Results 71 to 80 of about 2,292 (253)

Regioselective Catalytic Synthesis of Potentially Bioactive 1,3,4-Selenadiazole [PDF]

open access: yes, 2023
Isoselenocyanates have a crucial role as reactants in chemical processes, facilitating the efficient synthesis of significant chemical intermediates and physiologically active chemicals.
Mahmoud, Mohamed Ali
core   +1 more source

Synthesis of New Azoles and Azolopyrimidines Incorporating Morpholine Moiety as Potent Anti-Tumor Agents [PDF]

open access: yes, 2018
A new series of morpholinyl-chalcones 2a–d was prepared by reaction of 2-oxo-N,4-diarylbut-3-enehydrazonoyl chlorides 1a–d with morpholine. These chalcones were used as a building block for constructing pyrazoles 3a–d and 3,4-dihydropyrimidine-2(1H ...
Elham Ezz El-Arab   +3 more
core   +2 more sources

1,3,4-Thiadiazoles of pharmacological interest: Recent trends in their synthesis via tandem 1,3-dipolar cycloaddition: Review

open access: yesJournal of Advanced Research, 2014
This review article presents a survey of the utility of a new synthetic strategy for 1,3,4-thiadiazole derivatives based on reactions of nitrilimines with various functionalized sulfur dipolarophiles which proceed via tandem in situ 1,3-dipolar ...
Ahmad S. Shawali
doaj   +1 more source

Recent Applications of Sulfonium Salts in Synthesis and Catalysis

open access: yesChemistry – A European Journal, Volume 30, Issue 70, December 13, 2024.
This review summarizes the recent developments on the synthetic applications of sulfonium salts with an emphasis on the description of the operating mechanistic pathways. Abstract The use of sulfonium salts in organic synthesis has experienced a dramatic increase during the last years that can arguably be attributed to three main factors; the ...
Sven Timmann, Zeyu Feng, Manuel Alcarazo
wiley   +1 more source

Site-selectivite Synthesis and Tautomerism of Arylazo Derivatives of Pyrazolo[3,4-d]pyrimido-[1,6-b][1,2,4]triazine [PDF]

open access: yes, 2008
A simple synthetic strategy is described for synthesis of the hitherto unreported 5-arylazo-1,3-diphenyl-6-substituted-1H-pyrazolo[3,4-d]pyrimido[1,6-b][1,2,4]triazines 5a-n.
Darwish, Manal A. A.   +3 more
core  

Synthesis and Antimicrobial Activity of Some New 1,3,4-Thiadiazole Derivatives

open access: yesMolecules, 2012
New series of 1,3,4-thiadiazoles have been prepared via reaction of 1,3,4-thiadiazolenaminones 1 with N-phenyl 2-oxopropanehydrazonoyl chloride (2) in dioxane in the presence of triethylamine.
Mohamed R. Abdel Aziz   +2 more
doaj   +1 more source

Synthesis and Biological Evaluation of Some Novel Thiazole-Based Heterocycles as Potential Anticancer and Antimicrobial Agents. [PDF]

open access: yesMolecules, 2019
A novel series of thiazole-based heterocycles was synthesized using 1,3-dipolar cycloaddition reactions in the presence of chitosan-grafted-poly(vinylpyridine) as an eco-friendly biopolymeric basic catalyst.
Abu-Melha S   +5 more
europepmc   +2 more sources

Controlling (E/Z)‐Stereoselectivity of −NHC=O Chlorination: Mechanism Principles for Wide Scope Applications

open access: yesChemistry – A European Journal, Volume 30, Issue 60, October 28, 2024.
Due to the increasing interest in halo compounds in chemotherapy and protein modification/targeting in chiral bioenvironments, controlling the halogenation stereoselectivity is state‐of‐the‐art science. Halogenation of carbamoyl group (−NHC=O) has never been mechanistically studied. Herein, we dive into depths of regioselectivity and stereoselectivity,
Raed M. Maklad   +3 more
wiley   +1 more source

Sinteza i protuupalno, analgetsko i ulcerogeno djelovanje derivata tieno[2,3-d]pirimidina [PDF]

open access: yes, 2007
5-Methyl-6-phenyl-2-thioxothieno[2,3-d]pyrimidone derivative (2) reacted with hydrazonoyl chloride derivatives to afford triazolothienopyrimidones 4a-f.
A. Abdel-Fattah   +25 more
core   +2 more sources

3-Amino-8-hydroxy-4-imino-6-methyl-5-phenyl-4,5-dihydro-3H-chromeno [2,3-d ]pyrimidine: An Effecient Key Precursor for Novel Synthesis of Some Interesting Triazines and Triazepines as Potential Anti-Tumor Agents

open access: yesMolecules, 2012
A number of interesting heterocycles were prepared through interaction of the intermediate 3-amino-8-hydroxy-4-imino-6-methyl-5-phenyl-4,5-dihydro-3H-chromeno-[2,3-d]pyrimidine (1) and reagents such as hydrazonyl halides 2 to furnish triazine derivatives
Sobhi M. Gomha, Mohamed G. Badrey
doaj   +1 more source

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