Results 71 to 80 of about 6,255 (195)

C–H Trifluoromethylthiolation of aldehyde hydrazones

open access: yesBeilstein Journal of Organic Chemistry
The selective C–H trifluoromethylthiolation of aldehyde hydrazones afforded interesting fluorinated building blocks, which could be used as a synthetic platform.
Victor Levet   +3 more
doaj   +1 more source

Molecular Modification Strategies for CO2 Electroreduction to C2+ Products: Classifications, Mechanisms, Advances, and Perspectives

open access: yesEcoEnergy, EarlyView.
This review comprehensively outlines molecular modification strategies for steering CO2 electroreduction toward C2+ products, including the classification of diverse molecular structures, elucidation of their roles in microenvironment regulation, dissection of C–C coupling pathway engineering, and forward‐looking perspectives on machine learning and ...
Lingling Peng, Hanwen Liu, Tianyou Peng
wiley   +1 more source

The Expanding Role of Diazirines in Synthetic Methodology

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Beyond their established role in photoaffinity labeling, diazirines have emerged as versatile reagents in synthetic chemistry. This review highlights their dual reactivity as carbene and nitrogen‐transfer precursors, showcasing mechanistic insights and diverse applications in cyclopropanations, cycloadditions, skeletal editing, amination, heterocycle ...
Viktor Savic   +3 more
wiley   +1 more source

SINTEZA ŞI CARACTERISTICA HIDRAZONELOR OBŢINUTE ÎN BAZA 2-HIDRAZINOBENZOTIAZOLULUI CU PROPRIETĂŢI ANTIMICROBIENE ŞI ANTIPROLIFERATIVE

open access: yesStudia Universitatis Moldaviae: Stiinte reale si ale naturii, 2012
Nine hydrazones have been obtained on the basis of 2-hydrazinobenzothiazole. The obtained hydrazones inhibits the growth of HL-60 cells of human leukemia myeloid within the concentrations of 10-5-10-6 mol/l.
USM ADMIN
doaj  

Selective N‐Functionalization of Pyrazoles

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
This review traces the evolution of regioselective N‐functionalization strategies for pyrazoles, a key class of nitrogen heterocycles widely used in medicinal chemistry. Due to rapid tautomerism, N‐functionalization often lacks selectivity, leading to poor and unpredictable regioisomeric outcomes.
Lucas Popek   +2 more
wiley   +1 more source

One-Pot Synthesis of Novel Thiazoles as Potential Anti-Cancer Agents

open access: yesDrug Design, Development and Therapy, 2020
Abdelwahed R Sayed,1,2 Sobhi M Gomha,3,4 Eman A Taher,5,6 Zeinab A Muhammad,5 Hesham R El-Seedi,6,7 Hatem M Gaber,5 Mahgoub M Ahmed8 1Department of Chemistry, Faculty of Science, KFU, Hofuf, Saudi Arabia; 2Department of Chemistry, Faculty of Science ...
Sayed AR   +6 more
doaj  

The synthesis and characterization of some novel 5-chloro-2-(substituted alkoxy)-N-phenylbenzamide derivatives [PDF]

open access: yesJournal of the Serbian Chemical Society, 2009
To obtain biologically active compounds, the synthesis of some new derivatives with an o-hydroxybenzamide structure was performed. The ethyl esters 4–6 were obtained by the reaction of 5-chloro-2-hydroxy-N-phenylbenzamide and chloro-substituted acid ...
IOANA M. C. IENAŞCU   +4 more
doaj  

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

open access: yesExploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi   +5 more
wiley   +1 more source

Synthesis and In Vitro Antibacterial Studies of Two New Hydrazone Derivatives

open access: yesChemistry Proceedings
Throughout history to the present day, infectious diseases have been a persistent global threat, causing significant harm to public health and economic stability.
Hamza Karimatu   +5 more
doaj   +1 more source

Synthesis, Structure and Biological Activity of 2-Methyl-5-nitro-6-phenylnicotinohydrazide-Based Hydrazones

open access: yesMolecules
The synthetic availability and wide range of biological activity of hydrazides and hydrazones make them attractive subjects for investigation. In this study, we focused on synthesis of 2-methyl-5-nitro-6-phenylnicotinohydrazide-based hydrazones derived ...
Oralgazy A. Nurkenov   +10 more
doaj   +1 more source

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