Results 81 to 90 of about 16,625 (183)

Serum 27-hydroxycholesterol in patients with primary biliary cirrhosis suggests alteration of cholesterol catabolism to bile acids via the acidic pathway

Journal of Lipid Research, 1998
Reduced cholesterol synthesis has been reported in patients with primary biliary cirrhosis but no data are available on changes in cholesterol catabolism induced by the disease.
M. Del Puppo, M. Galli Kienle, M.L. Petroni, A. Crosignani, M. Podda   +4 more
doaj   +1 more source

Unravelling the biochemical aspects of the interaction between ticks and Leishmania using a tick cell line

Medical and Veterinary Entomology, Volume 40, Issue 2, Page 350-359, June 2026.
Leishmania infantum propagated in IDE8 tick cell line in vitro. L. infantum reduces tick cell viability and induces reactive oxygen species production. Lipidic profile of IDE8 tick cell line is altered during Leishmania infection. Abstract Leishmaniasis comprises a group of vector‐borne neglected tropical diseases caused by species of the obligatory ...
Beatriz Filgueiras Silvestre, Karoline dos Anjos Lima, Fernanda de Paula Pepino, Daniela Cosentino‐Gomes, Adivaldo Fonseca, Lesley Bell‐Sakyi, Georgia Correa Atella, Lucia H. Pinto‐da‐Silva   +7 more
wiley   +1 more source

CYP3A induction and inhibition by different antiretroviral regimens reflected by changes in plasma 4 beta-hydroxycholesterol levels

, 2008
Objective and methods A member of the major human cytochrome P450 superfamily of hemoproteins, CYP3A4/5, converts cholesterol into 4 beta-hydroxycholesterol.
Bottiger, Y, Flamholc, L., Bertilsson, L., Ormaasen, V, Diczfalusy, U., Ormaasen, V., Bottiger, Y., Gisslén, Magnus,, Josephson, F, Bertilsson, L, Gisslen, M, Flamholc, Leo, Diczfalusy, U, Sonnerborg, A, Josephson, F., Sönnerborg, A.   +15 more
core   +1 more source

Movement of 25-hydroxycholesterol from the plasma membrane to the rough endoplasmic reticulum in cultured hepatoma cells.

Journal of Lipid Research, 1995
Oxysterols serve as both substrates and signal molecules in the cholesterol-utilizing pathways of mammalian cells. Their distribution and movement within these cells, however, have not been well characterized; therefore we have undertaken such an ...
Y Lange, J Ye, F Strebel
doaj   +1 more source

24S-hydroxycholesterol in relation to disease manifestations of acute experimental autoimmune encephalomyelitis

, 2007
Levels of the brain-specific cholesterol metabolite 24S-hydroxycholesterol are proposed as possible biomarkers for multiple sclerosis (MS). It is not yet clear for which aspect of the MS disease manifestations 24S-hydroxycholesterol is a reflection.
Dijkstra, C D, Sonke, M, Floris, S, De Vries, H E, Lütjohann, D, Teunissen, C E   +5 more
core   +1 more source

The Oxysterol 25-Hydroxycholesterol Inhibits Replication of Murine Norovirus [PDF]

, 2019
Cholesterol, an essential component of mammalian cells, is also an important factor in the replicative-cycles of several human and animal viruses.
Shawli, GT, Morgan R. Herod, Ghada T. Shawli, Morgan R. Herod, Nicola J. Stonehouse, Herod, MR, Nicola J. Stonehouse, Stonehouse, NJ, Oluwapelumi O. Adeyemi, Ghada T. Shawli, Adeyemi, OO, Oluwapelumi O. Adeyemi   +11 more
core   +1 more source

Are side-chain oxidized oxysterols regulators also in vivo?

Journal of Lipid Research, 2009
Oxsterols are oxygenated metabolites of cholesterol that are short-lived intermediates or end products in cholesterol excretion pathways. They are present in very low concentrations in mammalian systems, always accompanied by a high excess of cholesterol.
Ingemar Bjo¨rkhem
doaj   +1 more source

Cerebrotendinous xanthomatosis: reduced serum 26-hydroxycholesterol.

Journal of Lipid Research, 1982
Serum 26-hydroxycholesterol was quantitated by isotope dilution-mass spectrometry in normal individuals and in patients with cerebrotendinous xanthomatosis. In the normal individuals, the concentration of 26-hydroxycholesterol in serum ranged from 4.3 to
N B Javitt, E Kok, B Cohen, S Burstein
doaj   +1 more source

Esterification of 4β-hydroxycholesterol and other oxysterols in human plasma occurs independently of LCAT

, 2020
The acyltransferase LCAT mediates FA esterification of plasma cholesterol. In vitro studies have shown that LCAT also FA-esterifies several oxysterols, but in vivo evidence is lacking. Here, we measured both free and FA-esterified forms of sterols in 206
Kuroda, Masayuki, Holleboom, Adriaan G., Takei, Shoko, Okada, Kenta, Osuga, Jun-Ichi, Yamamuro, Daisuke, Yamazaki, Hisataka, Nagashima, Shuichi, Wakabayashi, Tetsuji, Takei, Akihito, Bujo, Hideaki, Ishibashi, Shun, Takahashi, Manabu   +12 more
core   +1 more source

Isotope derivative assay of microsomal cholesterol 7 α-hydroxylase

Journal of Lipid Research, 1975
A rapid method was developed to measure cholesterol 7 α-hydroxylase activity of hepatic microsomes by the direct determination of the mass of 7 α-hydroxycholesterol formed.
S. Shefer, G. Nicolau, E.H. Mosbach
doaj   +1 more source