Results 121 to 130 of about 59,780 (293)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, Volume 19, Issue 10, Page 2833-2859, October 2025.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Purification and NH2-terminal amino acid sequence of a T-cell-derived lymphokine with growth factor activity for B-cell hybridomas.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1986
J. Snick   +6 more
semanticscholar   +1 more source

Large‐Scale Production of Transfusion‐Ready Red Blood Cells From Induced Pluripotent Stem Cells

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
A scalable, dynamic culture system is developed to produce red blood cells from induced pluripotent stem cells. It achieves high yields with up to 70% enucleation, not previously shown in dynamic systems, overcoming key limitations and enabling large‐scale production.
Eszter Varga   +13 more
wiley   +1 more source

Immunohistochemical Profile of a Conspicuously Organized Structure in the Dorsal Forebrain of the Peacock Gudgeon, Tateurndina ocellicauda

open access: yesJournal of Comparative Neurology, Volume 533, Issue 10, October 2025.
In the dorsal telencephalon of gobiiform fishes, there is a conspicuously organized structure, consisting of readily identifiable subregions that are surrounded by layers of cell bodies. Using immunohistochemistry against several antigen targets in this structure, we demonstrate that each of these subregions is characterized by its own individual ...
Ruth Gutjahr   +2 more
wiley   +1 more source

Synthesis, Conformal Analysis, and Antibody Binding of Staphylococcus aureus Capsular Polysaccharide Type 5 Oligosaccharides

open access: yesAngewandte Chemie, Volume 137, Issue 39, September 22, 2025.
A set of conjugation‐ready Staphylococcus aureus serotype 5 oligosaccharides has been generated using a stereoselective [3 + 3n] glycosylation strategy. The structures differ in chain length (up to three repeating units) and O‐ and N‐acetylation pattern.
Kitt E. Østerlid   +15 more
wiley   +2 more sources

Umbilical cord blood‐derived cytotoxic T lymphocytes target melanoma via HLA‐A2‐restricted tumour antigens

open access: yesClinical and Translational Medicine, Volume 15, Issue 10, October 2025.
Cord blood can be used as a cell bank for endogenous T‐cell therapy to treat melanoma patients. Compared with antigen‐specific T cells derived from peripheral blood, the main cell subsets of antigen‐specific T cells derived from umbilical cord blood are divided into memory effector cells, which may have a more durable anti‐tumour effect. In this study,
Jiaji Liang   +10 more
wiley   +1 more source

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