Results 121 to 130 of about 16,625 (183)

Peroxisomal ABCD1 deficiency in mice drives Th1 bias through 25-HC-LXR signaling in CD4⁺ T cells. [PDF]

Front Immunol
Maeda R, Oishi M, Nagamori R, Hikosaka-Kuniishi M, Watanabe S, Lee JB, Morita M, So T.   +7 more
europepmc   +1 more source

Studies on 4b-hydroxycholesterol, a marker of CYP3A activity, and its association with 25-hydroxyvitamin D [Elektronisk resurs]

, 2015
Cholesterol is a vital compound that can undergo cytochrome P450 (CYP) mediated conversion into steroid hormones, bile acids and oxysterols. CYP enzymes are present in all human tissues and mediate the metabolism of several endogenous and exogenous ...
Nylén, H
core  

Efavirenz treatment improves retinal vaso-obliteration and pathological neovascularization in a mouse model of retinopathy of prematurity. [PDF]

Front Med (Lausanne)
Bailey B, Rudd Zhong Manis J, Seth G, Rajpurohit S, Oxenrider A, Martin PM, Jadeja RN, Thounaojam MC.   +7 more
europepmc   +1 more source

Metabolism of 25-hydroxycholesterol in mammalian cell cultures. Side-chain scission to pregnenolone in mouse L929 fibroblasts.

, 1989
Three mammalian cell lines were examined for their ability to metabolize the regulatory oxysterol, 25-hydroxycholesterol, and derepress 3-hydroxy-3-methylglutaryl CoA reductase.
Kandutsch, A A, Taylor, F R
core  

Interplay Between Gut Microbiota and Cholesterol Metabolism in Colorectal Cancer. [PDF]

Int J Mol Sci
Li SWL, Au OTH, Lau EYT, Lu RY, Zaleski AL, Liang JQ.   +5 more
europepmc   +1 more source

Immune Modulatory Oxysterols Produced from Cholesterol-Containing Lipid Nanoparticles Regulate Tumor Growth. [PDF]

ACS Nano
Back PI, Modaresahmadi S, Patel J, Subramaniyan I, Edpuganti V, Islam MR, Chowdhury S, Carr AJ, Zhang Q, Putnam WC, Li L, La-Beck NM.   +11 more
europepmc   +1 more source

The Disruption of <i>Cyp7b1</i> Controls IGFBP2 and Prediabetes Exerted Through Different Hydroxycholesterol Metabolites. [PDF]

Int J Mol Sci
Martínez-Beamonte R, Guillén N, Sánchez-Marco J, Herrera-Marcos LV, Surra JC, Navarro MA, Barranquero C, Arnal C, Puente JJ, Rodríguez-Yoldi MJ, Mendiara I, Domeño C, Nerín C, Geurts AM, Osada J, Laclaustra M.   +15 more
europepmc   +1 more source

Physiological Functions of Side-Chain-Retaining Sterols in the Brain and Their Roles in Neurodegenerative Diseases. [PDF]

Metabolites
Kiriyama Y, Nakatsuma A, Tokumaru H, Sadamoto H, Nochi H.   +4 more
europepmc   +1 more source

25-Hydroxycholesterol Restricts Japanese Encephalitis Virus via Metabolic Suppression of the SREBP2-Mediated Signaling Axis. [PDF]

Microorganisms
Liu X, Gu Y, Yang Y, Li X, Dai Y, Zhang R, Li J, Chen H, Zheng Y, Wu R.   +9 more
europepmc   +1 more source

Structure-activity relationships of steroid and sterol neuromodulators on inflammatory markers in a murine microglial cell line. [PDF]

J Steroid Biochem Mol Biol
Shu HJ, Covey DF, Zorumski CF, Mennerick S.   +3 more
europepmc   +1 more source