Starting from N-aryl 2-aroylhydrazono-propanehydrazonoyl chlorides, a series of new functionalized 1,3,4-thiadiazoles were prepared. The structures of the compounds prepared were confirmed by both elemental and spectral analyses as well as by alternate ...
Abdou O. Abdelhamid +2 more
doaj +1 more source
AN EFFICIENT AND SIMPLE SYNTHESIS OF 2, 3-DIHYDRO-1, 3, 4-THIADIAZOLES, PYRAZOLES AND COUMARINS CONTAINING BENZOFURAN MOIETY USING BOTH CONVENTIONAL AND GRINDING METHODS [PDF]
Objective: Green chemistry is the approach for synthesizing and using of chemicals that minimize risks to human and to the environments. The aim of this study describes the synthesis of some new thiadiazole, pyrazole and coumarin derivatives bearing ...
Abdelaziem, Anhar
core +1 more source
Advances in chemical protein modification. [PDF]
Chemical protein modification has emerged as an invaluable tool for the development of modified proteins. The complementary use of both genetic and chemical methods has provided a large toolbox that allows the preparation of almost unlimited protein ...
Bernardes, Gonçalo JL, Boutureira, Omar
core +2 more sources
Advances in Mechanochemical Methods for One‐Pot Multistep Organic Synthesis
This review highlights recent advances in mechanochemical methods for multistep organic synthesis, focusing on sequential one‐pot approaches performed by grinding or ball milling. The presented transformations are discussed in terms of efficiency, applicability, and sustainability, assessing both the challenges and potential of solvent‐free one‐pot ...
Nina Biedermann, Michael Schnürch
wiley +1 more source
Recent Applications of Sulfonium Salts in Synthesis and Catalysis
This review summarizes the recent developments on the synthetic applications of sulfonium salts with an emphasis on the description of the operating mechanistic pathways. Abstract The use of sulfonium salts in organic synthesis has experienced a dramatic increase during the last years that can arguably be attributed to three main factors; the ...
Sven Timmann, Zeyu Feng, Manuel Alcarazo
wiley +1 more source
Sinteza i protuupalno, analgetsko i ulcerogeno djelovanje derivata tieno[2,3-d]pirimidina [PDF]
5-Methyl-6-phenyl-2-thioxothieno[2,3-d]pyrimidone derivative (2) reacted with hydrazonoyl chloride derivatives to afford triazolothienopyrimidones 4a-f.
A. Abdel-Fattah +25 more
core +2 more sources
Synthesis of 5-arylazothiazoles, pyridines and thieno[2,3-b]pyridines derivatives containing 1,2,3-triazole moiety [PDF]
1-(2-(4,5-dihydro-3-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-5-phenylpyrazol-1-yl)-4-subs-tituted-thiazol-5-yl)-2-phenyldiazene (4) and substituted pyridines (5-12) were synthesized via reaction of 1-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-3 ...
Abdel-Riheem, Nadia Abdelhamid +3 more
core +1 more source
2-Thioxopyrimidinyl-5-(N,N-dimethylamino)formamidine (5) and 1,3-diphenyltriazolo[3,4-d]pyrimidinyl-N,N-dimethylformamidine (14) were prepared by condensation of 6-amino-2-thioxo-1,3-dihydropyrimidin-4-one (2) and 7-amino-1,3-diphenyl-1,2,4-triazolo[4,3 ...
Tayseer A. Abdallah, Hamdi M. Hassneen
doaj +1 more source
HETEROCYCLIC SYNTHESIS USING NITRILIMINES: PART 8†. SYNTHESIS OF AROMATIC 1,2,4-TRIAZOLES [PDF]
A series of new 1,2,4-triazole derivatives (6a-p) have been synthesized by the reaction of amidines 3 with certain nitrilimines 2. The structures of newly synthesized compounds are confirmed by their analytical and spectral data including IR and NMR. Key
Abu Samahab, Ahmed S. +2 more
core
Synthesis, Antitumor Evaluation and Molecular Docking of New Morpholine Based Heterocycles
A series of new morpholinylchalcones was prepared and then used as building blocks for constructing a series of 7-morpholino-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-ones via their reaction with 6-aminothiouracil.
Zeinab A. Muhammad +5 more
doaj +1 more source

