Results 41 to 50 of about 59,471 (323)
Molecular Networks in Dynamic Multilevel Systems [PDF]
, 2018 Dynamic multilevel systems can be assembled from molecular building blocks through two or more reversible reactions that form covalent bonds. Molecular networks of dynamic multilevel systems can exhibit different connectivities between nodes.
Cabezudo, Ignacio +4 more
core +1 more source
Fine tuning Exo2, a small molecule inhibitor of secretion and retrograde trafficking pathways in mammalian cells [PDF]
, 2010 The small molecule 4-hydroxy-3-methoxybenzaldehyde (5,6,7,8-tetrahydro[1]benzothieno[2,3- d]pyrimidin-4-yl)hydrazone (Exo2) stimulates morphological changes at the mammalian Golgi and trans-Golgi network that are virtually indistinguishable from those ...
Barr +67 more
core +1 more source
Pharmaceuticals, 2023 In the context of a continuously increasing global cancer risk, the search for new effective and affordable anticancer drugs remains a constant demand.
Georgiana Negru (Apostol) +2 more
doaj +1 more source
Synthesis, characterisation and antimicrobial activities of vic-dioxime derivatives containing heteroaromatic hydrazone groups and their metal complexes [PDF]
Maejo International Journal of Science and Technology, 2013 Three novel heteroaromatic hydrazone derivatives bearing vic-dioxime groups (L1H2: 5-methyl-2-furfural hydrazone glyoxime, L2H2: 3-acetylpyridine hydrazone glyoxime and L3H2: 4-acetylpyridine hydrazone glyoxime) and their Ni(II), Cu(II) and Co(II ...
Halil Biyik
doaj
Pharmaceutics, 2022 A series of resveratrol/hydrazone hybrids were obtained and elucidated by spectroscopic analysis. All compounds were evaluated against colorectal cancer cells (SW480 and Sw620) and nonmalignant cell lines (HaCaT and CHO-K1) to establish the selectivity ...
Wilson Castrillón-López +5 more
doaj +1 more source
Highly efficient synthesis of the tricyclic core of Taxol by cascade metathesis [PDF]
, 2014 An efficient enantioselective synthesis of the ABC tricyclic core of the anticancer drug Taxol is reported. The key step of this synthesis is a cascade metathesis reaction, which leads in one operation to the required tricycle if appropriate fine-tuning ...
Aldegunde M. J. +39 more
core +3 more sources
Discovery of Novel Thiophene/Hydrazones: In Vitro and In Silico Studies against Pancreatic Cancer
Pharmaceutics, 2023 Cancer is the disease with the highest mortality. Drug studies contribute to promising treatments; however there is an urgent need for selective drug candidates. Pancreatic cancer is difficult to treat and the cancer progresses rapidly.
Goknil Pelin Coskun +7 more
doaj +1 more source
Fatty acid nitroalkenes ameliorate glucose intolerance and pulmonary hypertension in high-fat diet-induced obesity [PDF]
, 2014 Aims Obesity is a risk factor for diabetes and cardiovascular diseases, with the incidence of these disorders becoming epidemic. Pathogenic responses to obesity have been ascribed to adipose tissue (AT) dysfunction that promotes bioactive mediator ...
Baust, Jeff +14 more
core +1 more source
MOFs and COFs in Electronics: Bridging the Gap between Intrinsic Properties and Measured Performance
Advanced Functional Materials, EarlyView.Metal‐organic frameworks (MOFs) and covalent organic frameworks (COFs) hold promise for advanced electronics. However, discrepancies in reported electrical conductivities highlight the importance of measurement methodologies. This review explores intrinsic charge transport mechanisms and extrinsic factors influencing performance, and critically ...
Jonas F. Pöhls, R. Thomas Weitz
wiley +1 more source
Molecules, 2023 The reaction between the ((E)-N′-(2-hydroxy-3-methoxybenzylidene)pyrazine-2-carbohydrazide) (H2opch) ligand and the metallo-precursor [Dy(hfac)3]·2H2O led to the formation of an homometallic coordination complex with the formula [Dy2(hfac)3(H2O)(Hopch)2][
Bertrand Lefeuvre +4 more
doaj +1 more source