Results 121 to 130 of about 10,379 (265)
The Journal of Physiology, EarlyView.Abstract figure legend We examined the interaction effect of ovarian hormones and APOE genotype on cerebrovascular and mitochondrial function. Our data revealed that APOEε3 mice that were ovariectomized exhibited impaired endothelial function and greater oxidative stress and inflammation compared to sham controls.
Mackenzie N. Kehmeier +9 more
wiley +1 more source
Oxidation of hydrazones with iodine in the presence of base
, 1970 The oxidation of 14 hydrazones with iodine in the presence of base (generally triethylamine) was investigated. The typical reaction products are mixtures of gem-diiodides and vinyl iodides obtained in total yields of 38-85%.
A Pross, S Sternhell
core +1 more source
Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods
Chirality, Volume 38, Issue 7, July 2026.Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz +1 more
wiley +1 more source
Electroreduction of Some Substituted Hydrazones on Platinum Electrode in Dimethylformamide
, 2009 The electrochemical behaviors of 4-(1-phenyl-1-methylcyclobutane-3-yl)-2-(2-hydroxybenzylidenehydrazino)thiazole (I), 4-(1-p-xylene-1-methylcyclobutane-3-yl)-2-(2- hydroxybenzylidenehydrazino)thiazole (II), 4-(1-mesytylene-1- methylcyclobutane-3-yl)-2-(2-
Yılmaz, İbrahim +4 more
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Food Frontiers, Volume 7, Issue 4, July 2026.Apple pomace pectin is explored as a sustainable and multifunctional biomaterial for gastric ulcer management. Its unique structural features confer mucoadhesive, anti‐inflammatory, antioxidant, and anti‐Helicobacter pylori activities while enabling nano/microencapsulation of therapeutic agents.
Akash Dhiman +6 more
wiley +1 more source
Exploration of the Mitsunobu Reaction with Tosyl- and Boc-Hydrazones as Nucleophilic Agents
, 2016 Tosyl- and Boc-hydrazones were found to be effective nucleophiles in the Mitsunobu reaction. Tosyl hydrazones reacted cleanly with primary and secondary alcohols when co-administered to a cooled DBAD/PPh3 or DEAD/PPh3 complex.
John M. Keith (1464895) +1 more
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Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 7, July 2026.2‐Pyrazoline‐5‐one derivative inhibits proliferation and migration and induces Bax‐mediated apoptosis in breast cancer cells. ABSTRACT The most common cancer in women worldwide is still breast cancer. Among its subtypes, luminal A and triple‐negative breast cancers present significant therapeutic challenges due to intrinsic drug resistance and absence ...
Sevgi Kocyigit Sevinc +3 more
wiley +1 more source
MoleculesHydrazones, characterized by their C=N–NH functional group, are promising candidates in medicinal chemistry due to their ability to interact with biological targets.
Hristina Zlatanova-Tenisheva +1 more
doaj +1 more source
, 2012 Представлено основні напрямки використання гідразонів в аналітичній хімії, а також вказано можливість застосування цих органічних реагентів для визначення металів. Показано, що комплекси гідразонів з іонами металів є перспективними аналітичними формами в
Чундак, С.Ю. +2 more
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Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 7, July 2026.In HepG2 cells, Aroclor 1254 induced oxidative stress, DNA damage, apoptosis, and mutagenicity; co‐treatment with curcumin restored antioxidant defenses (GSH/thiols; SOD, CAT, GPx, GR, TrxR), reduced ROS and comet/8‐OHdG readouts, and attenuated caspase activation, demonstrating curcumin's hepatoprotective and genoprotective modulation of PCB toxicity.
Pınar Erkekoğlu +3 more
wiley +1 more source