Results 11 to 20 of about 5,842 (193)

Synthesis, Characterization and Antibacterial Activity Evaluation of New Indole-Based Derivatives

Iraqi Journal of Pharmaceutical Sciences, 2020
A new series of N-acyl hydrazones (4a-g) derived from indole-3-propionic acid (IPA) were synthesized. These N-acyl hydrazones were prepared by the reaction of 3-(1H-indol-3-yl) propane hydrazide and aldehyde in the existence of glacial acetic acid as a ...
Ahmed T. Sulaiman, Susan W. Sarsam
doaj   +1 more source

ON/OFF Photostimulation of Isatin Bipyridyl Hydrazones: Photochemical and Spectral Study

Molecules, 2019
Four novel isatin hydrazones containing bipyridyl fragments were synthesized as potential ON/OFF switches. Hydrazone Z-isomers exhibit high thermal stability.
Róbert Šandrik, Pavol Tisovský, Klaudia Csicsai, Jana Donovalová, Martin Gáplovský, Róbert Sokolík, Juraj Filo, Anton Gáplovský   +7 more
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Review on Analytical and Biological Applications of Hydrazones and their Metal Complexes

E-Journal of Chemistry, 2012
Hydrazones are very important group of analytical regents for the determination of various metal ions by using various analytical techniques. Besides this use of hydrazones are also having biological activities also.
Lakshmi Narayana Suvarapu, Young Kyo Seo, Sung-Ok Baek, Varada Reddy Ammireddy   +3 more
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Synthesis of Novel Potent Biologically Active N-Benzylisatin-Aryl Hydrazones in Comparison with Lung Cancer Drug ‘Gefitinib’

Applied Sciences, 2020
Developing anticancer therapeutics with no/few side effects is a challenge for medicinal chemists. The absence of antibacterial activity of an anticancer drug removes its detrimental effect toward intestinal flora and therefore leads to reduced side ...
Huda S. Al-Salem, Hatem A. Abuelizz, Iman S. Issa, Amany Z. Mahmoud, Ali AlHoshani, Md Arifuzzaman, A. F. M. Motiur Rahman   +6 more
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RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

Hepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F. Simões, José Teixeira, Liana C. Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E. Castro, Paulo J. Oliveira, Carina Prip‐Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M. P. Rodrigues   +16 more
wiley   +1 more source

Computational Studies of Some Hydrazone Derivatives as Antibacterial Agent: DFT and Docking Methods [PDF]

Journal of Pure and Applied Chemistry Research, 2019
Quantum chemical calculations through density functional theory and docking study were carried out on a set of seven hydrazones and S. aureus cell line (4b19) so as to observe their inhibitory abilities of hydrazones.
Abel Oyebamiji, B. Benjamin Adeleke, Ajibade Adejoro, Oyedeji Folashade   +3 more
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Synthesis, Characterization, Single-Crystal X-ray Structure and Biological Activities of [(Z)-N′-(4-Methoxybenzylidene)benzohydrazide–Nickel(II)] Complex

Crystals, 2021
(Z)-N′-(4-methoxybenzylidene)benzohydrazide (HL) and its Ni(II) complex (Ni(II)-2L) were synthesized using eco-friendly protocols. The single X-ray crystal structure of Ni(II)-2L was solved.
Inas Al-Qadsy, Abdel-Basit Al-Odayni, Waseem Sharaf Saeed, Ali Alrabie, Arwa Al-Adhreai, Lena Ahmed Saleh Al-Faqeeh, Prem Lama, Abdulaziz Ali Alghamdi, Mazahar Farooqui   +8 more
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Synthesis, E/Z isomerisation and antimicrobial studies of different structured novel ketone derivatives

Journal of the Turkish Chemical Society, Section A: Chemistry, 2019
In this study five different structured mono ketones’ (k1- k5) novel derivatives as five new hydrazones (h1-h5) and five new semicarbazones (s1-s5) were synthesized.
Aysema SAYIK MEHAN, Ebru SENTURK, Emel MATARACI KARA, Ayse Serguzel YUSUFOGLU   +3 more
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Synthesis and Conformational Assignment of N-(E)-Stilbenyloxymethylenecarbonyl-Substituted Hydrazones of Acetone and o-(m- and p-) Chloro- (nitro-) benzaldehydes by Means of and NMR Spectroscopy

Journal of Spectroscopy, 2013
Eighteen new N-(E)-stilbenyloxyalkylcarbonyl-substituted hydrazones of ortho- (meta- and para-) chloro- (nitro-) benzaldehydes 1–18 and two analogous hydrazones of acetone 19-20 were prepared.
Przemysław Patorski, Elżbieta Wyrzykiewicz, Grażyna Bartkowiak   +2 more
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The features of nucleophilic substitution of the nitro group in 4-alkyl-6-nitro-1,2,4-triazolo[5,1-c][1,2,4]triazines

Chimica Techno Acta, 2017
The nucleophilic substitution of the nitro group of 4-alkyl-6-nitro-4,7-dihydro-1,2,4-triazolo[5,1-c][1,2,4]triazine-7-ones on the example of interactionwith morpholine was studied.
E. N. Ulomsky, D. N. Lyapustin, V. V. Fedotov, O. S. El'tsov, I. M. Sapozhnikova, D. N. Kozhevnikov, E. M. Mukhin   +6 more
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