Preparation of 8-hydroxyquinoline wires by decomposition of tris(8-hydroxyquinoline) aluminium [PDF]
Journal of Experimental Nanoscience, 2012 We fabricated 8-hydroxyquinoline (HQ) wires by two methods, decomposition of tris(HQ) aluminium at low pressure in a tube furnace and heating of HQ powder at atmospheric pressure. Fabricated wires were crystalline, and exhibited the same optical properties (absorption and photoluminescence) as HQ powder.
Chan, WK +4 more
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Anti-trypanosomal 8-hydroxyl naphthyridines are chelators of divalent transition metals [PDF]
, 2018 The lack of information regarding the mechanisms of action (MoA) or specific molecular targets of phenotypically active compounds can prove a barrier to their development as chemotherapeutic agents.
Fairlamb, Alan +10 more
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PLoS ONE, 2010 BackgroundSmall molecule modulators of epigenetic processes are currently sought as basic probes for biochemical mechanisms, and as starting points for development of therapeutic agents.
Oliver N F King +16 more
doaj +1 more source
Novel highly emissive non proteinogenic amino acids : synthesis of 1,3,4-thiadiazolyl asparagines and evaluation as fluorimetric chemosensors for biologically relevant transition metal cations [PDF]
, 2011 Highly emissive heterocyclic asparagine derivatives bearing a 1,3,4-thiadiazolyl unit at the side chain, functionalised with electron donor or acceptor groups, were synthesised and evaluated as amino acid based fluorimetric chemosensors for metal cations
A García-Raso +44 more
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International Journal of Polymer Science, 2018 The structure modification of chitosan has great application potential. 6-Oxychitosan was prepared by specially oxidizing the C6-OH of chitosan, then 6-oxychitosan was reacted with three kinds of aldehydes to prepare N-quaternized 6-oxychitosan ...
Kun Gao +7 more
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Di-san junyi daxue xuebao, 2019 Objective To discover novel indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitors with new scaffold structures by screening ZINC and Chembridge databases using pharmacophore modeling and molecular docking.
ZHANG Yuping, SHAN Changyu, GUO Haiqiong
doaj +1 more source
Navigating the Chemical Space of Multitarget-Directed Ligands:From Hybrids to Fragments in Alzheimer's Disease [PDF]
, 2016 Multitarget drug discovery is one of the hottest topics and most active fields in the search for new molecules against Alzheimer’s disease (AD). Over the last 20 years, many promising multitarget-directed ligands (MTDLs) have been identified and ...
Andrea Cavalli +3 more
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The synthesis of Waltherione F and analogues with modifications at the 2- and 3-positions as potential antitrypanosomal agents [PDF]
, 2019 Chagas disease also know as American Trypanosomiasis (AT) is a tropical parasitic disease endemic in South America, is caused by Trypanosoma cruzi which is transmitted by the blood‐sucking insect vectors called triatomine bugs.
Arroyo Aguilar +20 more
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The Crystal Structures of Metal 8-Hydroxyquinolinate. I. Copper 8-Hydroxyquinolinate [PDF]
Bulletin of the Chemical Society of Japan, 1963 Abstract The crystal structure of anhydrous copper 8-hydroxyquinolinate has been determined by the two-dimensional Fourier method. It is monoclinic and has been shown to belong to the B21/a space group, with eight molecules in a cell of the dimensions: a=23.66, b=8.72, c=15.30Å and β=117.5.
Fumikazu Kanamaru +2 more
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Epigenomic Regulation of Androgen Receptor Signaling: Potential Role in Prostate Cancer Therapy. [PDF]
, 2017 Androgen receptor (AR) signaling remains the major oncogenic pathway in prostate cancer (PCa). Androgen-deprivation therapy (ADT) is the principle treatment for locally advanced and metastatic disease.
Cucchiara, Vito +5 more
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