Results 21 to 30 of about 3,489 (193)
Thermochemical Study of 1-Methylhydantoin
Using static bomb combustion calorimetry, the combustion energy of 1-methylhydantoin was obtained, from which the standard molar enthalpy of formation of the crystalline phase at T = 298.15 K of the compound studied was calculated.
Juan M. Ledo +3 more
doaj +1 more source
Hydantoin and hydrogen-bonding patterns in hydantoin derivatives [PDF]
The structure of hydantoin (imidazolidine-2,4-dione), C3H4N2O2, has been determined from a twinned crystal. The two carbonyl bond lengths are nearly equal, even though one of them adjoins electron-donating NH groups to either side while the other is adjacent to only one.
Fang-Lei, Yu +2 more
openaire +2 more sources
5-Ethoxy-1-(4-methoxyphenyl)-5-methyl-3-phenylimidazolidine-2,4-dione
The title compound is a hydantoin derivative that has been synthesized through a three-component reaction of ethyl pyruvate, p-anisidine and phenyl isocyanate.
Xabier del Corte +4 more
doaj +1 more source
l-Amino Acid Production by a Immobilized Double-Racemase Hydantoinase Process: Improvement and Comparison with a Free Protein System [PDF]
Protein immobilization is proving to be an environmentally friendly strategy for manufacturing biochemicals at high yields and low production costs. This work describes the optimization of the so-called “double-racemase hydantoinase process,” a system of
Clemente Jiménez, María José +3 more
core +3 more sources
Hydantoin (imidazolidine-2,4-dione) is a 2,4-diketotetrahydroimidazole discovered by Baeyer in 1861. Thiohydantoins and derivatives were prepared, having chemical properties similar to the corresponding carbonyl compounds.
Silvânia Maria de Oliveira +5 more
doaj +1 more source
Revisiting the SAR of the antischistosomal aryl hydantoin (Ro 13-3978) [PDF]
The aryl hydantoin 1 (Ro 13-3978) was identified in the early 1980s as a promising antischistosomal lead compound. However, this series of aryl hydantoins produced antiandrogenic side effects in the host, a not unexpected outcome given their close ...
Charman, Susan A. +13 more
core +3 more sources
Identification of a novel class of autotaxin inhibitors through cross-screening [PDF]
Three novel series were generated in order to mimic the pharmacophoric features displayed by lead compound AM095, a Lysophosphatidic acid (LPA1) receptor antagonist. Biological evaluation of this array of putative LPA1 antagonists led us to the discovery
Budd, David C. +8 more
core +1 more source
Acute Hepatic Porphyrias: Review and Recent Progress. [PDF]
The acute hepatic porphyrias (AHPs) are a group of four inherited diseases of heme biosynthesis that present with episodic, acute neurovisceral symptoms.
Andant +40 more
core +1 more source
1-Methyl-8-phenyl-1,3-diazaspiro[4.5]decane-2,4-dione
A simple, fast and cost-effective three-step synthesis of 1-methyl-8-phenyl-1,3-diazaspiro[4.5]decane-2,4-dione has been developed. The reactions described herein proceed readily, with high yields and no further purification.
Vasiliki Pardali +3 more
doaj +1 more source
Hydantoins: Synthesis, properties and anticonvulsant activity [PDF]
Hydantoin is a five-membered cyclic ureide that is present in numerous biologically active compounds including antiarrhytmics, anticonvulsants and antitumor agents. This paper describes different ways of synthesis of hydantoin-derivatives, their physical
Trišović Nemanja P. +2 more
doaj +1 more source

