In vitro selective growth-inhibitory effect of 8-hydroxyquinoline on Clostridium perfringens versus Bifidobacteria in a medium containing chicken ileal digesta [PDF]
Clostridium perfringens-induced necrotic enteritis is generally controlled by antibiotics. However, because of increasing antibiotic resistance, other antibacterial agents are required, preferably ones that do not affect the beneficial intestinal ...
Hovorkova, Petra +3 more
core +3 more sources
Preparation of 8-hydroxyquinoline wires by decomposition of tris(8-hydroxyquinoline) aluminium [PDF]
We fabricated 8-hydroxyquinoline (HQ) wires by two methods, decomposition of tris(HQ) aluminium at low pressure in a tube furnace and heating of HQ powder at atmospheric pressure. Fabricated wires were crystalline, and exhibited the same optical properties (absorption and photoluminescence) as HQ powder.
Chan, WK +4 more
openaire +3 more sources
Novel highly emissive non proteinogenic amino acids : synthesis of 1,3,4-thiadiazolyl asparagines and evaluation as fluorimetric chemosensors for biologically relevant transition metal cations [PDF]
Highly emissive heterocyclic asparagine derivatives bearing a 1,3,4-thiadiazolyl unit at the side chain, functionalised with electron donor or acceptor groups, were synthesised and evaluated as amino acid based fluorimetric chemosensors for metal cations
A García-Raso +44 more
core +1 more source
BackgroundSmall molecule modulators of epigenetic processes are currently sought as basic probes for biochemical mechanisms, and as starting points for development of therapeutic agents.
Oliver N F King +16 more
doaj +1 more source
Navigating the Chemical Space of Multitarget-Directed Ligands:From Hybrids to Fragments in Alzheimer's Disease [PDF]
Multitarget drug discovery is one of the hottest topics and most active fields in the search for new molecules against Alzheimer’s disease (AD). Over the last 20 years, many promising multitarget-directed ligands (MTDLs) have been identified and ...
Andrea Cavalli +3 more
core +3 more sources
The structure modification of chitosan has great application potential. 6-Oxychitosan was prepared by specially oxidizing the C6-OH of chitosan, then 6-oxychitosan was reacted with three kinds of aldehydes to prepare N-quaternized 6-oxychitosan ...
Kun Gao +7 more
doaj +1 more source
Objective To discover novel indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitors with new scaffold structures by screening ZINC and Chembridge databases using pharmacophore modeling and molecular docking.
ZHANG Yuping, SHAN Changyu, GUO Haiqiong
doaj +1 more source
The synthesis of Waltherione F and analogues with modifications at the 2- and 3-positions as potential antitrypanosomal agents [PDF]
Chagas disease also know as American Trypanosomiasis (AT) is a tropical parasitic disease endemic in South America, is caused by Trypanosoma cruzi which is transmitted by the blood‐sucking insect vectors called triatomine bugs.
Arroyo Aguilar +20 more
core +1 more source
Organocatalytic Enantioselective Functionalization of Hydroxyquinolines through an aza-Friedel-Crafts Alkylation with Isatin-derived Ketimines [PDF]
A highly enantioselective addition o hydroxyquinolines to isatin-derived ketimines hasbeen realized using a quinine-derived thiourea organocatalyst. The reaction affords chiral 3-amino-2-oxindoles bearing a quinoline moiety with a quaternary stereocenter
Aleman +63 more
core +2 more sources
The Crystal Structures of Metal 8-Hydroxyquinolinate. I. Copper 8-Hydroxyquinolinate [PDF]
Abstract The crystal structure of anhydrous copper 8-hydroxyquinolinate has been determined by the two-dimensional Fourier method. It is monoclinic and has been shown to belong to the B21/a space group, with eight molecules in a cell of the dimensions: a=23.66, b=8.72, c=15.30Å and β=117.5.
Fumikazu Kanamaru +2 more
openaire +1 more source

