Results 121 to 130 of about 100,236 (366)
Mispositioned Neurokinin-1 Receptor-Expressing Neurons Underlie Heat Hyperalgesia in Disabled-1 Mutant Mice. [PDF]
, 2019 Reelin (Reln) and Disabled-1 (Dab1) participate in the Reln-signaling pathway and when either is deleted, mutant mice have the same spinally mediated behavioral abnormalities, increased sensitivity to noxious heat and a profound loss in mechanical ...
Basbaum, Allan I +5 more
core
Fear of pain potentiates nocebo hyperalgesia
Journal of Pain Research, 2015 Nocebo hyperalgesia has received sparse experimental attention compared to placebo analgesia. The aim of the present study was to investigate if personality traits and fear of pain could predict experimental nocebo hyperalgesia.
P. Aslaksen, P. S. Lyby
semanticscholar +1 more source
Veterinary Record Case Reports, EarlyView.Abstract A 9‐month‐old Simmental fattening bull with a history of anorexia, severe salivation and marked bilateral swelling of the mandible was referred to the clinic. The physical examination and radiographs revealed a bilateral complete displaced mandibular fracture involving the symphysis. Treatment consisted of rostral mandibulectomy, including the
Cassandra Eibl +4 more
wiley +1 more source
Analgesic Effects of Fatty Acid Amide Hydrolase Inhibition in a Rat Model of Neuropathic Pain [PDF]
, 2006 Cannabinoid-based medicines have therapeutic potential for the treatment of pain. Augmentation of levels of endocannabinoids with inhibitors of fatty acid amide hydrolase (FAAH) is analgesic in models of acute and inflammatory pain states.
Barrett, David +4 more
core +2 more sources
mTOR, a new potential target for chronic pain and opioid-induced tolerance and hyperalgesia
Molecular Pain, 2015 Chronic pain is a major public health problem with limited treatment options. Opioids remain a routine treatment for chronic pain, but extended exposure to opioid therapy can produce opioid tolerance and hyperalgesia.
B. Lutz +4 more
semanticscholar +1 more source
Alcohol, Clinical and Experimental Research, EarlyView.This study shows that chronic alcohol exposure leads to sex‐specific disruptions in local field potentials, specifically causing changes to amygdala oscillations in females and prefrontal cortical and nucleus accumbens oscillations in males. These data may explain some of the sex differences observed in alcohol misuse and provide potential biomarkers ...
Kelly A. Hewitt +4 more
wiley +1 more source
Loss of neurons from laminas I-III of the spinal dorsal horn is not required for development of tactile allodynia in the spared nerve injury model of neuropathic pain [PDF]
, 2005 It has been proposed that death of inhibitory interneurons in the dorsal horn contributes to the neuropathic pain that follows partial nerve injury. In this study, we have used two approaches to test whether there is neuronal death in the dorsal horn in ...
Arham, A.Z. +3 more
core +2 more sources
Australian Dental Journal, EarlyView.Abstract Background Cracks in teeth are the third most common reason for tooth loss. The primary aim of this study was to identify the patient‐specific and tooth‐specific characteristics of individuals who presented to a private general dental practice with cracked posterior teeth.
P Renner, U Krishnan, A Moule, M Swain
wiley +1 more source
Biomolecules & Biomedicine, 2007 The experience of pain is variable among certain cultures, ethnical groups and among individuals. This variability can be explained by environmental influence, genetic predisposition and plasticity of the existing neuronal pathways.
Katarina Vukojević +2 more
doaj +1 more source
Quantitative sensory testing in painful hand osteoarthritis demonstrates features of peripheral sensitisation. [PDF]
, 2012 Hand osteoarthritis (HOA) is a prevalent condition for which treatments are based on analgesia and physical therapies. Our primary objective was to evaluate pain perception in participants with HOA by assessing the characteristics of nodal involvement ...
Ejindu, V +5 more
core +2 more sources