Catalytic Methods for the Transfer of Nonstabilized Carbenes. [PDF]
Arnold ES +2 more
europepmc +1 more source
Palladium-Catalyzed Tsuji-Trost-Type Vinyl Epoxide Cross-Coupling with Umpolung Hydrazones
Recognized as versatile building blocks, vinyl epoxides have been used as electrophiles to generate compounds of high synthetic value. However, selective functionalization of vinyl epoxides via carbon-carbon (C–C) bond formation has been a major ...
Chao-Jun, Li, Evan, Chen
core +1 more source
Integrated synthesis, antiproliferative potential, and <i>in silico</i> analysis of novel pyrazole-based hydrazones derived from 3-(2-(4-chlorophenyl)hydrazineylidene)-5-phenylfuran-2(3<i>H</i>)-one. [PDF]
Ramadan SK +5 more
europepmc +1 more source
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu +6 more
wiley +1 more source
Synthesis and structure-activity relationships of indole-3-butyric acid-based hydrazones: predicting their antibacterial and antioxidant potential through integrated experimental, molecular docking and DFT studies. [PDF]
Azam M +9 more
europepmc +1 more source
Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu +9 more
wiley +1 more source
eCyclopropanation - a safe and scalable electrochemical route to cyclopropanes. [PDF]
Walsh JM +4 more
europepmc +1 more source
IPEC–J2 cell line is derived from piglet jejunal cells. Four different culture media were assessed for their ability to support IPEC‐J2 differentiation into an in vitro gut barrier. PS10 media proved most successful. Once differentiated with PS10, the IPEC‐J2 barrier was sufficiently robust for treatment with digested infant food. This demonstrates the
Francesca Bietto +6 more
wiley +1 more source
A general aqueous synthetic strategy towards 1-benzylTHIQs enabled by umpolung hydrazone. [PDF]
Kaur M +4 more
europepmc +1 more source
Ultrasound‐assisted synthesis enabled the formation of ultrafine hydrazone‐based metal complexes with controlled nanostructures and enhanced stability. Density functional theory revealed optimized geometries and electronic properties. The nanosized complexes exhibited superior antimicrobial, anticancer, and antioxidant activities, supported by ...
R. A. El‐Kasaby +7 more
wiley +1 more source

