Results 101 to 110 of about 59,735 (325)
Aging Cell, EarlyView.Slowed relaxation and altered MERCs embody early stages of aging in muscle, and are prevented by regular exercise. ABSTRACT Sarcopenia, or age‐related muscle dysfunction, contributes to morbidity and mortality. Besides decreases in muscle force, sarcopenia is associated with atrophy and fast‐to‐slow fiber type switching, which is typically secondary to
Ryan J. Allen +9 more
wiley +1 more source
Human hybridomas constructed with antigen-specific Epstein-Barr virus-transformed cell lines.
Proceedings of the National Academy of Sciences of the United States of America, 1982 A 6-thioguanine-resistant, human lymphoblastoid B-cell line (GM1500 6TG A-11; IgG secreting) was mutagen-treated with low-level gamma-irradiation and selected for ouabain resistance.
D. Kozbor, A. Lagarde, J. Roder
semanticscholar +1 more source
Allergy, EarlyView.SCF and TSLP expression are known to drive unique immune responses leading to the onset of allergic and inflammatory diseases. Here, we describe the characterization of a novel bsAb, CDX‐622, that targets SCF and TSLP. CDX‐622 inhibits MC functions through SCF starvation and Type 2 inflammatory responses via TSLP inhibition.
Michael B. Murphy +17 more
wiley +1 more source
European Journal of Clinical Investigation, EarlyView.In a population of patients with stable CAD, circulating levels of PCSK9 are independently associated with the progression of adverse coronary plaque phenotypes, as assessed by serial coronary computed tomography angiography. At RNA‐seq analysis of whole blood, PCSK9 was linked to the expression of genes involved in the innate‐immune response.
Rosetta Ragusa +7 more
wiley +1 more source
The hybridoma-an immunochemical laser.
Clinical Chemistry, 1981 Abstract The advent of hybridoma technology has provided the immunotechnologist a finely tunable instrument that should permit a marked advance in the immunologic sciences. The ability to choose the precise antibody required and the virtually unlimited availability of easily purified antibodies have already resulted in the simultaneous ...
R Bartholomew +5 more
openaire +3 more sources
Epilepsia, EarlyView.Abstract Objective KCNB1 encodes an α‐subunit of the delayed‐rectifier voltage‐dependent potassium channel Kv2.1. De novo pathogenic variants of KCNB1 have been linked to developmental and epileptic encephalopathies (DEEs), diagnosed in early childhood and sharing limited treatment options.
Lauralee Robichon +7 more
wiley +1 more source
, 1986 The proliferative capacity of gland cells in Hydra attenuata was investigated. The results indicate that both gland cell proliferation and interstitial cell differentiation to gland cells contribute to the maintenance of the whole population.
David, Charles N., Schmidt, Tobias
core
Cell Structure and Function, 1995 A novel method of preparing hybridomas producing rat monoclonal antibodies was established. The enlarged medial iliac lymph nodes from rats injected via hind footpads with an emulsion of antigen and Freund's adjuvant were used for cell fusion.
Y. Kishiro +3 more
semanticscholar +1 more source
Journal of Anatomy, EarlyView.Myofibre size and shape were investigated in functionally distinct muscles of humans and mice using ATPase histochemistry and immunofluorescence. In both species, soleus myofibres were found to be larger, more irregularly shaped, and more heterogeneous compared to other muscles. These findings may have implications for biomedical research and potential
Casper Soendenbroe +5 more
wiley +1 more source
Development and production of rabies virus-specific monoclonal antibodies and evaluation of their neutralizing and protective potentials [PDF]
Microbes and Infectious DiseasesBackground: Rabies is a severe viral infection that causes acute encephalomyelitis and has a case fatality rate of almost 100%. There is no cure for symptomatic rabies, but post-exposure prophylaxis (PEP), which comprises vaccines and anti-rabies ...
Rafik Soliman +3 more
doaj +1 more source