Results 61 to 70 of about 10,394 (273)

Síntese de derivados N-acilidrazônicos com potencial atividade antiparasitária [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em Química.Uma série de N-{[(5-substituído)-furan-2-il]-metilideno}-piridina-2-carboidrazidas funcionalizadas na posição ...
Raitz, Ismael
core  

Harnessing the versatility of hydrazones through electrosynthetic oxidative transformations

Beilstein Journal of Organic Chemistry
Hydrazones are important structural motifs in organic synthesis, providing a useful molecular platform for the construction of valuable compounds. Electrooxidative transformations of hydrazones constitute an attractive opportunity to take advantage of ...
Aurélie Claraz
doaj   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Synthesis of novel tri-arm star shaped 1,3,5-triazine hydrazones from 2,4,6-tris(4-acetylphenoxy)-1,3,5-triazine core [PDF]

, 2012
A series of novel symmetric triazine hydrazones [N3C3(-OC6H4-p-C(CH3)=N-NH-C(O)-C6H4-p-X)3] (X = H, Br, Cl, F, OH, OCH3, CH3, NO2, NH2) were prepared in excellent yields by a three-fold condensation reaction of 2,4,6- tris(4-acetylphenoxy)-1,3,5-triazine
Patil, B.R., Badiger, D.S., Machakanur, S.S., Pathan, A.H., Gudasi, K.B., Bligh, S.W.A.   +5 more
core   +1 more source

Synthesis of N-phenyl- and N-thiazolyl-1H-indazoles by copper-catalyzed intramolecular N-arylation of ortho-chlorinated arylhydrazones

Beilstein Journal of Organic Chemistry, 2022
The broad application of 1H-indazoles has prompted the development of several approaches for the synthesis of such compounds, including metal-free, palladium-, or copper-promoted intramolecular N-arylation of in situ-generated or isolated o ...
Yara Cristina Marchioro Barbosa, Guilherme Caneppele Paveglio, Claudio Martin Pereira de Pereira, Sidnei Moura, Cristiane Storck Schwalm, Gleison Antonio Casagrande, Lucas Pizzuti   +6 more
doaj   +1 more source

Synthesis and Biological Evaluation of Thiazolyl-Ethylidene Hydrazino-Thiazole Derivatives: A Novel Heterocyclic System

Applied Sciences, 2021
The reaction of 2-(1-(2-(2-(4-methoxybenzylidene)hydrazinyl)-4-methylthiazol-5-yl)ethylidene)hydrazinecarbothioamide with a range of hydrazonoyl chlorides and α-halo-compounds yielded three new series of thiazole derivatives.
Laila A. Al-Mutabagani, Fathy M. Abdelrazek, Sobhi M. Gomha, Ali S. Hebishy, Mohamed S. Abdelfattah, Safaa M. Hassan, Abdelwahed R. Sayed, Mahmoud M. Elaasser   +7 more
doaj   +1 more source

Metal-catalyzed fluoroalkylation of hydrazones [PDF]

, 2016
La chimie du fluor suscite un intérêt croissant de la part des chimistes organiciens de par son exploitation industrielle dans les domaines pharmaceutique et agrochimique.
Prieto, Alexis
core  

Síntese e avaliação preliminar da atividade antinociceptiva de novas isoxazolil-aril-hidrazonas

Química Nova, 2011
New 2-isoxazoline aldehydes were synthesized, in good yields, from cycloadduct of the 1,3-dipolar cycloaddition reaction between endocyclic enecarbamate and carboethoxyformonitrile oxide (CEFNO). Condensation of these 2-isoxazoline aldehydes with several
Sílvio Leandro Gonçalves Bomfim Reis, Valderes Moraes de Almeida, Gleybson Correia de Almeida, Karinna Moura Boaviagem, Charles Christophe Du Barriere Mendes, Antônio Rodolfo de Faria, Alexandre José da Silva Góes, Laudelina Rodrigues Magalhães, Teresinha Gonçalves da Silva   +8 more
doaj   +1 more source

Funktionalisierung von Peptiden auf der festen Phase im späten Synthesestadium

Angewandte Chemie, EarlyView.
Peptidmodifikationen sind für die Kontrolle der Eigenschaften von Peptidwirkstoffen von entscheidender Bedeutung. Daher sind Strategien, die einen effizienten und schnellen Einbau nicht‐kanonischer Modifikationen in Peptide in Parallelformaten ermöglichen, sehr gefragt.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source