Results 61 to 70 of about 3,489 (193)

Anogenital Contact Dermatitis in Spain: A REIDAC Study of Patients Undergoing Patch Testing in 2019–2024

Contact Dermatitis, Volume 94, Issue 3, Page 272-285, March 2026.
Allergic contact dermatitis is very common in patients with anogenital lesions referred for patch testing in Spain. Key allergens include fragrances, preservatives and topical treatments like anaesthetics and steroids. Emerging sensitisers including benzisothiazolinone and sodium metabisulphite are also relevant.
Mercè Grau‐Pérez, Pedro Mercader‐García, Ana María Giménez‐Arnau, Tatiana Sanz‐Sánchez, Violeta Zaragoza Ninet, Susana Córdoba Guijarro, Francisco Javier Miquel Miquel, Juan Francisco Silvestre Salvador, Ricardo González‐Pérez, Inmaculada Ruíz González, Esther Serra Baldrich, José Manuel Carrascosa, Francisco Javier Ortiz de Frutos, Mercedes Rodríguez Serna, María Elena Gatica Ortega, Carmen Paredes Suárez, Francisco José Navarro Triviño, Pablo Chicharro, Marta Andreu, Araceli Sánchez Gilo, José Juan Pereyra Rodríguez, María Antonia Pastor Nieto, Gemma Melé‐Ninot, Paloma Sánchez‐Pedreño Guillén, Enrique Gómez de la Fuente, Marta Elosua‐González, Mónica Munera‐Campos, Fátima Tous Romero, Miguel Ángel Descalzo, Leopoldo Borrego   +29 more
wiley   +1 more source

Poly(ethylene glycol)s as grinding additives in the mechanochemical preparation of highly functionalized 3,5-disubstituted hydantoins

Beilstein Journal of Organic Chemistry, 2017
The mechanochemical preparation of highly functionalized 3,5-disubstituted hydantoins was investigated in the presence of various poly(ethylene) glycols (PEGs), as safe grinding assisting agents (liquid-assisted grinding, LAG).
Andrea Mascitti, Massimiliano Lupacchini, Ruben Guerra, Ilya Taydakov, Lucia Tonucci, Nicola d’Alessandro, Frederic Lamaty, Jean Martinez, Evelina Colacino   +8 more
doaj   +1 more source

Highly Substituted 1,4‐Benzodiazepin‐2‐ones: A Rapid Modular Approach From Arynes and Unsymmetrical Imides

ChemistryEurope, Volume 4, Issue 2, February 2026.
In this work, 1,4‐benzodiazepine‐2‐ones are synthesized starting from Kobayashi‐type aryne precursors and amino acid‐derived, unsymmetrical imides. Operationally simple protocols to access both the starting materials and the potential active pharmaceutical ingredients are presented.
Jasper Mindner, Julia Gartzke, Silas Wittmer, Tassilo Segerer, Burkhard Butschke, Daniel B. Werz   +5 more
wiley   +1 more source

Structures of tribenzylmethanol and 1,2,3-triphenyl-2-propanol [PDF]

, 1993
The tribenzylmethanol molecule, (PhCH2)3COH, has approximate threefold symmetry in the solid state. The hydroxyl H atom is disordered unequally over three orientations and is not involved in hydrogen bonding.
Ferguson, George, Gallagher, John F., Glidewell, Christopher, Liles, David C., Zakaria, Choudhury M.   +4 more
core   +2 more sources

Synthesis and Biological Evaluation of 1,3,8-Triazaspiro[4.5]decane-2,4-dione Derivatives as Myelostimulators

Journal of Chemistry, 2018
Spiroconnected N-alkoxyalkylpiperidine hydantoins were obtained via the Strecker reaction of cyanohydrin with ammonium carbonate. 1,3,8-Triazaspiro[4.5]decane-2,4-diones have shown the myelostimulating activity in the artificially induced (with ...
Valentina Yu, Assel Ten, Lyailya Baktybayeva, Indira Sagatbekova, Kaldybay Praliyev, Darya Zolotareva, Tulegen Seilkhanov, Alexey Zazybin   +7 more
doaj   +1 more source

Seizure control in patients with epilepsy: the physician vs. medication factors [PDF]

, 2008
Background Little is known about the relationship between types of healthcare providers and outcomes in patients with epilepsy. This study compares the relative effects of provider type (epileptologist vs.
Jerzy P Szaflarski, Angela Y Rackley, Christopher J Lindsell, Magdalena Szaflarski, Stephen L Yates, MR Nuwer, MR Nuwer, A Catlin, AMSA, J Macinko, JZ Ayanian, JB Mitchell, A Arain, DM Ficker, WA Hauser, D Sopelana, P Seenan, N Diaz, R Kobau, K Poole, P Bradley, O Devinsky, F Gilliam, JP Szaflarski, JP Szaflarski, JO Elliott   +25 more
core   +2 more sources

Sequential Ugi reaction/base-induced ring closing/IAAC protocol toward triazolobenzodiazepine-fused diketopiperazines and hydantoins

Beilstein Journal of Organic Chemistry, 2018
A practical three-step protocol for the assembly of triazolobenzodiazepine-fused diketopiperazines and hydantoins has been developed. The synthesis of these tetracyclic ring systems was initiated by an Ugi reaction, which brought together all necessary ...
Robby Vroemans, Fante Bamba, Jonas Winters, Joice Thomas, Jeroen Jacobs, Luc Van Meervelt, Jubi John, Wim Dehaen   +7 more
doaj   +1 more source

Aryl hydantoin Ro 13-3978, a broad-spectrum antischistosomal [PDF]

, 2017
Objectives Praziquantel is the only drug available for the treatment of schistosomiasis and the state of the exhausted drug discovery pipeline is alarming.
Dong, Yuxiang, Gautam, Nagsen, Keiser, Jennifer, Panic, Gordana, Vargas, Mireille, Vennerstrom, Jonathan L., Wang, Chunkai   +6 more
core  

Protein Adductomics: Methodologies for Untargeted Screening of Adducts to Serum Albumin and Hemoglobin in Human Blood Samples. [PDF]

, 2019
The reaction products of electrophiles in vivo can be measured as adducts to the abundant proteins, hemoglobin (Hb), and human serum albumin (HSA), in human blood samples.
Carlsson, Henrik, Rappaport, Stephen, Törnqvist, Margareta   +2 more
core   +2 more sources

Synthesis of 5-bromonaphthalimide derivatives with 3-aminocycloalkanespiro-5-hydantoins [PDF]

BIO Web of Conferences
The present work reports a study on the interaction of 5-bromo-1H,3H-naphtho[1,8-cd]pyran-1,3-dione with various 3-aminocycloalkanespiro-5-hydantoins, aimed at the development of new biologically active compounds.
Marinov Marin, Nikolova Iliana, Kostova Iliana   +2 more
doaj   +1 more source