genomic structures of each HAS isoform for the first time, as well as analysis of the activity of each HAS proximal promoter.
openaire
Emodin regulates cell cycle of non-small lung cancer (NSCLC) cells through hyaluronan synthase 2 (HA2)-HA-CD44/receptor for hyaluronic acid-mediated motility (RHAMM) interaction-dependent signaling pathway. [PDF]
Li M, Jin S, Cao Y, Xu J, Zhu S, Li Z.
europepmc +1 more source

