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SIRT6 Mediates Sterol-Dependent Feedback Regulation of Cholesterol Biosynthetic Genes in Hepatocytes. [PDF]
Kim Y, Cho YE, Lim H, Park Y, Hwang S.
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Microsomal cytochrome P450 catalyzing the 7 alpha-hydroxylation of 27-hydroxycholesterol and dehydroepiandrosterone was partially purified from pig liver.
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Lipid remodeling in swine spermatozoa: Innovative model for the analysis of oxysterols during capacitation. [PDF]
Carlo DC +8 more
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Reconstruction of <i>de novo</i> verazine biosynthesis in <i>Saccharomyces cerevisiae</i> and computational analysis of cholesterol-binding geometry for 22<i>R</i> hydroxylation by <i>Vc</i>CYP90B27 to dissect the cyclopamine biosynthetic pathway. [PDF]
Li C +7 more
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A CRISPR activation screen identifies CH25H as a restriction factor against influenza viruses by targeting accessible cholesterol. [PDF]
Huang J +15 more
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Plasma 4β-Hydroxycholesterol Predicts Ribociclib CYP3A-Mediated Metabolism, but Not Plasma Exposure, in Patients with Primary Brain Cancer. [PDF]
Wickramasinghe C +6 more
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Candidate-gene-based study of CYP3A-related single-nucleotide polymorphisms using 4β-hydroxycholesterol/cholesterol ratio as biomarker in a Japanese cohort. [PDF]
Tanaka R +14 more
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Metabolic reprogramming of cholesterol biosynthesis drives macrophage-mediated immune suppression in HPV-negative cervical adenocarcinoma. [PDF]
Zhang J, Wei W, Zhang Y, Wang D.
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27-Hydroxycholesterol in bile duct tissue promotes cholangiocarcinoma progression through estrogen receptor signaling. [PDF]
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