Results 101 to 110 of about 17,936 (215)
Isotope derivative assay of microsomal cholesterol 7 α-hydroxylase
Journal of Lipid Research, 1975 A rapid method was developed to measure cholesterol 7 α-hydroxylase activity of hepatic microsomes by the direct determination of the mass of 7 α-hydroxycholesterol formed.
S. Shefer, G. Nicolau, E.H. Mosbach
doaj +1 more source
25-Hydroxycholesterol-induced elevation in 45Ca uptake: correlation with depressed DNA synthesis.
, 1984 The mechanism whereby 25-hydroxycholesterol, an inhibitor of the synthesis of cholesterol, depresses DNA synthesis in cycling P815 mastocytoma cells was investigated. The uptake of 45Ca into P815 cells treated with 1 microgram/ml 25-hydroxycholesterol
Heiniger, H J, Boissonneault, G A
core +1 more source
Oxygenation of desmosterol and cholesterol in cell cultures.
Journal of Lipid Research, 1990 In order to determine whether hydration of the delta 24 bond of desmosterol contributes to the formation of the regulatory oxysterol, 25-hydroxycholesterol, [3H]desmosterol was incubated with two cultured cell lines and the labeled products were analyzed.
SE Saucier +4 more
doaj +1 more source
25-Hydroxycholesterol-induced elevations in 45Ca uptake: permeability changes in P815 cells.
, 1985 Certain oxysterols are capable of suppressing the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase. We have previously demonstrated that treatment of P815 cells with 1 microgram 25-hydroxycholesterol/ml culture results in a rapid ...
Heiniger, H J, Boissonneault, G A
core +1 more source
24-Hydroxycholesterol is a substrate for hepatic cholesterol 7 alpha-hydroxylase (CYP7A)
, 2000 (24S)-Hydroxycholesterol is formed from cholesterol in the brain and is important for cholesterol homeostasis in this organ. Elimination of (24S)-hydroxycholesterol has been suggested to occur in the liver but little is known about the metabolism of this
Toll, Anders, +3 more
core
, 2020 The acyltransferase LCAT mediates FA esterification of plasma cholesterol. In vitro studies have shown that LCAT also FA-esterifies several oxysterols, but in vivo evidence is lacking. Here, we measured both free and FA-esterified forms of sterols in 206
Kuroda, Masayuki +12 more
core +1 more source
The role of 27-hydroxycholesterol in meta-inflammation
The Korean Journal of Physiology & Pharmacology27-Hydroxycholesterol (27OHChol), a prominent cholesterol metabolite present in the bloodstream and peripheral tissues, is a kind of immune oxysterol that elicits immune response. Recent research indicates the involvement of 27OHChol in metabolic inflammation (meta-inflammation) characterized by chronic responses associated with metabolic ...
Son, Yonghae +3 more
openaire +2 more sources
The Configuration of 22-Hydroxycholesterol
Chemical and Pharmaceutical Bulletin, 1968 MORI, HIROMU +4 more
openaire +3 more sources
, 2015 Cholesterol is a vital compound that can undergo cytochrome P450 (CYP) mediated conversion into steroid hormones, bile acids and oxysterols. CYP enzymes are present in all human tissues and mediate the metabolism of several endogenous and exogenous ...
Hanna Nylén (18685588)
core +1 more source
, 2004 A new experimental protocol has been established for the Clemmensen reduction of diosgenin and kryptogenin with the aim to prepare deuterated isotopomers of (25R)-26-hydroxycholesterol.
E. Santaniello +3 more
core +1 more source