Results 11 to 20 of about 17,547 (197)

Obtención de anticuerpos monoclonales de ratón contra proteasa de cisteína 5 recombinante de Entamoeba histolytica

open access: yesRevista Mvz Cordoba, 2012
RESUMEN Objetivo. Obtener anticuerpos monoclonales de ratón contra la proteasas de cisteína 5 (EhCP5) de Entamoeba histolytica. Materiales y métodos. Se inmunizaron ratones BALB/c por vía intraperitoneal con adyuvante de Freund completo e incompleto con
Juanita Trejos S, Jhon Castaño O
doaj   +1 more source

Production and characterisation of monoclonal antibodies for the detection of AOZ, a tissue bound metabolite of furazolidone

open access: yesVeterinární Medicína, 2005
3-amino-2-oxazolidinone (AOZ) is a tissue bound toxic metabolite derived from the nitrofuran antibiotic, furazolidone. AOZ is detected in the derivatised form of 3-{[(2-nitrophenyl) methylene] amino}-2-oxa-zolidinone (NP AOZ).
M. Vass   +6 more
doaj   +1 more source

Manufacturing of hybridomas, producing monoclonal antibodies against Burkholderia mallei and Burkholderia pseudomallei antigens

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2019
Aim. Obtaining hybridomas, stable producing specific monoclonal antibodies against Burkholderia mallei and Burkholderia pseudomallei antigens. Materials and methods.
G. V. Kuklina   +7 more
doaj   +1 more source

Diversity of the antibody response to tetanus toxoid: comparison of hybridoma library to phage display library. [PDF]

open access: yesPLoS ONE, 2014
Monoclonal antibodies are important tools in research and since the 1990s have been an important therapeutic class targeting a wide variety of diseases. Earlier methods of mAb production relied exclusively on the lengthy process of making hybridomas. The
Mahsa Sorouri   +4 more
doaj   +1 more source

Development and characterization of novel chimeric monoclonal antibodies for broad spectrum neutralization of rabies virus. [PDF]

open access: yesPLoS ONE, 2017
Current post-exposure prophylaxis for rabies virus infection has several limitations in terms of supply, cost, safety, and efficacy. Attempts to replace human or equine rabies immune globulins (HRIG or ERIG) have been made by several companies and ...
Pan Kyeom Kim   +18 more
doaj   +1 more source

Novel S2 subunit-specific antibody with broad neutralizing activity against SARS-CoV-2 variants of concern

open access: yesFrontiers in Immunology, 2023
IntroductionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), had a major impact on both the global health and economy.
Chang-Kyu Heo   +9 more
doaj   +1 more source

MANUFACTURING OF HYBRIDOMAS-PRODUCERS OF MONOCLONAL ANTIBODIES TO BRUCELLOSIS AGENT ANTIGENS

open access: yesПроблемы особо опасных инфекций, 2017
Objective of study is to prepare hybridomas-producers of monoclonal antibodies to brucellosis agent antigens. Materials and methods. B. abortus, B. melitensis, B.
G. V. Kuklina   +5 more
doaj   +1 more source

Correlation between cell aggregation and antibody production in IgE-producing plasma cells

open access: yesBiochemistry and Biophysics Reports, 2017
Allergic conditions result in the increase of immunoglobulin (Ig)E-producing plasma cells (IgE-PCs); however, it is unclear how IgE production is qualitatively controlled.
Mari Hikosaka   +3 more
doaj   +1 more source

Immunogenomic engineering of a plug-and-(dis)play hybridoma platform

open access: yesNature Communications, 2016
Hybridomas are widely used for antibody screening and production due to their genetic stability and rapid proliferation. Here the authors demonstrate the rapid reprogramming of antibody specificity in hybridomas using CRISPR-Cas9.
Mark Pogson   +4 more
doaj   +1 more source

Is cancer progression caused by gradual or simultaneous acquisitions of new chromosomes?

open access: yesMolecular Cytogenetics, 2018
Background Foulds defined, “Tumor progression (as a) permanent, irreversible qualitative change in one or more of its characters” (Cancer Res. 1954).
Mathew Bloomfield, Peter Duesberg
doaj   +1 more source

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