Results 111 to 120 of about 16,625 (183)

Studies on 4b-hydroxycholesterol, a marker of CYP3A activity, and its association with 25-hydroxyvitamin D

, 2015
Cholesterol is a vital compound that can undergo cytochrome P450 (CYP) mediated conversion into steroid hormones, bile acids and oxysterols. CYP enzymes are present in all human tissues and mediate the metabolism of several endogenous and exogenous ...
Hanna Nylén (18685588)
core  

Antiproliferative effect of LXR agonists T0901317 and 22(R)-Hydroxycholesterol on multiple human cancer cell lines

, 2010
[[abstract]]Previously, we and other groups reported that liver X receptor (LXR) agonists T0901317, 22(R)-hydroxycholesterol, and 24(S) -hydroxycholesterol suppressed the proliferation of prostate and breast cancer cells.
Chuu, CP;Lin, HP
core  

Sterol synthesis in variant Chinese hamster lung cells selected for resistance to 25-hydroxycholesterol. Cross-resistance to 7-ketocholesterol, 20alpha-hydroxycholesterol, and serum.

, 1979
Two lines of Chinese hamster lung (Dede) cells which are resistant to the killing effect of 25-hydroxycholesterol, and which grow to confluence in its presence, have been isolated.
Kandutsch, A A, Chen, H W, Cavenee, W K
core  

Development of determination methods of 7α-hydroxycholesterol in excess of cholesterol on boron doped diamond electrode

This bachelor's thesis was aimed at development of a method of determination of 7α-hydroxycholesterol in a mixture containing cholesterol in excess on boron doped diamond electrode. The substances were studied separately at first.
Šťovíková, Tereza
core   +1 more source

Effects of 25-hydroxycholesterol and 7-ketocholesterol, inhibitors of sterol synthesis, administered orally to mice.

, 1977
When 25-hydroxycholesterol or 7-ketocholesterol was fed to mice with the diet, growth was suppressed and mature mice lost weight. The effect of the 7-ketone upon body weight was effectively counteracted by cholesterol whereas cholestanol and beta ...
Kandutsch, A A, Heiniger, H J, Chen, H W, Heiniger, H   +3 more
core  

A CRISPR activation screen identifies CH25H as a restriction factor against influenza viruses by targeting accessible cholesterol. [PDF]

Emerg Microbes Infect
Huang J, Ma K, Ding S, Wang Y, Xiong J, Yi J, Zhang J, He Z, Huang L, Ren X, Zhou J, Chen X, Liu L, Qi W, Wang S, Liao M.   +15 more
europepmc   +1 more source

Metabolic reprogramming of cholesterol biosynthesis drives macrophage-mediated immune suppression in HPV-negative cervical adenocarcinoma. [PDF]

Front Immunol
Zhang J, Wei W, Zhang Y, Wang D.
europepmc   +1 more source

27-Hydroxycholesterol in bile duct tissue promotes cholangiocarcinoma progression through estrogen receptor signaling. [PDF]

Am J Cancer Res
Konishi N, Miyazaki T, Shimoda M, Morishita Y, Honda A, Ikegami T, Suzuki S.   +6 more
europepmc   +1 more source

Hypertension in Overweight and Obesity: Sex-Specific Role of 4β-Hydroxycholesterol. [PDF]

J Am Heart Assoc
Rahunen R, Merikallio H, Rinne V, Savolainen MJ, Hukkanen J.   +4 more
europepmc   +1 more source

A novel sex-specific role for 27-hydroxycholesterol in early-onset schizophrenia. [PDF]

Ann Gen Psychiatry
Sun Z, Liu M, Yan J, Wu Y, Wang H, Li Y, Tang Y, Zheng Y, Li R.   +8 more
europepmc   +1 more source