Results 41 to 50 of about 1,976 (187)

Impact of copper and iron binding properties on the anticancer activity of 8-hydroxyquinoline derived Mannich bases. [PDF]

, 2018
The anticancer activity of 8-hydroxyquinolines relies on complex formation with redox active copper and iron ions. Here we employ UV-visible spectrophotometry and EPR spectroscopy to compare proton dissociation and complex formation processes of the ...
Enyedy, Éva A., Fülöp, Ferenc, Gál, G. Tamás, May, Nóra V., Pape, Veronika F.S., Szakács, Gergely, Szatmári, István, Szeri, Flóra   +7 more
core   +1 more source

Organocatalytic Enantioselective Functionalization of Hydroxyquinolines through an aza-Friedel-Crafts Alkylation with Isatin-derived Ketimines [PDF]

, 2018
A highly enantioselective addition o hydroxyquinolines to isatin-derived ketimines hasbeen realized using a quinine-derived thiourea organocatalyst. The reaction affords chiral 3-amino-2-oxindoles bearing a quinoline moiety with a quaternary stereocenter
Aleman, Amr, Arai, Bentley, Bentley, Bernard, Berti, Black, Brandes, Chauhan, Chrzanowska, Connon, Decaux, Doyle, Eicher, Engl, Feng, Feng, Fischer, Hara, Holmquist, Holmquist, Husmann, Iwai, Jia, Kano, Kaur, Kodama, Kumari, Manske, Marcelli, Marella, Michael, Montesinos-Magraner, Montesinos-Magraner, Montesinos-Magraner, Nakamura, Nakamura, Ochi, Oost, Pappoppula, Prajapati, Rueping, Rueping, Rueping, Shields, Shimazaki, Sun, Takamura, Takemoto, Thinnes, Tian, Vila, Volla, Wang, Wu, Xu, Yamaoka, Yu, Zhang, Zhao, Zhao, Zhao, Zurro   +63 more
core   +2 more sources

Evaluation of a Product Intended for Microbiological Control in Animal Production, and Its Combination With Halquinol

Animal Research and One Health, EarlyView.
Activo Liquid and Halquinol inhibit Salmonella and Escherichia coli in culture media. Activo Liquid exhibits bactericidal action, whereas HA is bacteriostatic, and their combination results in positive or indifferent interactions. This combination effectively inhibits E. coli throughout digestion simulation, thus reducing the required concentrations of
Alberto Gonçalves Evangelista, Lucas dos Santos Janotto, Adriana Paula Possamai, Carolina Cini Perry, Francine Lemes Ribeiro, Rafael Canonenco de Araujo, Fernando Bittencourt Luciano   +6 more
wiley   +1 more source

Fluorescence Analysis for Multi-Site Aluminum Binding to Natural Organic Matter [PDF]

, 1998
Natural organic matter (NOM) samples isolated from different water sources in Norway were compared using their fluorescence properties. Fluorescence surfaces were observed at pH 4.36 and deconvoluted using SIMPLISMA (Windig and Guilment 1991). There were
Kramer, James R., Smith, D. Scott
core   +1 more source

No Charging but Protection: Lifetime Prolongation of Spontaneously‐polarized Electrets for Energy Harvesting Applications

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A bilayer protection approach is proposed for slowing down the surface potential decay of thin films of spontaneously‐polarized electret materials. The electret and the protective films are characterized, and the protection effectiveness is investigated under the effects of light illumination, water contact and mechanical impact.
Seyedali Sabzpoushan, Henry Juncker, Peter Woias   +2 more
wiley   +1 more source

Synthesis and cytotoxic studies of a new series quinolinoxymethylcoumarins [PDF]

, 2013
4-Bromomethylcoumarins (1a-k) were reacted with 8-hydroxyquinolines (2a-b) to yield quinolinoxymethylcoumarins (3a-o). The structure of all the synthesized compounds were confirmed by spectral studies and screened for their anticancer activities against ...
Pandi, V., Rasal, V.P., Shamala, D., Shivashankar, K., Vivek, P.V.   +4 more
core  

Aliphatic Poly(Carbonate)s with Acid Responsive Release Mechanisms for Micellar Anti‐Tumor Drug Delivery

Macromolecular Rapid Communications, EarlyView.
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley   +1 more source

2-Alkyl-4-hydroxyquinolines from a Marine-Derived Streptomyces sp. Inhibit Hyphal Growth Induction in Candida albicans

Marine Drugs, 2019
Four 2-alkyl-4-hydroxyquinoline derivatives (1⁻4) were isolated from a semisolid rice culture of the marine-derived actinomycete Streptomyces sp. MBTG13.
Heegyu Kim, Ji-Yeon Hwang, Beomkoo Chung, Eunji Cho, Suhyun Bae, Jongheon Shin, Ki-Bong Oh   +6 more
doaj   +1 more source

Cellular analysis of the action of epigenetics drugs and probes [PDF]

, 2017
Small molecule drugs and probes are important tools in drug discovery, pharmacology, and cell biology. This is of course also true for epigenetic inhibitors.
A. Ganesan, Edwards AM, Fides Zenk, Gajer (née Wagner) J, Glaser KB, Glaser KB, Jung M, Lynch JT, Maeda T, Manfred Jung, Mirjam Hau, Nicola Iovino, van Lint C   +12 more
core   +1 more source

Synthetic Raphanobrassica Genome Reveals Functional and Evolutionary Insights Into Clubroot Resistance Genes on Chromosome R5

Plant Biotechnology Journal, EarlyView.
ABSTRACT Clubroot, a severe soil‐borne disease caused by Plasmodiophora brassicae, poses a severe threat to global production of Brassicaceae oilseed crops and vegetables. To date, there has been a serious lack of clubroot‐resistant germplasms in Brassica napus (AACC), necessitating the urgent development of novel disease‐resistant germplasm.
Xueqing Zhou, Meixiu Wu, Zhiquan Yang, Taihua Yang, Wenjing Li, Yingnan Liu, Yaru Shi, Aihua Wang, Peng Chen, Chao Liu, Qingyong Yang, Wenlin Yu, Chunyu Zhang   +12 more
wiley   +1 more source