Results 61 to 70 of about 34,898 (234)
Pharmaceutics, 2022 A series of resveratrol/hydrazone hybrids were obtained and elucidated by spectroscopic analysis. All compounds were evaluated against colorectal cancer cells (SW480 and Sw620) and nonmalignant cell lines (HaCaT and CHO-K1) to establish the selectivity ...
Wilson Castrillón-López +5 more
doaj +1 more source
Advanced Science, EarlyView.A universal ROR1 antibody‐engineered lipid nanoparticle (LNP) is constructed by sequential drug encapsulation and antibody conjugation. The LNP not only enables enhanced chemotherapeutic efficiency by targeting drug delivery and precise localization of deep‐seated tumors through NIR‐II fluorescence imaging, but also remodels immunosuppressive TME ...
Yeneng Dai +12 more
wiley +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2022 In the molecule of the title compound, C9H11N5O2, the oxime and hydrazide groups are situated in a cis-position in relation to the C—C bond linking the two functional groups.
Maksym O. Plutenko +4 more
doaj +1 more source
Advanced Science, EarlyView.Random ssDNA–SWCNT(single strand DNA‐single walled carbon nanotube) library is functionally screened and evolved using high‐throughput 3D prostate tumor spheroids via iterative positive and negative selection, enabling the identification of NIR‐II fluorescent ssDNA‐SWCNT nanoprobe specific for prostate cancer.
Dakyeon Lee +8 more
wiley +1 more source
Advanced Science, EarlyView.This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård +19 more
wiley +1 more source
Advanced Science, EarlyView.This study pioneers an aggregation‐induced resonance energy transfer mechanism by synergistically integrating aggregation‐induced emission (AIE), resonance energy transfer (RET), and thermally activated delayed fluorescence (TADF) within co‐reactant conjugated polymers to develop self‐enhanced ECL emitters, which achieves an ECL efficiency up to 92.6 ...
Chao Wang +6 more
wiley +1 more source
Asymmetry in Hydrophobicity Induces Electric Potential in Non‐Charged Biomolecular Condensates
Advanced Science, EarlyView.Non‐charged biomolecular condensates can encode electric potential gradient through defining asymmetry in environmental hydrophobicity. ABSTRACT The capacity of biomolecular condensates to establish and modulate electrochemical equilibria is emerging as an important functioning mechanism in cellular biochemistry.
Leshan Yang +3 more
wiley +1 more source
Advances and Challenges in Micro/Nanocarrier‐Based Dermal Drug Delivery Systems for Acne Treatment
Advanced NanoBiomed Research, EarlyView.Topical acne treatment faces challenges from skin barriers and complex causes. Micro/nanocarriers improve drug delivery by enhancing bioavailability, targeting, and duration. Combining carriers creates synergistic effects for systematic intervention.
Jintao Yang +7 more
wiley +1 more source
Molecules, 2020 In this paper, synthesis and antimicrobial studies of 31 novel coumarin-substituted pyrazole derivatives are reported. Some of these compounds have shown potent activity against methicillin-resistant Staphylococcus aureus (MRSA) with minimum inhibitory ...
Rawan Alnufaie +6 more
doaj +1 more source
Der Nicht‐Adiabatische Charakter von Substituenteneffekten in Azobenzol
Angewandte Chemie, EarlyView.Vereinheitlichung Nicht‐Adiabatischen Schaltens: die thermische Z→E Isomerisierung von para‐substitutierten Azobenzolen verläuft über einen einzelnen Reaktionsweg mit nicht‐adiabatischem Charakter. Anstatt eines mechanistischen Wechsels spiegelt der bekannte V‐förmige Hammett Graph ein Artefakt des σp Parameters, zeigt so die Grenzen von DFT auf und ...
Jacob Jan van der Wal +4 more
wiley +1 more source