Results 111 to 120 of about 59,735 (325)

Antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors. [PDF]

, 1984
The present study examines the ability of hapten-specific murine splenic B lymphocytes to present hapten-proteins to carrier-specific T cell hybridomas.
Abbas, AK, Benacerraf, B, Rock, KL
core  

An antibody raised against a pathogenic serpin variant induces mutant-like behaviour in the wild-type protein. [PDF]

, 2015
A monoclonal antibody (mAb) that binds to a transient intermediate may act as a catalyst for the corresponding reaction; here we show this principle can extend on a macro-molecular scale to the induction of mutant-like oligomerisation in a wild-type ...
Faull, SV, Haq, I, Irving, JA, Kotov, VR, Lomas, DA, Miranda, E, Motamedi-Shad, N, Perez, J   +7 more
core   +1 more source

V region gene analysis of anti-Sm hybridomas from MRL/Mp-lpr/lpr mice.

Journal of Immunology, 1993
Anti-Sm autoantibodies are unique to SLE, but are present in only 25% of patients with this disease. This response also occurs at a similar frequency in mice of the autoimmune MRL strains.
D. Bloom, J. Davignon, M. Retter, M. Shlomchik, David S. Pisetsky, Philip L. Cohen, Robert A. Eisenberg, Stephen H. Clarke   +7 more
semanticscholar   +1 more source

Myocellular adaptations to short‐term weighted wheel‐running exercise are largely conserved during C26‐tumour induction in male and female mice

Experimental Physiology, EarlyView.
Abstract This study investigated whether performing a translatable murine model of concurrent training after tumour induction affects adaptations in juvenile male and female tumour‐bearing mice. Male and female Balb/c mice were injected bilaterally with colon‐26 adenocarcinoma (C26) cells or PBS at 8 weeks of age.
Stavroula Tsitkanou, Pieter Koopmans, Calvin Peterson, Ana Regina Cabrera, Ruqaiza Muhyudin, Francielly Morena, Sabin Khadgi, Eleanor R. Schrems, Tyrone A. Washington, Kevin A. Murach, Nicholas P. Greene   +10 more
wiley   +1 more source

Development and characterization of murine monoclonal antibody specific for the P1.4 PorA proteins from strain B:4:P1.(7b).4. of Neisseria meningitidis

VacciMonitor, 2011
Neisseria meningitidis isolates are conventionally classified by serosubtyping that characterizes the reactivities of the PorA outer membrane protein variable-region epitopes with monoclonal antibodies.
María Elena Pérez, Ramón Barberá, Francisco Domínguez , Oscar Otero, Mercedes Gutiérrez, Gustavo Falero, Grethel Reyes, Franklin Sotolongo, Gustavo Sierra   +8 more
doaj  

An ultra scale-down analysis of the recovery by dead-end centrifugation of human cells for therapy. [PDF]

, 2014
An ultra scale-down method is described to determine the response of cells to recovery by dead-end (batch) centrifugation under commercially defined manufacturing conditions.
Delahaye, M, Hoare, M, Lawrence, K, Ward, SJ   +3 more
core   +1 more source

Production of autoantibodies by human-human hybridomas.

Journal of Clinical Investigation, 1982
Peripheral blood lymphocytes and splenocytes of patients with autoimmune disease were used to prepare human-human hybridomas that produce autoantibodies. Because exogenous immunization was not used, the hybridoma antibodies were derived from B cells that
Y. Shoenfeld, S. Hsu-Lin, J. Gabriels, L. Silberstein, B. Furie, B. Furie, B. Stollar, R. Schwartz   +7 more
semanticscholar   +1 more source

Presynaptic quantal size enhancement counteracts post‐tetanic release depression

The Journal of Physiology, EarlyView.
Abstract figure legend Sustained high‐frequency stimulation decreases the number of synaptic vesicles that fuse per action potential at the Drosophila neuromuscular junction. However, the postsynaptic response remains largely unchanged. An increased postsynaptic response to individual vesicles, likely driven by an increase in vesicle size resulting ...
Anu G. Nair, Nasrin Bollmohr, Levin Schökle, Jennifer Keim, José María Mateos Melero, Martin Müller   +5 more
wiley   +1 more source

Endogenous antigen processing drives the primary CD4+ T cell response to influenza. [PDF]

, 2015
By convention, CD4+ T lymphocytes recognize foreign and self peptides derived from internalized antigens in combination with major histocompatibility complex class II molecules.
A Sette, A Suraweera, Asha Purnima V Ganesan, AW Boyden, B Moltedo, BO Lee, CB Brooke, CC Norbury, CD O'Donnell, CT Spencer, EK Bikoff, EK Bikoff, G Sinnathamby, G Sinnathamby, JD Comber, JD Comber, JS Testa, KL Legge, Laurence C Eisenlohr, M Baz, M Gannagé, M Gannagé, M Lay, M Maric, M Roederer, MA Goldstein, Mark Mendonca, Michael A Miller, MK Tewari, MK Tewari, MT Osterholm, MY Sangster, Nancy Luckashenak, NH Shoukry, P Nair, PR Johnson Jr., R Busch, RA Langlois, RM Vabulas, S Fazekas de St. Groth, S Sanderson, T Hou, TM Wilkinson, Y Hosaka, Y Zhou   +44 more
core   +1 more source

Retinoic acids inhibit activation-induced apoptosis in T cell hybridomas and thymocytes.

Journal of Immunology, 1992
Apoptosis is induced in immature thymocytes and T cell hybridomas upon stimulation via the TCR/CD3 complex. This phenomenon appears to be related to negative selection of T cell clones in the thymus.
M. Iwata, M. Mukai, Y. Nakai, R. Iseki
semanticscholar   +1 more source