Results 1 to 10 of about 853 (113)

Role of the WOR1 Promoter of Candida albicans in Opaque Commitment

mBio, 2021
Candida ...
Thomas P. Conway, Kayla Conway, Frank A. Boksa, Claude Pujol, Deborah Wessels, David R. Soll   +5 more
doaj   +1 more source

Detection of αB-Conotoxin VxXXIVA (αB-CTX) by ic-ELISA Based on an Epitope-Specific Monoclonal Antibody

Toxins, 2022
In view of the toxicological hazard and important applications in analgesics and cancer chemotherapeutics of αB-CTX, it is urgent to develop an accurate, effective and feasible immunoassay for the determination and analysis of αB-CTX in real samples.
Hengkun Tang, Haimei Liu, Yehong Gao, Rui Chen, Mingke Dong, Sumei Ling, Rongzhi Wang, Shihua Wang   +7 more
doaj   +1 more source

EFG1 Mutations, Phenotypic Switching, and Colonization by Clinical a/α Strains of Candida albicans

mSphere, 2020
The transcription factor EFG1 functions as a suppressor of white-to-opaque and white-to-gray switching in a/α strains of Candida albicans. In a collection of 27 clinical isolates, 4 of the 17 EFG1/EFG1 strains, 1 of the 2 EFG1/efg1 strains, and all 8 of ...
Yang-Nim Park, Kayla Conway, Claude Pujol, Karla J. Daniels, David R. Soll   +4 more
doaj   +1 more source

Application of In-Cell ELISA assay for hybridoma screening and selection of promising producers of monoclonal antibodies

Учёные записки Казанского университета: Серия Естественные науки, 2022
This study was motivated by the pressing need to obtain monoclonal antibodies (mAb) for research and medical purposes. Screening for mAb-producing hybridomas and evaluating various cell cultures requires a technique that combines the advantages of ...
I.I. Stepanova, K.A. Artemyeva, A.A. Stepanov, I.M. Bogdanova, E.A. Ponomarenko, M.N. Boltovskaya   +5 more
doaj   +1 more source

Candida albicans Double Mutants Lacking both EFG1 and WOR1 Can Still Switch to Opaque

mSphere, 2020
Candida albicans, a pervasive opportunistic pathogen, undergoes a unique phenotypic transition from a “white” phenotype to an “opaque” phenotype. The switch to opaque impacts gene expression, cell morphology, wall structure, metabolism, biofilm formation,
Yang-Nim Park, Claude Pujol, Deborah J. Wessels, David R. Soll   +3 more
doaj   +1 more source

Production of Monoclonal Antibody Anti-NS1 Induced by DENV3 Indonesian Clinical Isolate to Detect Native NS1 Antigen of all DENV Serotypes [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Dengue Virus (DENV) infection is a mosquito-borne disease, the most severe manifestation of the infection could lead to a lethal Dengue Haemorrhagic Fever (DHF) and/or Dengue Shock Syndrome (DSS).
Tika Widayanti, Beti Ernawati Dewi, Sabar Pambudi   +2 more
doaj   +1 more source

Biological, cytomorphological and karyological heterogeneity of transformed cell lines derived from domestic pig (Sus scrofa L.) organs

Ветеринария сегодня, 2023
The main advantage of transformed cell lines as compared to primary ones is that they allow generation of the stable material suitable for long-term research and practical use.
B. L. Manin, E. A. Trofimova, V. L. Gavrilova, O. S. Puzankova   +3 more
doaj   +1 more source

Roles of the Transcription Factors Sfl2 and Efg1 in White-Opaque Switching in a/α Strains of Candida albicans

mSphere, 2019
Candida albicans remains the most pervasive fungal pathogen colonizing humans. The majority of isolates from hosts are heterozygous at the mating type locus (MTLa/α), and a third of these have recently been shown to be capable of switching to the opaque ...
Yang-Nim Park, Kayla Conway, Thomas P. Conway, Karla J. Daniels, David R. Soll   +4 more
doaj   +1 more source

Establishment and Genetic Profiling of Platinum/Taxane Doublet-Resistant Cells Generated by Hybridizing Single Resistant Cells

Clinical and Experimental Obstetrics & Gynecology, 2022
Background: Current standard chemotherapy for gynecologic malignancies consists of platinum agent and taxane though, many patients experience the relapse of disease with drug resistance making the following therapy unsuccessful.
Seiji Isonishi, Rika Saito, Noriko Yamaguchi, Saburo Saito   +3 more
doaj   +1 more source

Heat shock factor 5 is essential for spermatogenesis in mice: Detected by a new monoclonal antibody [PDF]

Iranian Journal of Basic Medical Sciences, 2020
Objective(s): Here, we examined the function of our produced monoclonal antibody (mAb10C3) to recognize one of the most important members of the HEAT shock factor family, Hsf5, in embryonic development and in spermatogenic cells of adult mouse testis ...
Atefeh Hemati, Mohammad Hossein Modarressi, sedighe kolivand, Mahnaz Azarnia   +3 more
doaj   +1 more source