Results 101 to 110 of about 2,131 (236)

Acute systemic and energy metabolism responses to velocity‐based resistance training following an oral glucose load in individuals with excess body weight

open access: yesExperimental Physiology, EarlyView.
Abstract We investigated the acute metabolic effects of two velocity‐based resistance training (RT) protocols, differing in intra‐set velocity loss (VL) thresholds, on postprandial substrate oxidation and glycaemic responses following a 75 g oral glucose tolerance test in individuals with excess body weight.
Hugo Alejandro Carrillo‐Arango   +5 more
wiley   +1 more source

Beyond Glucose: A Brain Energy Bottleneck Hypothesis for Multi‐Energy Substrates in Hypoglycaemia Rescue

open access: yes
Diabetes, Obesity and Metabolism, EarlyView.
D. Russell‐Jones, M. Laffan, J. Mader
wiley   +1 more source

Acute ketone monoester ingestion lowers resting cerebral blood flow: a randomized cross‐over trial

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This double‐blind, placebo‐controlled, randomized cross‐over trial investigated the effects of ketone monoester (KME) ingestion on resting cerebral blood flow (CBF) in young adults. We demonstrate that KME supplementation lowers CBF in a dose‐dependent manner over 2‐houra post‐ingestion, whereas CBF remained unchanged following ...
Aedan J. Rourke   +7 more
wiley   +1 more source

Lactate potentiates NMDA receptor currents via an intracellular redox mechanism targeting GluN2B subunits: implications for synaptic plasticity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Astrocyte‐derived lactate enhances neuronal NMDA receptor (NMDAR) function and synaptic plasticity through a redox‐ and CaMKII‐dependent mechanism. Lactate enters neurons via monocarboxylate transporters (MCTs) and is oxidized by lactate dehydrogenase (LDH) to pyruvate, generating NADH and increasing the intracellular NADH/NAD ...
Hubert Fiumelli   +13 more
wiley   +1 more source

Inter‐Individual Differences in T1, T2, and Proton Density Using Quantitative Synthetic Imaging for 1H‐MRS Quantification

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 5, Page 2489-2499, May 2026.
ABSTRACT Purpose Metabolite concentrations can be determined from proton magnetic resonance spectroscopy (1H‐MRS) data using water as an internal reference. This calculation requires tissue‐specific water T1 and T2 relaxation constants and proton density (PD).
Samantha A. Leech   +4 more
wiley   +1 more source

Material Limitations and Processing Challenges of Bio‐Based Thermoplastics: A Review

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 14, April 10, 2026.
This review highlights recent advances in bio‐based thermoplastic polymers (b‐bTPs), focusing on their composition, formulation challenges, and industrial applications. Key aspects include the use of additives and blends to improve performance, microcellular injection molding techniques, and the recyclability of b‐bTPs foams.
Catarina Faria   +4 more
wiley   +1 more source

Effects of a Combined Dietary and Physical Activity Intervention on Bone Density, Lean Mass and Fat Mass in Adults: The GOTO Trial

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Nutritional weight‐loss interventions are known to reduce bone mineral density (BMD), which can be prevented by adding (resistance) exercise training. However, this combined effect is not well studied in non‐obese adults. In addition, the association between biomarkers and metabolite‐based composite health markers with changes in ...
F. A. Bogaards   +8 more
wiley   +1 more source

Techno‐economic analysis for hydroxy acids production from waste cellulose via alkaline digestion

open access: yesJournal of Chemical Technology &Biotechnology, Volume 101, Issue 4, Page 904-914, April 2026.
Abstract BACKGROUND Alkaline digestion offers a promising route for converting low‐grade cellulosic wastes into valuable hydroxy carboxylic acids (HAs). However, the feasibility of producing HAs at process scale, particularly the influence of reactor design on product yields, energy demand, and production costs, remains less explored.
Farangis Fallahmehneh   +3 more
wiley   +1 more source

Analyzing Nicotine Action Against Amyloid Toxicity by NMR‐Pharmacometabolomics: An Exploratory Study

open access: yesNMR in Biomedicine, Volume 39, Issue 4, April 2026.
Combined metabolomic analysis of the intracellular and extracellular portions of SH‐SY5Y cells revealed that, in the presence of Aβ 1–42, nicotine primarily influences pathways related to neurotransmission, energy metabolism, as well as the biosynthesis and degradation of membrane phospholipids.
Enza Napolitano   +5 more
wiley   +1 more source

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