Results 161 to 170 of about 16,625 (183)

Lipid metabolism reprogramming shapes the immune landscape in the tumor microenvironment. [PDF]

Cell Mol Immunol
Du YW, Cai ZR, Duan XT, Li XY, Yue T, Tian T, Li JJ, Ju HQ.   +7 more
europepmc   +1 more source

Drug Interaction PBPK Modeling: Review of the Literature Exposes the Need for Increased Verification of Model Inputs and Outputs as Part of Credibility Assessment. [PDF]

Clin Transl Sci
Rodrigues D, Gibson CR, Isoherranen N.
europepmc   +1 more source

25-Hydroxycholesterol Effect on Membrane Structure and Mechanical Properties [PDF]

International Journal of Molecular Sciences, 2021
Cholesterol is responsible for the plasticity of plasma membranes and is involved in physiological and pathophysiological responses. Cholesterol homeostasis is regulated by oxysterols, such as 25-hydroxycholesterol.
Marco M Domingues, Barbara Gomes, Axel Hollmann   +2 more
exaly   +2 more sources

7β-Hydroxycholesterol induces Ca2+ oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells

Atherosclerosis, 2000
In the present study, we characterize the early cytotoxic effects of 7β-hydroxycholesterol, a major cytotoxin in oxidized LDL, in human aortic smooth muscle cells. Within a few minutes after addition, 7β-hydroxycholesterol induced Ca 2+ oscillations with
Mikko P S Ares, Johan Thyberg, Lisa Juntti-Berggren   +2 more
exaly   +2 more sources

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Attenuation of 7-ketocholesterol- and 7β-hydroxycholesterol-induced oxiapoptophagy by nutrients, synthetic molecules and oils: Potential for the prevention of age-related diseases

Ageing Research Reviews, 2021
J P Pais de Barros, M Hammami, John J Mackrill   +2 more
exaly  

The cholesterol metabolite 25-hydroxycholesterol restrains the transcriptional regulator SREBP2 and limits intestinal IgA plasma cell differentiation

Immunity, 2021
Bruno C Trindade, Simona Ceglia, Alyssa Berthelette   +2 more
exaly  

The Controversial Role of 24-S-Hydroxycholesterol in Alzheimer’s Disease

Antioxidants, 2021
Paola Gamba, Serena Giannelli, Erica Staurenghi   +2 more
exaly