Results 71 to 80 of about 5,125,991 (297)
This paper reviews the state of the art and recent developments in thin‐film biosensors for the detection of neurotransmitters, small molecules, and biomarkers within flexible, implantable bioelectronic systems. It covers the main sensing modalities, including electrochemical, plasmonic, acoustic, and magnetic, alongside their materials, transduction ...
Massimo Mariello
wiley +1 more source
Glioma induced alterations in fecal short-chain fatty acids and neurotransmitters
Aim: To explore fecal short-chain fatty acids and neurotransmitter alterations in a mouse–glioma model and glioma patients. Methods: Liquid chromatography–mass spectrometry and 16S rRNA-sequencing from fecal samples were performed to measure metabolite ...
Antonio Dono +8 more
doaj +1 more source
Impulsive traits and 5-HT2A receptor promoter polymorphism in alcohol dependents: Possible association but no influence of personality disorders [PDF]
Objective: Impulsive behavior in alcoholics puts them at serious risk of severer course of disease and has been related to the serotonergic neurotransmission dysfunction.
Bahlmann, Miriam +4 more
core +1 more source
CY alleviates colitis and associated neuropsychiatric symptoms by reducing serum LPS, restoring intestinal barrier integrity, and modulating serotonin metabolism. It inhibits neuroinflammation, improves synaptic function, and normalizes HPA axis hyperactivity via downregulation of HTR2C, offering a multi‐targeted strategy for gut–brain axis dysfunction
Yifan Cui +9 more
wiley +1 more source
Motor deficit is a core symptom of Rett syndrome, a rare neurological disease caused in most cases by mutations of the methyl-CpG-binding protein2 (MECP2) gene. Serotonin reuptake inhibitors improve motor coordination in Mecp2 heterozygous (Het) mice and
Claudia Villani +2 more
doaj +1 more source
An unusual case of multiple myeloma [PDF]
The case concerns the unusual presentation of a non-secretory multiple myeloma with diarrhoea secondary to large bowel infiltration. In December 2009, a 74-year-old lady presented to hospital and complained of a two year history of intermittent ...
Delicata, Julian, Farrugia, Daniel
core
Phase 3 Trial of 177Lu-Dotatate for Midgut Neuroendocrine Tumors [PDF]
Background Patients with advanced midgut neuroendocrine tumors who have had disease progression during first-line somatostatin analogue therapy have limited therapeutic options.
Al‐nahhas, A +82 more
core +1 more source
ABSTRACT Background and Aims Depression, a leading global cause of disease burden, often shows limited response and notable adverse reactions to existing antidepressants. Exploring combination therapies is therefore crucial to enhance therapeutic efficacy and improve safety.
Yanting Fan +3 more
wiley +1 more source
Somatostatin analogs in neuroendocrine tumors with Ki‐67 index of ≥10%
Abstract Somatostatin analogs (SSAs) are an established first‐line therapy in intestinal and pancreatic neuroendocrine tumors (NETs). Based on Phase III studies, their use is recommended in NET with a Ki‐67 index of up to 10%. The effect of first‐line SSA therapy on differentiated NET with a Ki‐67 index ≥10% is poorly understood.
Johanna Braegelmann +6 more
wiley +1 more source
Catecholamine and serotonin are biogenic amines (BAs) that serve as neurotransmitters and play an important role in the regulation of cardinal functions that are mainly altered during central nervous system (CNS) infections.
Aneela Taj, Nusrat Jamil
doaj +1 more source

