Two-Metal Ion-Dependent Enzymes as Potential Antiviral Targets in Human Herpesviruses
mBio, 2022 The majority of drug discovery efforts against herpesviruses have focused on nucleoside analogs that target viral DNA polymerases, agents that are associated with dose-limiting toxicity and/or a narrow spectrum of activity.
Katherine A. DiScipio +6 more
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Tạp chí Khoa học Đại học Huế: Khoa học Tự nhiên, 2020 In this work, a theoretical study for platinum(II)-8-hydroxyquinoline-tetrylene complexes [{PtCl–C9H6NO}–NHEPh] (Pt–EPh) is carried out for the first time by using the density functional theory (DFT).
Huynh Thi Phuong Loan +2 more
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Molecules, 2021 Despite the common use of salens and hydroxyquinolines as therapeutic and bioactive agents, their metal complexes are still under development. Here, we report the synthesis of novel mixed-ligand metal complexes (MSQ) comprising salen (S), derived from (2,
Badriah Saad Al-Farhan +7 more
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Validated stability indicating liquid chromatographic determination of ebastine in pharmaceuticals after pre column derivatization: Application to tablets and content uniformity testing [PDF]
, 2011 An accurate, simple, sensitive and selective reversed phase liquid chromatographic method has been developed for the determination of ebastine in its pharmaceutical preparations. The proposed method depends on the complexation ability of the studied drug
Fawzia Ibrahim +3 more
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High-throughput screening with the Eimeria tenella CDC2-related kinase2/cyclin complex EtCRK2/EtCYC3a [PDF]
, 2012 The poultry disease coccidiosis, caused by infection with Eimeria spp. apicomplexan parasites, is responsible for enormous economic losses to the global poultry industry.
Aziz +12 more
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, 2014 Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust +15 more
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Synthesis and biological characterization of organoruthenium complexes with 8-hydroxyquinolines [PDF]
, 2018 In this study we report the synthesis, characterization and a thorough biological evaluation of twelve organoruthenium–8-hydroxyquinolinato (Ru-hq) complexes. The chosen hqH ligands bear various halogen atoms in different positions which enables to study
Bai, Yang +7 more
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In vitro selective growth-inhibitory effect of 8-hydroxyquinoline on Clostridium perfringens versus Bifidobacteria in a medium containing chicken ileal digesta [PDF]
, 2016 Clostridium perfringens-induced necrotic enteritis is generally controlled by antibiotics. However, because of increasing antibiotic resistance, other antibacterial agents are required, preferably ones that do not affect the beneficial intestinal ...
Hovorkova, Petra +3 more
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Synthesis of 4-Alkoxy-8-hydroxyquinolines [PDF]
The Journal of Organic Chemistry, 2007 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Juha P, Heiskanen +5 more
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Syntheses, transformations and applications of aminonaphthol derivatives prepared via modified Mannich reactions [PDF]
, 2013 A special alteration is the three-component modi fi ed Mannich reaction (mMR), in which formaldehyde is replaced by an aromatic aldehyde, the secondary amine by ammonia, and the C e H acid by an electron-rich aromatic compound such as 1- or 2 ...
Fülöp, Ferenc, Szatmári, István
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