Results 121 to 130 of about 45,417 (262)

Production of CD4⁺ and CD8⁺ T cell hybridomas.

open access: yesMethods in molecular biology, 2013
D. Canaday
semanticscholar   +1 more source

Advances in Therapeutic Antibody Discovery and Development Targeting G Protein‐Coupled Receptors

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT G protein‐coupled receptors (GPCRs) are integral to numerous biological processes and are associated with various diseases across all therapeutic areas. Consequently, GPCRs present substantial potential for antibody‐based therapies. This review offers an overview of the therapeutic GPCR‐antibody target landscape and examines the diversity ...
Catherine J. Hutchings   +6 more
wiley   +1 more source

Purification and NH2-terminal amino acid sequence of a T-cell-derived lymphokine with growth factor activity for B-cell hybridomas.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1986
J. Snick   +6 more
semanticscholar   +1 more source

Aging Reshapes γ/δ T‐Cell Immunity Through a Type I Interferon–Foxo1 Axis

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Aging reshapes the peripheral γ/δ T‐cell compartment by promoting the expansion and enhanced IL‐17–driven activity of innate‐like γ/δ T cells in secondary lymphoid organs. This remodeling is controlled by type I interferon–dependent downregulation of Foxo1, linking aging to heightened pro‐inflammatory γ/δ T‐cell responses.
Aurélie Durand   +7 more
wiley   +1 more source

Rapid Glass‐Substrate Digital Light 3D Printing Enables Anatomically Accurate Stroke Patient‐Specific Carotid Artery‐on‐Chips for Personalized Thrombosis Investigation

open access: yesAdvanced Materials, Volume 38, Issue 5, 22 January 2026.
A rapid glass‐substrate 3D microfabrication method creates anatomically accurate carotid artery‐on‐a‐chip models from stroke patient scans in 2 h. These miniaturized devices replicate patient‐specific blood vessel geometry and flow patterns, enabling real‐time imaging of clot formation under controlled injury.
Yunduo Charles Zhao   +14 more
wiley   +1 more source

Quantitative Assessment of Gut and Vascular Barriers in TTOP, a Cartridge‐Based Bicompartmental Culture Platform

open access: yesAdvanced Materials Technologies, Volume 11, Issue 1, 8 January 2026.
The modular, versatile, and standardized cartridge‐based culture module allows to replicate gut and vascular barriers. Its conventional handling requirements facilitate adoption by non‐technical users, while the design allows safe manipulation and retrieval of samples for permeability assays and endpoint analysis.
Lorenzo Pietro Coppadoro   +6 more
wiley   +1 more source

Structural Characterization and AI‐Enhanced Modeling of a Broadly Neutralizing Camelid Antibody Against SARS‐CoV‐2 Variants

open access: yesAdvanced Therapeutics, Volume 9, Issue 1, January 2026.
This study characterizes a camelid antibody (B10) with potent neutralizing activity against SARS‐CoV‐2 Wildtype and Omicron variants. Through binding assays, epitope mapping, pseudovirus neutralization, and AI‐driven modeling, the antibody is shown to target conserved RBD regions in a closed Spike conformation.
Katja Hanack   +13 more
wiley   +1 more source

Immunological Detection of Newcastle Disease Viral Antigen in the Naturally Infected Chickens by Monoclonal Antibodies against Fusion-2 Protein

open access: yesJurnal Veteriner, 2014
Monoclonal antibodies (mAbs) against Fusion (F)2 protein of Newcastle disease virus (NDV) wereproduced for the detection of the viral antigen in infected chickens.
Nyoman Mantik Astawa   +1 more
doaj  

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