Results 1 to 10 of about 2,940 (175)

Palladium-catalyzed sulfonylative coupling of benzyl(allyl) carbonates with arylsulfonyl hydrazides

Green Synthesis and Catalysis, 2022
An efficient palladium-catalyzed sulfonylative coupling for the synthesis of benzyl(allyl) sulfones from sulfonyl hydrazides and carbonates was developed.
Bozhen Gong, Haibo Zhu, Yishuai Liu, Qian Li, Liu Yang, Guorong Wu, Qiangwen Fan, Zongbo Xie, Zhanggao Le   +8 more
doaj   +1 more source

2-([1,2,4]triazolo[1,5-c]quinazoline-2-yl-)alkyl-(alkaryl-,aryl-)-amines and their derivatives. Message 2. The synthesis of (3Н-quinazoline-4-ylidene)hydrazides N-protected aminoacids, using a variety of amine-protecting approaches. Physical-chemical prop

Zaporožskij Medicinskij Žurnal, 2018
The synthetic potential of (3H-quinazoline-4-ylidene)hydrazides of carboxylic acids is significant in the context of new s-triazoloquinazolines creation and the obtained data of biological activity is a valid reason for the development of new methods of ...
Yu. V. Martynenko, M. S. Kazunin, I. S. Nosulenko, G. G. Berest, S. І. Kоvalenko, O. M. Kamyshnyi, N. M. Polishchuk   +6 more
doaj   +1 more source

On the Nature of the Rotational Energy Barrier of Atropisomeric Hydrazides

Molecules, 2023
N-N atropisomers represent a useful class of compounds that has recently received important attention from many research groups. This article presents an in-depth analysis of the energy barrier needed for the racemization process of atropoisomeric ...
Andrea Pellegrini, Laura Marcon, Paolo Righi, Giovanni Centonze, Chiara Portolani, Marco Capodiferro, Shilashi Badasa Oljira, Simone Manetto, Alessia Ciogli, Giorgio Bencivenni   +9 more
doaj   +1 more source

Synthesis and Antibacterial Activity of New Azole, Diazole and Triazole Derivatives Based on p-Aminobenzoic Acid

Molecules, 2021
The p-aminobenzoic acid was applied for the synthesis of substituted 1-phenyl-5-oxopyrrolidine derivatives containing benzimidazole, azole, oxadiazole, triazole, dihydrazone, and dithiosemicarbazide moieties in the structure.
Birutė Sapijanskaitė-Banevič, Vykintas Palskys, Rita Vaickelionienė, Jūratė Šiugždaitė, Povilas Kavaliauskas, Birutė Grybaitė, Vytautas Mickevičius   +6 more
doaj   +1 more source

Design, Synthesis and Antitubercular Activity of Certain Nicotinic Acid Hydrazides

Molecules, 2015
Three series of 6-aryl-2-methylnicotinohydrazides 4a–i, N′-arylidene-6-(4-bromophenyl)-2-methylnicotino hydrazides 7a–f, and N′-(un/substituted 2-oxoindolin-3-ylidene)-6-(4-fluorophenyl)-2-methylnicotinohydrazides 8a–c were synthesized and evaluated for ...
Wagdy M. Eldehna, Mohamed Fares, Marwa M. Abdel-Aziz, Hatem A. Abdel-Aziz   +3 more
doaj   +1 more source

Síntese e caracterização de um novo complexo de platina (IV) a partir de seu análogo de platina (II) utilizando iodo molecular como agente oxidante: uma rota sintética interessante para obtenção de novos complexos de platina Synthesis and characterization of a novel platinum (IV) complex from its platinum (II) analogue using molecular iodine as an oxidizing agent: an interesting synthetic route for the preparation of new platinum complexes

Química Nova, 2007
In an attempt to reduce toxicity and widen the spectrum of activity of cisplatin and its analogues, much attention has been focused on designing new platinum complexes.
Wendell Guerra, Heveline Silva, Mauro Vieira de Almeida, Ana Paula Soares Fontes   +3 more
doaj   +1 more source

Different Schiff Bases—Structure, Importance and Classification

Molecules, 2022
Schiff bases are a vast group of compounds characterized by the presence of a double bond linking carbon and nitrogen atoms, the versatility of which is generated in the many ways to combine a variety of alkyl or aryl substituents. Compounds of this type
Edyta Raczuk, Barbara Dmochowska, Justyna Samaszko-Fiertek, Janusz Madaj   +3 more
doaj   +1 more source

N-Alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1-carboxamides and Their Analogues: Synthesis and Multitarget Biological Activity

Molecules, 2020
Based on the isosterism concept, we have designed and synthesized homologous N-alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1-carboxamides (from C1 to C18) as potential antimicrobial agents and enzyme inhibitors.
Martin Krátký, Zsuzsa Baranyai, Šárka Štěpánková, Katarína Svrčková, Markéta Švarcová, Jiřina Stolaříková, Lilla Horváth, Szilvia Bősze, Jarmila Vinšová   +8 more
doaj   +1 more source

Synthesis, physical-chemical properties of 2-((4-R-5-(thiophene-2-ylmethyl)-4H-1,2,4-triazole-3-yl)thio)acetohydrazides

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
Aim. Analysis of the scientific literature over the past decade has shown that large synthetic possibilities towards creating new and effective drug substances have heterocyclic compounds, in particular the derivatives of 1,2,4-triazole.
O. A. Suhak, O. I. Panasenko, Ye. G. Knysh   +2 more
doaj   +1 more source

Quinazoline-containing Hydrazydes of Dicarboxylic Acids and Products of Their Structural Modification – A Novel Class of Anti-inflammatory Agents

Acta Chimica Slovenica, 2021
The synthesis of hydrazides formed by quinazolin-4(3H)-ylidenehydrazine and dicarboxylic acids, as well as their further modification are described in the present manuscript.
Nataliia Krasovska, Viktor Stavytskyi, Inna Nosulenko, Oleksandr Karpenko, Oleksii Voskoboinik, Serhii Ivanovych Kovalenko   +5 more
doaj   +1 more source