Fungal Strains as Catalysts for the Biotransformation of Halolactones by Hydrolytic Dehalogenation with the Dimethylcyclohexane System [PDF]
Bicyclic chloro-, bromo- and iodo-γ-lactones with dimethylcyclohexane rings were used as substrates for bioconversion by several fungal strains (<em>Fusarium</em>, <em>Botrytis</em> and <em>Beauveria</em>). Most of the
Małgorzata Grabarczyk
doaj +5 more sources
Structural basis for the hydrolytic dehalogenation of the fungicide chlorothalonil. [PDF]
Cleavage of aromatic carbon-chlorine bonds is critical for the degradation of toxic industrial compounds. Here, we solved the X-ray crystal structure of chlorothalonil dehalogenase (Chd) from Pseudomonas sp. CTN-3, with 15 of its N-terminal residues truncated (ChdT), using single-wavelength anomalous dispersion refined to 1.96 Å resolution. Chd has low
Catlin DS +4 more
europepmc +5 more sources
Community-integrated multi-omics facilitates screening and isolation of the organohalide dehalogenation microorganism [PDF]
Summary: A variety of anthropogenic organohalide contaminants generated from industry are released into the environment and thus cause serious pollution that endangers human health.
Yiqun Huang +8 more
doaj +2 more sources
The Operon Encoding Hydrolytic Dehalogenation of 4-Chlorobenzoate Is Transcriptionally Regulated by the TetR-Type Repressor FcbR and Its Ligand 4-Chlorobenzoyl Coenzyme A. [PDF]
The bacterial hydrolytic dehalogenation of 4CBA is a special CoA-activation-type catabolic pathway that plays an important role in the biodegradation of polychlorinated biphenyls and some herbicides. With genetic and biochemical approaches, the present study identified the transcriptional repressor and its cognate effector of a 4CBA hydrolytic ...
Cheng M +5 more
europepmc +4 more sources
Microbial Dehalogenation of Synthetic Organohalogen Compounds: Hydrolytic Dehalogenases
Hydrolytic removal of halogen substitutents is commonly the first step in the degradation of haloaliphatic compounds by aerobic bacteria, whereas initial dehalogenation of aryl halides is rare.
Thomas Leisinger, Regula Bader
doaj +4 more sources
New Hydroxylactones and Chloro-Hydroxylactones Obtained by Biotransformation of Bicyclic Halolactones and Their Antibacterial Activity [PDF]
The aim of this study was to obtain new halolactones with a gem-dimethyl group in the cyclohexane ring (at the C-3 or C-5 carbon) and a methyl group in the lactone ring and then subject them to biotransformations using filamentous fungi.
Małgorzata Grabarczyk +6 more
doaj +2 more sources
Macroalgal microbiomes unveil a valuable genetic resource for halogen metabolism [PDF]
Background Macroalgae, especially reds (Rhodophyta Division) and browns (Phaeophyta Division), are known for producing various halogenated compounds. Yet, the reasons underlying their production and the fate of these metabolites remain largely unknown ...
Anna Lavecchia +7 more
doaj +2 more sources
Salt mine microorganisms used for the biotransformation of chlorolactones. [PDF]
The aim of the project was to find new catalysts capable of chlorolactone biotransformation. Three bicyclic chlorolactones with structures possessing one or two methyl groups in their cyclohexane ring were subjected to screening biotransformation using ...
Wanda Mączka +5 more
doaj +1 more source
Nonconventional hydrolytic dehalogenation of 1‐chlorobutane by dehydrated bacteria in a continuous solid–gas biofilter [PDF]
AbstractRhodococcus erythropolis NCIMB 13064 and Xanthobacter autotrophicus GJ10 are able to catalyze the conversion of halogenated hydrocarbons to their corresponding alcohols. These strains are attractive biocatalysts for gas phase remediation of polluted gaseous effluents because of their complementary specificity for short or medium and for mono ...
Erable, Benjamin +5 more
openaire +5 more sources
Identification of genes coding for hydrolytic dehalogenation in the metagenome derived from a denitrifying 4-chlorobenzoate degrading consortium. [PDF]
A metagenomic approach was taken to investigate the genetic basis for the ability of an anaerobic consortium to grow on either 4-chlorobenzoate or 4-bromobenzoate under denitrifying conditions. Degenerate PCR primers were designed for the family of 4-chlorobenzoyl-CoA dehalogenase genes.
Jong-Chan, Chae +2 more
openaire +2 more sources

