Results 11 to 20 of about 6,933 (234)

Effect of 8-hydroxyquinoline and derivatives on human neuroblastoma SH-SY5Y cells under high glucose [PDF]

PeerJ, 2016
8-Hydroxyquinoline and derivatives exhibit multifunctional properties, including antioxidant, antineurodegenerative, anticancer, anti-inflammatory and antidiabetic activities.
Wilasinee Suwanjang, Supaluk Prachayasittikul, Virapong Prachayasittikul   +2 more
doaj   +2 more sources

Synthesis and Antimicrobial Activity of Novel Substituted Ethyl 2-(Quinolin-4-yl)-propanoates

Molecules, 2013
Substituted 4-hydroxyquinolines were synthesized from anilines and diethyl 2-(ethoxymethylene)malonate by the Gould-Jacobs reaction via cyclization of the intermediate anilinomethylenemalonate followed by hydrolysis and decarboxylation.
Yong Zhou, Kim Drummond Rainsford, Keith Miller, M. Akram Khan   +3 more
doaj   +1 more source

Recent Advances in the Synthesis and Biological Activity of 8-Hydroxyquinolines

Molecules, 2020
Compounds containing the 8-hydroxyquinoline (8-HQ) 1 nucleus exhibit a wide range of biological activities, including antimicrobial, anticancer, and antifungal effects.
Haythem A. Saadeh, Kamal A. Sweidan, Mohammad S. Mubarak   +2 more
doaj   +1 more source

Vanadium(IV) Complexes with Methyl-Substituted 8-Hydroxyquinolines: Catalytic Potential in the Oxidation of Hydrocarbons and Alcohols with Peroxides and Biological Activity

Molecules, 2021
Methyl-substituted 8-hydroxyquinolines (Hquin) were successfully used to synthetize five-coordinated oxovanadium(IV) complexes: [VO(2,6-(Me)2-quin)2] (1), [VO(2,5-(Me)2-quin)2] (2) and [VO(2-Me-quin)2] (3).
Joanna Palion-Gazda, André Luz, Luis R. Raposo, Katarzyna Choroba, Jacek E. Nycz, Alina Bieńko, Agnieszka Lewińska, Karol Erfurt, Pedro V. Baptista, Barbara Machura, Alexandra R. Fernandes, Lidia S. Shul’pina, Nikolay S. Ikonnikov, Georgiy B. Shul’pin   +13 more
doaj   +1 more source

In-Out Surface Modification of Halloysite Nanotubes (HNTs) for Excellent Cure of Epoxy: Chemistry and Kinetics Modeling

Nanomaterials, 2021
In-out surface modification of halloysite nanotubes (HNTs) has been successfully performed by taking advantage of 8-hydroxyquinolines in the lumen of HNTs and precisely synthesized aniline oligomers (AO) of different lengths (tri- and pentamer) anchored ...
Shahab Moghari, Seyed Hassan Jafari, Mohsen Khodadadi Yazdi, Maryam Jouyandeh, Aleksander Hejna, Payam Zarrintaj, Mohammad Reza Saeb   +6 more
doaj   +1 more source

Resonance raman characterization of the forms of ground-state 8-substituted 7-hydroxyquinoline caged acetate compounds in aqueous solutions [PDF]

, 2010
Monday Poster Session: Resonance Raman in Biological and Chemical Systems (MP22) - Poster Number: 0978-substituted 7-hydroxyquinolines, like 8-chloro-7-hydroxyquinoline (CHQ) and 8-cyano-7-hydroxyquinoline (CyHQ), are able to be useful for 1PE and 2PE ...
An, H, Dore, TM, Harris, KT, Li, W, Ma, C, Phillips, DL   +5 more
core   +1 more source

Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA

mBio, 2019
A defining characteristic of treating tuberculosis is the need for prolonged administration of multiple drugs. This may be due in part to subpopulations of slowly replicating or nonreplicating Mycobacterium tuberculosis bacilli exhibiting phenotypic ...
Landys Lopez Quezada, Sandra Silve, Mark Kelinske, Amir Liba, Constantino Diaz Gonzalez, Martin Kotev, Laurent Goullieux, Stephanie Sans, Christine Roubert, Sophie Lagrange, Eric Bacqué, Cedric Couturier, Alain Pellet, Isabelle Blanc, Marlène Ferron, Fabrice Debu, Kelin Li, Jeffrey Aubé, Julia Roberts, David Little, Yan Ling, Jun Zhang, Ben Gold, Carl Nathan   +23 more
doaj   +1 more source

Clioquinol synergistically augments rescue by zinc supplementation in a mouse model of acrodermatitis enteropathica. [PDF]

PLoS ONE, 2013
BackgroundZinc deficiency due to poor nutrition or genetic mutations in zinc transporters is a global health problem and approaches to providing effective dietary zinc supplementation while avoiding potential toxic side effects are needed.Methods ...
Jim Geiser, Robert C De Lisle, David Finkelstein, Paul A Adlard, Ashley I Bush, Glen K Andrews   +5 more
doaj   +1 more source

Antimalarial and antimicrobial activities of 8-aminoquinoline-uracils metal complexes [PDF]

, 2016
8-Aminoquinoline (8AQ) derivatives have been reported to have antimalarial, anticancer, and antioxidant activities. This study investigated the potency of 8AQ-5-substituted (iodo and nitro) uracils metal (Mn, Cu, Ni) complexes (1-6) as antimalarial and ...
Kunwittaya, Sarun, Phopin, Kamonrat, Prachayasittikul, Supaluk, Prachayasittikul, Virapong, Ruchirawat, Somsak, Sinthupoom, Nujarin, Treeratanapiboon, Lertyot   +6 more
core   +1 more source

Investigating the Activity Spectrum for Ring-Substituted 8-Hydroxyquinolines

Molecules, 2010
In this study, a series of fourteen ring-substituted 8-hydroxyquinoline derivatives were prepared. The synthesis procedures are presented. The compounds were analyzed using RP-HPLC to determine lipophilicity.
Aidan Coffey, Jim O'Mahony, Marcela Vejsova, Katarina Kralova, James Carroll, Jacek E. Nycz, Matus Pesko, Josef Jampilek, Robert Musiol, Anna Mrozek, Jaroslaw Polanski   +10 more
doaj   +1 more source