Results 21 to 30 of about 18,659 (282)

1,3-Dipolar cycloadditions of azomethine imines [PDF]

, 2015
Azomethine imines are considered 1,3-dipoles of the aza-allyl type which are transient intermediates and should be generated in situ but can also be stable and isolable compounds.
Nájera, Carmen, Sansano, Jose M., Yus, Miguel   +2 more
core   +3 more sources

N-Alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1-carboxamides and Their Analogues: Synthesis and Multitarget Biological Activity

Molecules, 2020
Based on the isosterism concept, we have designed and synthesized homologous N-alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1-carboxamides (from C1 to C18) as potential antimicrobial agents and enzyme inhibitors.
Martin Krátký, Zsuzsa Baranyai, Šárka Štěpánková, Katarína Svrčková, Markéta Švarcová, Jiřina Stolaříková, Lilla Horváth, Szilvia Bősze, Jarmila Vinšová   +8 more
doaj   +1 more source

Different Schiff Bases—Structure, Importance and Classification

Molecules, 2022
Schiff bases are a vast group of compounds characterized by the presence of a double bond linking carbon and nitrogen atoms, the versatility of which is generated in the many ways to combine a variety of alkyl or aryl substituents. Compounds of this type
Edyta Raczuk, Barbara Dmochowska, Justyna Samaszko-Fiertek, Janusz Madaj   +3 more
doaj   +1 more source

The alpha-effect in cyclic secondary amines: new scaffolds for iminium ion accelerated transformations [PDF]

, 2009
Five-membered secondary amine heterocycles containing an α-heteroatom were prepared and shown to be ineffective as catalysts for the iminium ion catalysed Diels–Alder reaction between cinnamaldehyde and cyclopentadiene.
Cavill, Julie L., Elliott, Richard L., Evans, Gareth, Gibbs, Timothy J. K., Jones, Ian L., Platts, James A, Porzelle, Achim, Tomkinson, Nick   +7 more
core   +1 more source

Исследование связи "структура - противомикробная активность" с использованием молекулярного докинга в ряду замещенных амидов и гидразидов n-ароил-5-бром (5-хлор) антраниловых кислот [PDF]

, 2018
Изучение связи "структура - противомикробная активность" в отношении кишечной палочки (E. Coli) с использованием молекулярного докинга в ряду замещенных амидов и гидразидов N-ароил 5-бром (5-хлор) антраниловых ...
Андрюков, К. В., Коркодинова, Л. М.   +1 more
core   +2 more sources

Synthesis and Quantitative Structure–Activity Relationship of Imidazotetrazine Prodrugs with Activity Independent of O6-Methylguanine-DNA-methyltransferase, DNA Mismatch Repair and p53. [PDF]

, 2013
The antitumor prodrug Temozolomide is compromised by its dependence for activity on DNA mismatch repair (MMR) and the repair of the chemosensitive DNA lesion, O6-methylguanine (O6-MeG), by O6-methylguanine-DNA-methyltransferase (EC 2.1.1.63, MGMT). Tumor
Arris C. E., Arrowsmith J., Barvaux V. A., Boberg F., Boyd M. R., Bunz F., Damera K., Darkes M. J. M., De K., Denny B. J., Dimitrios Pletsas, Dinca E. B., Elrashied A. E. Garelnabi, Garelnabi E. A. E., Hirose Y., Honnalli S. S., Judson P. L., Karran P., Karran P., Kotera M., Leteurtre F., Li Li, Liu L., McElhinney R. S., McGarrity J. F., Mladek A. C., Nishizuka S., Pletsas D., Richard T. Wheelhouse, Roger M. Phillips, Sarkaria J. N., Schmidt B. F., Schmiedekamp A., Shealy Y. F., Siddiqui A. A., Smith R. H., Stevens M. F. G., Svilar D., Wang Y., Wheelhouse R. T., Wheelhouse R. T., Zhang J., Zhang J.   +42 more
core   +1 more source

Study on the synthesis of novel 5-substituted 2-[2-(pyridyl)ethenyl]-1,3,4-oxadiazoles and their acid–base interactions [PDF]

, 2014
: A series of novel 5-substituted 2-[2-(pyridyl)ethenyl]-1,3,4-oxadiazoles were efficiently synthesized by cyclocondensation of the appropriate 3-(pyridyl)acrylohydrazides with triethyl orthoesters in the presence of glacial acetic acid.
Agnieszka Kudelko, Karolina Jasiak, Krzysztof Ejsmont   +2 more
core   +1 more source

Design, Synthesis and Antitubercular Activity of Certain Nicotinic Acid Hydrazides

Molecules, 2015
Three series of 6-aryl-2-methylnicotinohydrazides 4a–i, N′-arylidene-6-(4-bromophenyl)-2-methylnicotino hydrazides 7a–f, and N′-(un/substituted 2-oxoindolin-3-ylidene)-6-(4-fluorophenyl)-2-methylnicotinohydrazides 8a–c were synthesized and evaluated for ...
Wagdy M. Eldehna, Mohamed Fares, Marwa M. Abdel-Aziz, Hatem A. Abdel-Aziz   +3 more
doaj   +1 more source

Extraction and separation of molybdenum(VI) from acidic media by fatty hydrazides [PDF]

, 2008
BACKGROUND: The increasing demand for molybdenum has encouraged the development of low-cost and environmentally friendly extractants to recycle and recover this metal.
Basualto, Coca, Guedes De Carvalho, Hacking, Iatsenko Gerhardt, Kyuchoukow, Lokhande, Marchese, Narita, Saberyan, Saily, Sastre, Sato, Sato, Shukla, Szczepañska, Valenzuela, Yadav, Zhao   +18 more
core   +1 more source

Synthesis, physical-chemical properties of 2-((4-R-5-(thiophene-2-ylmethyl)-4H-1,2,4-triazole-3-yl)thio)acetohydrazides

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
Aim. Analysis of the scientific literature over the past decade has shown that large synthetic possibilities towards creating new and effective drug substances have heterocyclic compounds, in particular the derivatives of 1,2,4-triazole.
O. A. Suhak, O. I. Panasenko, Ye. G. Knysh   +2 more
doaj   +1 more source