Results 111 to 120 of about 45,417 (262)

Pinopsin Regulates Melatonin Production and Daily Locomotor Activity: Functional Insights From Gene‐Edited Xenopus Tadpoles

open access: yesJournal of Pineal Research, Volume 78, Issue 2, March 2026.
ABSTRACT Circadian rhythm alignment depends on environmental light detection via opsins. Pinopsin, originally identified in the pineal organ of birds and later in amphibian pineal complex and eyes, may play a role in this process, though its function has not been genetically tested.
Neda Heshami   +4 more
wiley   +1 more source

Integrated scFv identification and CAR T cell generation for AML targeting in vivo

open access: yesInternational Journal of Cancer, Volume 158, Issue 4, Page 994-1007, 15 February 2026.
What's new? Acute myeloid leukemia (AML) is a rapidly progressing blood cancer. Advancing chimeric antigen receptor (CAR) T cell therapies, particularly through rapid translation of single chain variable fragment (scFv) discovery into CAR constructs, may improve clinical outcomes, especially the development of patient individualized CAR T cells.
Yi Liu   +13 more
wiley   +1 more source

Glia Regulate the Timing of Photoreceptor Differentiation in the Drosophila Visual System

open access: yesGlia, Volume 74, Issue 2, February 2026.
Activation of EGFR signaling in sub‐retinal glia is required for timing photoreceptor differentiation in the Drosophila visual system. ILP3 and ILP6 are downstream targets of the EGFR pathway in sub‐retinal glia, which activate insulin signaling in photoreceptor precursor cells in the developing retina.
Qian Ren, Wen‐Tzu Chang, Yong Rao
wiley   +1 more source

Mitochondrial Transporter ABCB10 Protects Against Doxorubicin‐Induced Respiratory Muscle Dysfunction Independent of Changes to Diaphragm Accumulation

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Doxorubicin (DOX) is a highly effective chemotherapeutic agent whose use can cause respiratory toxicity, increasing patient fatigue and negatively impacting quality of life and survival. These adverse effects occur due to diaphragm muscle mitochondrial accumulation of DOX, where it causes reactive oxygen species production and iron ...
Ashley J. Smuder   +4 more
wiley   +1 more source

A monoclonal antibody collection for C. difficile typing ?

open access: yesGut Pathogens
Clostridioides difficile is the leading cause of antibiotic-associated diarrhea and pseudomembranous colitis in adults. Various C. difficile strains circulate currently, associated with different outcomes and antibiotic resistance profiles. However, most
Lise Hunault   +12 more
doaj   +1 more source

Induction of G1 arrest by down-regulation of cyclin D3 in T cell hybridomas. [PDF]

open access: hybrid, 1995
Shoichiro Miyatake   +7 more
openalex   +1 more source

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