Results 31 to 40 of about 17,749 (253)
Integrative bioinformatics approach identifies novel drug targets for hyperaldosteronism, with a focus on SHMT1 as a promising therapeutic candidate. [PDF]
Jia M +5 more
europepmc +3 more sources
Aldosterone is produced in the adrenal cortex and governs volume and electrolyte homeostasis. Hyperaldosteronism can occur either as primary aldosteronism (renin-independent) or secondary aldosteronism (renin-dependent). As the commonest cause of secondary hypertension, primary aldosteronism is associated with increased cardiovascular risk.
Troy H Puar, Meifen Zhang
openaire +3 more sources
Chirurgie der Hyperthyreose [PDF]
Pathophysiologie, Diagnostik, Operationsindikation und Vorbehandlung, chirurgisches Krankengut, Operationsverfahren und Nachbehandlung mit funktionellen Spätergebnissen wurden gezeigt.
Günther, B. +5 more
core +1 more source
Purpose The aim of this study was to examine the utility of fluoroscopic bony landmarks in predicting the location of the left adrenal vein during adrenal vein sampling (AVS).
Lucas R. Cusumano +5 more
doaj +1 more source
Vascular dysfunction and fibrosis in stroke-prone spontaneously hypertensive rats: the aldosterone-mineralocorticoid receptor-Nox1 Axis [PDF]
Aims: We questioned whether aldosterone and oxidative stress play a role in vascular damage in severe hypertension and investigated the role of Nox1 in this process.
Ceravolo, Graziela +7 more
core +1 more source
Downregulated serum 14, 15-epoxyeicosatrienoic acid is associated with abdominal aortic calcification in patients with primary aldosteronism [PDF]
Patients with primary aldosteronism (PA) have increased risk of target-organ damage, among which vascular calcification is an important indicator of cardiovascular mortality.
Gao, Jingwei +8 more
core +1 more source
Primary aldosteronism is most often caused by aldosterone-producing adenoma (APA) and bi-lateral adrenal hyperplasia. Most APAs are caused by somatic mutations of various ion channels and pumps, the most common being the inward-rectifying potassium ...
Nae Takizawa +12 more
doaj +1 more source
openAccessArticle: False ; cover date: 2015-01-01 ; pii: B978-0-12-801238-3.05067-4 ; Harvest Date: 2016-01-06 13:08:10 ; issueName: ; Page Range: - ; href scidir: http://www.sciencedirect.com/science/article/pii/B9780128012383050674 ; pubType:
Gail, Galasko, Galasko, Gail
openaire +2 more sources
Bioactive Candy: Effects of Licorice on the Cardiovascular System
Licorice, today chiefly utilized as a flavoring additive in tea, tobacco and candy, is one of the oldest used herbs for medicinal purposes and consists of up to 300 active compounds.
Mikkel R. Deutch +4 more
doaj +1 more source
Paradigm shift on the role of mineralocorticoid receptor antagonists in hypertension therapy
The literature review is devoted to modern ideas about the role of hyperaldosteronism as one of the important pathophysiological links in hypertension (HTN) development.
S. R. Gilyarevsky, D. O. Ladygina
doaj +1 more source

