Results 21 to 30 of about 2,940 (175)
Hydrazides in the reaction with hydroxypyrrolines: less nucleophilicity – more diversity
Beilstein Journal of Organic Chemistry, 2021 Expedient protocols for the synthesis of three types of highly functionalized azaheterocyclic scaffolds (dihydropyridazines, tetrahydropyridazines, and partially saturated tricyclic systems) from readily available hydroxypyrrolines and hydrazides are ...
Dmitrii A. Shabalin +4 more
doaj +1 more source
SynOpen, 2023 A simple, eco-friendly and straightforward synthesis of hydrazones has been devised that is conducted in the presence of chitosan Hydrochloride (chitosan·HCl) as catalyst in aqueous-ethanol medium at room temperature.
Suraj N. Mali, Anima Pandey, Bapu Thorat
doaj +1 more source
Angewandte Chemie, EarlyView.A large variety of chemistry‐based ubiquitin probes have been developed. ABSTRACT Ubiquitin (Ub) and ubiquitin‐like proteins (Ubls) orchestrate diverse cellular processes through reversible post‐translational modification of target proteins. Their conjugation is governed by a cascade of E1 activating, E2 conjugating, and E3 ligating enzymes, while ...
Saibal Chanda, Wenshe Ray Liu
wiley +2 more sources
Arylhydrazines: Convenient Homogeneous Reductants for Scalable Cross‐Coupling
Angewandte Chemie, EarlyView.Reductive cross‐couplings enable efficient C–C bond formation but are limited by the heterogeneity of Zn or costly reagents like TDAE. We report arylhydrazines as inexpensive, convenient reductants for Ni‐catalyzed sp2–sp3 coupling of aryl halides and secondary alkyl iodides. Mechanistic studies support hydrazine‐mediated NiII reduction for a NiI/NiIII
Nils Kurig +5 more
wiley +2 more sources
Results in Chemistry, 2021 Three 1,2,4-triazole derivatives have been synthesised from hydrazides and 2-(2-hydroxyphenyl)-4H-1,3-benzoaxin-4-one. With the aid of Conceptual Density Functional Theory (CDFT), Molecular Electrostatic Potential (MEP) and Quantum Theory of Atoms in ...
Louis-Charl C. Coetzee +4 more
doaj +1 more source
Novel one-pot process for the synthesis of ethyl 2-imino-4-methyl-2,3-dihydrothiazole-5-carboxylates [PDF]
Journal of the Serbian Chemical Society, 2015 A facile one-pot two-step process for the synthesis of ethyl 2-imino-4-methyl-2,3-dihydrothiazole-5-carboxylates via the cyclocondensation of ethyl 2-thiocyanatoacetoacetate with a variety of hydrazine and hydrazide derivatives has been ...
Beyzaei Hamid, Aryan Reza, Moghadas Hadi
doaj +1 more source
Organic solvent-free synthesis of sulfonyl hydrazides in water
Tetrahedron Green Chem, 2023 An organic solvent-free synthesis of sulfonyl hydrazides has been achieved in water. The reactions of equimolar amount of sulfonyl chlorides and hydrazines afforded a series of substituted sulfonyl hydrazides at 60 °C for 1 h in water as a solvent in ...
Shizuki Noda, Shinji Tanimori
doaj +1 more source
Results in Chemistry, 2022 An efficient, fast, and environmentally gentle protocol for phthaloylation of amines, hydrazines and hydrazides via transamidation is described. The current research focuses on the phthaloylation of alicyclic, aliphatic, aromatic, heterocyclic amines ...
Prerna Ganwir +2 more
doaj +1 more source
Synthesis and Antioxidant Activity of Some New Coumarinyl-1,3-Thiazolidine-4-ones
Molecules, 2010 A series of Schiff’s bases (E)-N-2-aryliden-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)acetohydrazides 2a-l and N-(2-(substituted phenyl)-4-oxo-thiazolidin-3-yl)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)acetamides 3a-l were synthesized and evaluated for their ...
Valentina Rajković +4 more
doaj +1 more source
Advancing the Landscape of RNAi Nanotherapeutics for Ischemic Heart Disease
Advanced Materials, EarlyView.RNA interference (RNAi) nanomedicine revolutionizes treatment regimens for ischemic heart diseases by enabling tailored, sequence‐anchored gene regulation. This review highlights the recent advances in nanotechnology‐driven RNAi therapeutics for myocardial ischemia and discusses the key design principles that govern efficient delivery, providing ...
Han Gao, Da Pan, Hélder A. Santos
wiley +1 more source