Results 21 to 30 of about 34,898 (234)

Development and validation of RP-HPLC method for stability evaluation of model hydrazone, containing a pyrrole ring [PDF]

Pharmacia, 2019
RP-HPLC method with UV detection was developed and validated for determination of the chemical stability and stability in close to physiological conditions of a model pyrrole hydrazone ethyl 5-(4-bromophenyl)-1-(1-(2-(4-hydroxy-3-methoxybenzylidene ...
Diana Tzankova, Lily Peikova, Stanislava Vladimirova, Maya Georgieva   +3 more
doaj   +3 more sources

STUDY OF ANTIVIRAL ACTIVITY OF SOME HYDRAZONE PINOSTROBIN DERIVATIVES

Фармация и фармакология (Пятигорск), 2015
New derivatives on the basis of hydrazone pinostrobin molecule were synthesized. Significant antiviral activity of received samples of new hydrazone pinstrobin derivatives was identified.
G. K. Mukusheva, G. M. Baisarov, P. Z. Zhanymkhanova, A. Sh. Turysbaeva, A. P. Bogoyavlensky, V. E. Berezin, S. M. Adekenov   +6 more
doaj   +1 more source

(E)-3-Methyl-N′-(4-nitrobenzylidene)benzohydrazide methanol monosolvate

Acta Crystallographica Section E, 2012
The title hydrazone compound, C15H13N3O3·CH3OH, crystallized as a methanol solvate. The hydrazone molecule has an E configuration about the C=N bond and is almost planar, with a dihedral angle between the benzene rings of 5.3 (3)& ...
Chun-Bao Tang
doaj   +1 more source

6-Bromo-2'-(2-chlorobenzylidene)nicotinohydrazide and 6-Bromo-2'-(3-bromo-5-chloro-2-hydroxybenzylidene)nicotinohydrazide Methanol Solvate: Synthesis, Characterization, Crystal Structures and Antimicrobial Activities

Acta Chimica Slovenica, 2021
Two newly synthesized nicotinohydrazones, 6-bromo-2'-(2-chlorobenzylidene)nicotinohydrazide (1) and 6-bromo-2'-(3-bromo-5-chloro-2-hydroxybenzylidene)nicotinohydrazide methanol solvate (2), have been obtained and structurally characterized by ...
Hai-Yun Zhu
doaj   +1 more source

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

Hepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F. Simões, José Teixeira, Liana C. Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E. Castro, Paulo J. Oliveira, Carina Prip‐Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M. P. Rodrigues   +16 more
wiley   +1 more source

[N′-(5-Bromo-2-oxidobenzylidene-κO)-2-chlorobenzohydrazidato-κ2N′,O](methanol-κO)(methanolato-κO)oxidovanadium(V)

Acta Crystallographica Section E, 2011
The VV atom in the title complex, [V(C14H8BrClN2O2)(CH3O)O(CH3OH)], is six-coordinated by one phenolate O, one imine N and one enolic O atom of the hydrazone ligand, one oxide O atom, one methanol O atom and one methoxide O atom in a distorted octahedral
Fu-Ming Wang
doaj   +1 more source

Two Zinc(II) Complexes with Similar Hydrazone Ligands: Syntheses, Crystal Structures and Antibacterial Activities

Acta Chimica Slovenica, 2020
A pair of new mononuclear zinc(II) complexes with hydrazone ligands 4-methoxybenzoic acid (1-pyridin-2-ylmethylidene)hydrazide (HLa) and benzoic acid (1-pyridin-2-ylethylidene)hydrazide (HLb) were prepared. They are [Zn(La)2] (1) and [Zn(Lb)2] (2).
Ya-Li Sang, Xue-Song Lin, Wei-Dong Sun
doaj   +1 more source

New Amino Acid-Based Thiosemicarbazones and Hydrazones: Synthesis and Evaluation as Fluorimetric Chemosensors in Aqueous Mixtures

Molecules, 2023
Bearing in mind the interest in the development and application of amino acids/peptides as bioinspired systems for sensing, a series of new phenylalanine derivatives bearing thiosemicarbazone and hydrazone units at the side chain were synthesised and ...
Cátia I. C. Esteves, Maria Manuela M. Raposo, Susana P. G. Costa   +2 more
doaj   +1 more source

Preparation and Antimicrobial Activity of s-Triazine Hydrazones of 7-Hydroxy Coumarin and Their Metal Complexes

E-Journal of Chemistry, 2009
Metal complexes of 7-hydroxy coumarin hydrazone of s-triazine derivatives derived from 7-hydroxy-8-aceto-N-(4',6’-dichloro-1',3',5'-s-triazine) coumarin hydrazone and transition metals have been synthesized and screened for their antibacterial ...
G. R. Jani, K. B. Vyas, Zudas Franco
doaj   +1 more source

Synthesis and Biological Activity Characterization of Novel 5-Oxopyrrolidine Derivatives with Promising Anticancer and Antimicrobial Activity

Pharmaceuticals, 2022
The 1-(4-acetamidophenyl)-5-oxopyrrolidine carboxylic acid was applied for synthesizing derivatives bearing azole, diazole, and hydrazone moieties in the molecule.
Karolina Kairytė, Birutė Grybaitė, Rita Vaickelionienė, Birutė Sapijanskaitė-Banevič, Povilas Kavaliauskas, Vytautas Mickevičius   +5 more
doaj   +1 more source